Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor
Hudson, Brian D., Due-Hansen, Maria E., Christiansen, Elisabeth, Hansen, Anna Mette, Mackenzie, Amanda E., Murdoch, Hannah, Pandey, Sunil K., Ward, Richard J., Marquez, Rudi, Tikhonova, Irina G., Ulven, Trond, Milligan, Graeme
Published in The Journal of biological chemistry (14.06.2013)
Published in The Journal of biological chemistry (14.06.2013)
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Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans
WAGNER, Robert, KAISER, Gabriele, FRITSCHE, Andreas, HÄRING, Hans-Ulrich, ULLRICH, Susanne, GERST, Felicia, CHRISTIANSEN, Elisabeth, DUE-HANSEN, Maria E, GRUNDMANN, Manuel, MACHICAO, Fausto, PETER, Andreas, KOSTENIS, Evi, ULVEN, Trond
Published in Diabetes (New York, N.Y.) (01.06.2013)
Published in Diabetes (New York, N.Y.) (01.06.2013)
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A protocol for amide bond formation with electron deficient amines and sterically hindered substrates
Due-Hansen, Maria E., Pandey, Sunil K., Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F., Ulven, Trond
Published in Organic & biomolecular chemistry (14.01.2016)
Published in Organic & biomolecular chemistry (14.01.2016)
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Identification of a Potent and Selective Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist with Favorable Physicochemical and in Vitro ADME Properties
Christiansen, Elisabeth, Urban, Christian, Grundmann, Manuel, Due-Hansen, Maria E, Hagesaether, Ellen, Schmidt, Johannes, Pardo, Leonardo, Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias, Ulven, Trond
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Journal Article
Discovery of a Potent and Selective Free Fatty Acid Receptor 1 Agonist with Low Lipophilicity and High Oral Bioavailability
Christiansen, Elisabeth, Due-Hansen, Maria E, Urban, Christian, Grundmann, Manuel, Schmidt, Johannes, Hansen, Steffen V. F, Hudson, Brian D, Zaibi, Mohamed, Markussen, Stine B, Hagesaether, Ellen, Milligan, Graeme, Cawthorne, Michael A, Kostenis, Evi, Kassack, Matthias U, Ulven, Trond
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40
Schmidt, Johannes, Liebscher, Kathrin, Merten, Nicole, Grundmann, Manuel, Mielenz, Manfred, Sauerwein, Helga, Christiansen, Elisabeth, Due-Hansen, Maria E., Ulven, Trond, Ullrich, Susanne, Gomeza, Jesús, Drewke, Christel, Kostenis, Evi
Published in The Journal of biological chemistry (08.04.2011)
Published in The Journal of biological chemistry (08.04.2011)
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Journal Article
Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists: Mesylpropoxy Appendage Lowers Lipophilicity and Improves ADME Properties
Christiansen, Elisabeth, Due-Hansen, Maria E, Urban, Christian, Grundmann, Manuel, Schröder, Ralf, Hudson, Brian D, Milligan, Graeme, Cawthorne, Michael A, Kostenis, Evi, Kassack, Matthias U, Ulven, Trond
Published in Journal of medicinal chemistry (26.07.2012)
Published in Journal of medicinal chemistry (26.07.2012)
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Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy
Hansen, Steffen V. F, Christiansen, Elisabeth, Urban, Christian, Hudson, Brian D, Stocker, Claire J, Due-Hansen, Maria E, Wargent, Ed T, Shimpukade, Bharat, Almeida, Reinaldo, Ejsing, Christer S, Cawthorne, Michael A, Kassack, Matthias U, Milligan, Graeme, Ulven, Trond
Published in Journal of medicinal chemistry (24.03.2016)
Published in Journal of medicinal chemistry (24.03.2016)
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Journal Article
Structure−Activity Study of Dihydrocinnamic Acids and Discovery of the Potent FFA1 (GPR40) Agonist TUG-469
Christiansen, Elisabeth, Due-Hansen, Maria E, Urban, Christian, Merten, Nicole, Pfleiderer, Michael, Karlsen, Kasper K, Rasmussen, Sanne S, Steensgaard, Mette, Hamacher, Alexandra, Schmidt, Johannes, Drewke, Christel, Petersen, Rasmus Koefoed, Kristiansen, Karsten, Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias U, Ulven, Trond
Published in ACS medicinal chemistry letters (14.10.2010)
Published in ACS medicinal chemistry letters (14.10.2010)
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A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial
Isetta, Valentina, Negrín, Miguel A, Monasterio, Carmen, Masa, Juan F, Feu, Nuria, Álvarez, Ainhoa, Campos-Rodriguez, Francisco, Ruiz, Concepción, Abad, Jorge, Vázquez-Polo, Francisco J, Farré, Ramon, Galdeano, Marina, Lloberes, Patricia, Embid, Cristina, de la Peña, Mónica, Puertas, Javier, Dalmases, Mireia, Salord, Neus, Corral, Jaime, Jurado, Bernabé, León, Carmen, Egea, Carlos, Muñoz, Aida, Parra, Olga, Cambrodi, Roser, Martel-Escobar, María, Arqué, Meritxell, Montserrat, Josep M
Published in Thorax (01.11.2015)
Published in Thorax (01.11.2015)
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Prone positioning as a bridge to recovery from refractory hypoxaemia following lung transplantation
Riera, Jordi, Maldonado, Carolina, Mazo, Cristopher, Martínez, María, Baldirà, Jaume, Lagunes, Leonel, Augustin, Salvador, Roman, Antonio, Due, Maria, Rello, Jordi, Levine, Deborah J.
Published in Interactive cardiovascular and thoracic surgery (01.08.2017)
Published in Interactive cardiovascular and thoracic surgery (01.08.2017)
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PENGARUH GAYA BELAJAR DAN SIKAP DISIPLIN TERHADAP HASIL BELAJAR MATEMATIKA SISWA SMP
Due, Maria Dorotea, Ningsih, Ningsih, Seto, Stefania Baptis
Published in JUPIKA: JURNAL PENDIDIKAN MATEMATIKA (18.09.2023)
Published in JUPIKA: JURNAL PENDIDIKAN MATEMATIKA (18.09.2023)
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The Role of Liquid Organic Fertiliser on the Growth of Rice Paddy Crops in Pape Village, Bajawa District, Ngada Regency, East Nusa Tenggara Province
Lea, Victoria Coo, Prihatin, Prihatin, Hamakonda, Umbu Awang, Puspita, Victoria Ayu, Taus, Igniosa, Due, Maria Serviana
Published in Jurnal Biologi Tropis (27.06.2024)
Published in Jurnal Biologi Tropis (27.06.2024)
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Small-scale fire performance assessment of intumescent coatings on metal tubes containing ammonium nitrate. A stepping-stone towards their application as a fire safety measure on road transportation tanks?
Due-Hansen, Maria E., Johannessen, Tom Cato, Bolsønes, Marianne
Published in Journal of loss prevention in the process industries (01.11.2021)
Published in Journal of loss prevention in the process industries (01.11.2021)
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Mucus can change the permeation rank order of drug candidates
Hagesaether, Ellen, Christiansen, Elisabeth, Due-Hansen, Maria Elisabeth, Ulven, Trond
Published in International journal of pharmaceutics (16.08.2013)
Published in International journal of pharmaceutics (16.08.2013)
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ChemInform Abstract: A Protocol for Amide Bond Formation with Electron Deficient Amines and Sterically Hindered Substrates
Due‐Hansen, Maria E., Pandey, Sunil K., Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F., Ulven, Trond
Published in ChemInform (01.04.2016)
Published in ChemInform (01.04.2016)
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