DICER1: mutations, microRNAs and mechanisms
Foulkes, William D., Priest, John R., Duchaine, Thomas F.
Published in Nature reviews. Cancer (01.10.2014)
Published in Nature reviews. Cancer (01.10.2014)
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Distinct, opposing functions for CFIm59 and CFIm68 in mRNA alternative polyadenylation of Pten and in the PI3K/Akt signalling cascade
Tseng, Hsin-Wei, Mota-Sydor, Anthony, Leventis, Rania, Jovanovic, Predrag, Topisirovic, Ivan, Duchaine, Thomas F
Published in Nucleic acids research (09.09.2022)
Published in Nucleic acids research (09.09.2022)
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Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1
Rouya, Christopher, Siddiqui, Nadeem, Morita, Masahiro, Duchaine, Thomas F, Fabian, Marc R, Sonenberg, Nahum
Published in RNA (Cambridge) (01.09.2014)
Published in RNA (Cambridge) (01.09.2014)
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microRNA-mediated translation repression through GYF-1 and IFE-4 in C. elegans development
Mayya, Vinay K, Flamand, Mathieu N, Lambert, Alice M, Jafarnejad, Seyed Mehdi, Wohlschlegel, James A, Sonenberg, Nahum, Duchaine, Thomas F
Published in Nucleic acids research (21.05.2021)
Published in Nucleic acids research (21.05.2021)
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Cap-binding protein 4EHP effects translation silencing by microRNAs
Chapat, Clément, Jafarnejad, Seyed Mehdi, Matta-Camacho, Edna, Hesketh, Geoffrey G., Gelbart, Idit A., Attig, Jan, Gkogkas, Christos G., Alain, Tommy, Stern-Ginossar, Noam, Fabian, Marc R., Gingras, Anne-Claude, Duchaine, Thomas F., Sonenberg, Nahum
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2017)
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A non-canonical site reveals the cooperative mechanisms of microRNA-mediated silencing
Flamand, Mathieu N, Gan, Hin Hark, Mayya, Vinay K, Gunsalus, Kristin C, Duchaine, Thomas F
Published in Nucleic acids research (07.07.2017)
Published in Nucleic acids research (07.07.2017)
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MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F
Mathonnet, Géraldine, Fabian, Marc R, Svitkin, Yuri V, Parsyan, Armen, Huck, Laurent, Murata, Takayuki, Biffo, Stefano, Merrick, William C, Darzynkiewicz, Edward, Pillai, Ramesh S, Filipowicz, Witold, Duchaine, Thomas F, Sonenberg, Nahum
Published in Science (American Association for the Advancement of Science) (21.09.2007)
Published in Science (American Association for the Advancement of Science) (21.09.2007)
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Paraspeckle-independent co-transcriptional regulation of nuclear microRNA biogenesis by SFPQ
Thivierge, Caroline, Bellefeuille, Maxime, Diwan, Sarah-Slim, Dyakov, Boris J.A., Leventis, Rania, Perron, Gabrielle, Najafabadi, Hamed S., Gravel, Simon-Pierre, Gingras, Anne-Claude, Duchaine, Thomas F.
Published in Cell reports (Cambridge) (24.09.2024)
Published in Cell reports (Cambridge) (24.09.2024)
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Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation
Fabian, Marc R., Mathonnet, Géraldine, Sundermeier, Thomas, Mathys, Hansruedi, Zipprich, Jakob T., Svitkin, Yuri V., Rivas, Fabiola, Jinek, Martin, Wohlschlegel, James, Doudna, Jennifer A., Chen, Chyi-Ying A., Shyu, Ann-Bin, Yates, John R., Hannon, Gregory J., Filipowicz, Witold, Duchaine, Thomas F., Sonenberg, Nahum
Published in Molecular cell (24.09.2009)
Published in Molecular cell (24.09.2009)
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The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism
Izreig, Said, Samborska, Bozena, Johnson, Radia M., Sergushichev, Alexey, Ma, Eric H., Lussier, Carine, Loginicheva, Ekaterina, Donayo, Ariel O., Poffenberger, Maya C., Sagan, Selena M., Vincent, Emma E., Artyomov, Maxim N., Duchaine, Thomas F., Jones, Russell G.
Published in Cell reports (Cambridge) (16.08.2016)
Published in Cell reports (Cambridge) (16.08.2016)
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Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway
Vasale, Jessica J, Gu, Weifeng, Thivierge, Caroline, Batista, Pedro J, Claycomb, Julie M, Youngman, Elaine M, Duchaine, Thomas F, Mello, Craig C, Conte, Darryl Jr
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2010)
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Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules
Cipriani, Patricia Giselle, Bay, Olivia, Zinno, John, Gutwein, Michelle, Gan, Hin Hark, Mayya, Vinay K, Chung, George, Chen, Jia-Xuan, Fahs, Hala, Guan, Yu, Duchaine, Thomas F, Selbach, Matthias, Piano, Fabio, Gunsalus, Kristin C
Published in eLife (05.07.2021)
Published in eLife (05.07.2021)
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Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
Duchaine, Thomas F., Wohlschlegel, James A., Kennedy, Scott, Bei, Yanxia, Conte, Darryl, Pang, KaMing, Brownell, Daniel R., Harding, Sandra, Mitani, Shohei, Ruvkun, Gary, Yates, John R., Mello, Craig C.
Published in Cell (27.01.2006)
Published in Cell (27.01.2006)
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Translational control of ERK signaling through miRNA/4EHP-directed silencing
Jafarnejad, Seyed Mehdi, Chapat, Clément, Matta-Camacho, Edna, Gelbart, Idit Anna, Hesketh, Geoffrey G, Arguello, Meztli, Garzia, Aitor, Kim, Sung-Hoon, Attig, Jan, Shapiro, Maayan, Morita, Masahiro, Khoutorsky, Arkady, Alain, Tommy, Gkogkas, Christos G, Stern-Ginossar, Noam, Tuschl, Thomas, Gingras, Anne-Claude, Duchaine, Thomas F, Sonenberg, Nahum
Published in eLife (07.02.2018)
Published in eLife (07.02.2018)
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Journal Article
Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi
Thivierge, Caroline, Makil, Neetha, Flamand, Mathieu, Vasale, Jessica J, Mello, Craig C, Wohlschlegel, James, Conte, Darryl, Duchaine, Thomas F
Published in Nature structural & molecular biology (01.01.2012)
Published in Nature structural & molecular biology (01.01.2012)
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Journal Article
Mechanistic Insights into MicroRNA-Mediated Gene Silencing
Duchaine, Thomas F, Fabian, Marc R
Published in Cold Spring Harbor perspectives in biology (01.03.2019)
Published in Cold Spring Harbor perspectives in biology (01.03.2019)
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