Small-Molecule Modulation of PPARs for the Treatment of Prevalent Vascular Retinal Diseases
Dou, Xiaozheng, Duerfeldt, Adam S
Published in International journal of molecular sciences (04.12.2020)
Published in International journal of molecular sciences (04.12.2020)
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Journal Article
Cycloadditions of Noncomplementary Substituted 1,2,3-Triazines
Anderson, Erin D, Duerfeldt, Adam S, Zhu, Kaicheng, Glinkerman, Christopher M, Boger, Dale L
Published in Organic letters (03.10.2014)
Published in Organic letters (03.10.2014)
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Journal Article
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding
Que, Nanette L. S, Crowley, Vincent M, Duerfeldt, Adam S, Zhao, Jinbo, Kent, Caitlin N, Blagg, Brian S. J, Gewirth, Daniel T
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Property space mapping of Pseudomonas aeruginosa permeability to small molecules
Leus, Inga V, Weeks, Jon W, Bonifay, Vincent, Shen, Yue, Yang, Liang, Cooper, Connor J, Nath, Dinesh, Duerfeldt, Adam S, Smith, Jeremy C, Parks, Jerry M, Rybenkov, Valentin V, Zgurskaya, Helen I
Published in Scientific reports (17.05.2022)
Published in Scientific reports (17.05.2022)
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Journal Article
Author Correction: Property space mapping of Pseudomonas aeruginosa permeability to small molecules
Leus, Inga V, Weeks, Jon W, Bonifay, Vincent, Shen, Yue, Yang, Liang, Cooper, Connor J, Nath, Dinesh, Duerfeldt, Adam S, Smith, Jeremy C, Parks, Jerry M, Rybenkov, Valentin V, Zgurskaya, Helen I
Published in Scientific reports (01.06.2023)
Published in Scientific reports (01.06.2023)
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Journal Article
CpxA Phosphatase Inhibitor Activates CpxRA and Is a Potential Treatment for Uropathogenic Escherichia coli in a Murine Model of Infection
Fortney, Kate R, Smith, Sara N, van Rensburg, Julia J, Brothwell, Julie A, Gardner, Jessi J, Katz, Barry P, Ahsan, Nagib, Duerfeldt, Adam S, Mobley, Harry L T, Spinola, Stanley M
Published in Microbiology spectrum (27.04.2022)
Published in Microbiology spectrum (27.04.2022)
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Journal Article
A Fundamental Relationship between Hydrophobic Properties and Biological Activity for the Duocarmycin Class of DNA-Alkylating Antitumor Drugs: Hydrophobic-Binding-Driven Bonding
Wolfe, Amanda L, Duncan, Katharine K, Lajiness, James P, Zhu, Kaicheng, Duerfeldt, Adam S, Boger, Dale L
Published in Journal of medicinal chemistry (12.09.2013)
Published in Journal of medicinal chemistry (12.09.2013)
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Journal Article
Structure–Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens
Hu, Ziwei, Leus, Inga V., Chandar, Brinda, Sherborne, Bradley S., Avila, Quentin P., Rybenkov, Valentin V., Zgurskaya, Helen I., Duerfeldt, Adam S.
Published in Journal of medicinal chemistry (27.10.2022)
Published in Journal of medicinal chemistry (27.10.2022)
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Journal Article
Design and Assessment of First-Generation Heterobifunctional PPARα/STING Modulators
Hu, Bo, Cui, Yi, Lee, Julia J., Ma, Jian-Xing, Duerfeldt, Adam S.
Published in ACS medicinal chemistry letters (08.08.2024)
Published in ACS medicinal chemistry letters (08.08.2024)
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Journal Article
Correction to “Structure–Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens”
Hu, Ziwei, Leus, Inga V., Chandar, Brinda, Sherborne, Bradley S., Avila, Quentin P., Rybenkov, Valentin V., Zgurskaya, Helen I., Duerfeldt, Adam S.
Published in Journal of medicinal chemistry (12.10.2023)
Published in Journal of medicinal chemistry (12.10.2023)
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Journal Article
Evolution of a 4‑Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders
Dou, Xiaozheng, Nath, Dinesh, Shin, Henry, Nurmemmedov, Elmar, Bourne, Philip C, Ma, Jian-Xing, Duerfeldt, Adam S
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Journal Article
Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation
Di, Xiao-Jing, Wang, Ya-Juan, Han, Dong-Yun, Fu, Yan-Lin, Duerfeldt, Adam S., Blagg, Brian S.J., Mu, Ting-Wei
Published in The Journal of biological chemistry (29.04.2016)
Published in The Journal of biological chemistry (29.04.2016)
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Journal Article
Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold
Crowley, Vincent M, Khandelwal, Anuj, Mishra, Sanket, Stothert, Andrew R, Huard, Dustin J. E, Zhao, Jinbo, Muth, Aaron, Duerfeldt, Adam S, Kizziah, James L, Lieberman, Raquel L, Dickey, Chad A, Blagg, Brian S. J
Published in Journal of medicinal chemistry (14.04.2016)
Published in Journal of medicinal chemistry (14.04.2016)
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Journal Article
Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARα selective agonists: New leads for oculovascular conditions
Dou, Xiao-Zheng, Nath, Dinesh, Shin, Younghwa, Ma, Jian-Xing, Duerfeldt, Adam S.
Published in Bioorganic & medicinal chemistry letters (01.09.2018)
Published in Bioorganic & medicinal chemistry letters (01.09.2018)
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Journal Article
Design, Synthesis, and Structure–Activity Relationships of Biaryl Anilines as Subtype-Selective PPAR-alpha Agonists
Lee, Julia J., Hu, Ziwei, Wang, Yuhong Anna, Nath, Dinesh, Liang, Wentao, Cui, Yi, Ma, Jian-Xing, Duerfeldt, Adam S.
Published in ACS medicinal chemistry letters (08.06.2023)
Published in ACS medicinal chemistry letters (08.06.2023)
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Journal Article