Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins
Ali, Youssif M, Ferrari, Matteo, Lynch, Nicholas J, Yaseen, Sadam, Dudler, Thomas, Gragerov, Sasha, Demopulos, Gregory, Heeney, Jonathan L, Schwaeble, Wilhelm J
Published in Frontiers in immunology (05.07.2021)
Published in Frontiers in immunology (05.07.2021)
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Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury
Mercurio, Domenico, Pischiutta, Francesca, Seminara, Serena, Tribuzio, Francesca, Lisi, Ilaria, Pasetto, Laura, Bonetto, Valentina, De Simoni, Maria-Grazia, Schwaeble, Wilhelm, Yaseen, Sadam, Dudler, Thomas, Zanier, Elisa R, Fumagalli, Stefano
Published in Journal of neuroinflammation (28.05.2024)
Published in Journal of neuroinflammation (28.05.2024)
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Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury
Schwaeble, Wilhelm J, Lynch, Nicholas J, Clark, James E, Marber, Michael, Samani, Nilesh J, Ali, Youssif Mohammed, Dudler, Thomas, Parent, Brian, Lhotta, Karl, Wallis, Russell, Farrar, Conrad A, Sacks, Steven, Lee, Haekyung, Zhang, Ming, Iwaki, Daisuke, Takahashi, Minoru, Fujita, Teizo, Tedford, Clark E, Stover, Cordula M
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2011)
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Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2
Yaseen, Sadam, Demopulos, Gregory, Dudler, Thomas, Yabuki, Munehisa, Wood, Christi L, Cummings, W Jason, Tjoelker, Larry W, Fujita, Teizo, Sacks, Steven, Garred, Peter, Andrew, Peter, Sim, Robert B, Lachmann, Peter J, Wallis, Russell, Lynch, Nicholas, Schwaeble, Wilhelm J
Published in The FASEB journal (01.05.2017)
Published in The FASEB journal (01.05.2017)
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Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1
Orsini, Franca, Chrysanthou, Elvina, Dudler, Thomas, Cummings, W Jason, Takahashi, Minoru, Fujita, Teizo, Demopulos, Gregory, De Simoni, Maria-Grazia, Schwaeble, Wilhelm
Published in Journal of neuroinflammation (30.08.2016)
Published in Journal of neuroinflammation (30.08.2016)
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The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection
Ali, Youssif M, Lynch, Nicholas J, Haleem, Kashif S, Fujita, Teizo, Endo, Yuichi, Hansen, Soren, Holmskov, Uffe, Takahashi, Kazue, Stahl, Gregory L, Dudler, Thomas, Girija, Umakhanth V, Wallis, Russell, Kadioglu, Aras, Stover, Cordula M, Andrew, Peter W, Schwaeble, Wilhelm J
Published in PLoS pathogens (01.07.2012)
Published in PLoS pathogens (01.07.2012)
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Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy
Gavriilaki, Eleni, Ho, Vincent T, Schwaeble, Wilhelm, Dudler, Thomas, Daha, Mohamed, Fujita, Teizo, Jodele, Sonata
Published in Experimental hematology & oncology (19.12.2021)
Published in Experimental hematology & oncology (19.12.2021)
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Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice
Ali, Youssif M, Lynch, Nicholas J, Shaaban, Ahmed A, Rizk, Dina E, Abdel-Rahman, Shaymaa H, Khatri, Priyanka, Yabuki, Munehisa, Yaseen, Sadam, Dudler, Thomas, Demopulos, Gregory, Schwaeble, Wilhelm J
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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Identification of the Phosphorylation Sites of Cytosolic Phospholipase A2 in Agonist-stimulated Human Platelets and HeLa Cells
Börsch-Haubold, A G, Bartoli, F, Asselin, J, Dudler, T, Kramer, R M, Apitz-Castro, R, Watson, S P, Gelb, M H
Published in The Journal of biological chemistry (20.02.1998)
Published in The Journal of biological chemistry (20.02.1998)
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Development of Pharmacodynamic Assays to Assess Ex Vivo Masp-2 Inhibition and Their Use to Characterize the Pharmacodynamics of Narsoplimab (OMS721) in Humans and Monkeys
Freeman, Jeremy, Cummings, Jason, Chuidian, Marither, Dudler, Thomas
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease
Belcher, John D., Nguyen, Julia, Chen, Chunsheng, Abdulla, Fuad, Conglin, Ruan, Ivy, Zalaya K., Cummings, Jason, Dudler, Thomas, Vercellotti, Gregory M.
Published in Translational research : the journal of laboratory and clinical medicine (01.11.2022)
Published in Translational research : the journal of laboratory and clinical medicine (01.11.2022)
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METHODS FOR INHIBITING ANGIOGENESIS IN A SUBJECT IN NEED THEREOF
DUDLER THOMAS, TJOELKER LARRY, DEMOPULOS GREGORY A, SCHWAEBLE HANS WILHELM
Year of Publication 09.02.2023
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Year of Publication 09.02.2023
Patent
MASP-2의 세린 프로테아제 도메인에 결합하는 치료 항체 및 이것의 용도
NOLLERT VON SPECHT PETER KURT, DUDLER THOMAS, YABUKI MUNEHISA, YASEEN SADAM
Year of Publication 29.07.2024
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Year of Publication 29.07.2024
Patent