Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders
Yang, Chengran, Farias, Fabiana H. G., Ibanez, Laura, Suhy, Adam, Sadler, Brooke, Fernandez, Maria Victoria, Wang, Fengxian, Bradley, Joseph L., Eiffert, Brett, Bahena, Jorge A., Budde, John P., Li, Zeran, Dube, Umber, Sung, Yun Ju, Mihindukulasuriya, Kathie A., Morris, John C., Fagan, Anne M., Perrin, Richard J., Benitez, Bruno A., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos
Published in Nature neuroscience (01.09.2021)
Published in Nature neuroscience (01.09.2021)
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Journal Article
A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
Del-Aguila, Jorge L, Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A, Budde, John P, Fernandez, Maria Victoria, Ibanez, Laura, Bradley, Joseph, Wang, Fengxian, Bergmann, Kristy, Davenport, Richard, Morris, John C, Holtzman, David M, Perrin, Richard J, Benitez, Bruno A, Dougherty, Joseph, Cruchaga, Carlos, Harari, Oscar
Published in Alzheimer's research & therapy (09.08.2019)
Published in Alzheimer's research & therapy (09.08.2019)
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Journal Article
TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers
Del-Aguila, Jorge L, Benitez, Bruno A, Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A, Budde, John P, Farias, Fabiana H G, Fernández, Maria Victoria, Ibanez, Laura, Jiang, Shan, Perrin, Richard J, Cairns, Nigel J, Morris, John C, Harari, Oscar, Cruchaga, Carlos
Published in Molecular neurodegeneration (08.05.2019)
Published in Molecular neurodegeneration (08.05.2019)
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Journal Article
Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels
Ibanez, Laura, Dube, Umber, Saef, Benjamin, Budde, John, Black, Kathleen, Medvedeva, Alexandra, Del-Aguila, Jorge L, Davis, Albert A, Perlmutter, Joel S, Harari, Oscar, Benitez, Bruno A, Cruchaga, Carlos
Published in BMC neurology (15.11.2017)
Published in BMC neurology (15.11.2017)
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Journal Article
Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease
Fernández, Maria Victoria, Kim, Jong Hun, Budde, John P, Black, Kathleen, Medvedeva, Alexandra, Saef, Ben, Deming, Yuetiva, Del-Aguila, Jorge, Ibañez, Laura, Dube, Umber, Harari, Oscar, Norton, Joanne, Chasse, Rachel, Morris, John C, Goate, Alison, Cruchaga, Carlos
Published in PLoS genetics (01.11.2017)
Published in PLoS genetics (01.11.2017)
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Journal Article
Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure
Li, Zeran, Del-Aguila, Jorge L, Dube, Umber, Budde, John, Martinez, Rita, Black, Kathleen, Xiao, Qingli, Cairns, Nigel J, Dougherty, Joseph D, Lee, Jin-Moo, Morris, John C, Bateman, Randall J, Karch, Celeste M, Cruchaga, Carlos, Harari, Oscar
Published in Genome medicine (08.06.2018)
Published in Genome medicine (08.06.2018)
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Journal Article
Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease
Ibanez, Laura, Dube, Umber, Davis, Albert A, Fernandez, Maria V, Budde, John, Cooper, Breanna, Diez-Fairen, Monica, Ortega-Cubero, Sara, Pastor, Pau, Perlmutter, Joel S, Cruchaga, Carlos, Benitez, Bruno A
Published in Frontiers in neuroscience (10.04.2018)
Published in Frontiers in neuroscience (10.04.2018)
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Journal Article
Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease
Ibanez, Laura, Bahena, Jorge A, Yang, Chengran, Dube, Umber, Farias, Fabiana H G, Budde, John P, Bergmann, Kristy, Brenner-Webster, Carol, Morris, John C, Perrin, Richard J, Cairns, Nigel J, O'Donnell, John, Álvarez, Ignacio, Diez-Fairen, Monica, Aguilar, Miquel, Miller, Rebecca, Davis, Albert A, Pastor, Pau, Kotzbauer, Paul, Campbell, Meghan C, Perlmutter, Joel S, Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos, Benitez, Bruno A
Published in Acta neuropathologica communications (19.11.2020)
Published in Acta neuropathologica communications (19.11.2020)
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Journal Article
SnapshotDx Quiz: May 2021
Raval, Neel P, Dube, Umber, Musiek, Amy
Published in Journal of investigative dermatology (01.05.2021)
Published in Journal of investigative dermatology (01.05.2021)
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Journal Article
SnapshotDx Quiz: September 2020
McEvoy, Aubriana, Dube, Umber, Musiek, Amy, Anadkat, Milan
Published in Journal of investigative dermatology (01.09.2020)
Published in Journal of investigative dermatology (01.09.2020)
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Journal Article
APOE genotype regulates pathology and disease progression in synucleinopathy
Davis, Albert A, Inman, Casey E, Wargel, Zachary M, Dube, Umber, Freeberg, Brittany M, Galluppi, Alexander, Haines, Jessica N, Dhavale, Dhruva D, Miller, Rebecca, Choudhury, Fahim A, Sullivan, Patrick M, Cruchaga, Carlos, Perlmutter, Joel S, Ulrich, Jason D, Benitez, Bruno A, Kotzbauer, Paul T, Holtzman, David M
Published in Science translational medicine (05.02.2020)
Published in Science translational medicine (05.02.2020)
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The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk
Deming, Yuetiva, Filipello, Fabia, Cignarella, Francesca, Cantoni, Claudia, Hsu, Simon, Mikesell, Robert, Li, Zeran, Del-Aguila, Jorge L, Dube, Umber, Farias, Fabiana Geraldo, Bradley, Joseph, Budde, John, Ibanez, Laura, Fernandez, Maria Victoria, Blennow, Kaj, Zetterberg, Henrik, Heslegrave, Amanda, Johansson, Per M, Svensson, Johan, Nellgård, Bengt, Lleo, Alberto, Alcolea, Daniel, Clarimon, Jordi, Rami, Lorena, Molinuevo, José Luis, Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Ewers, Michael, Harari, Oscar, Haass, Christian, Brett, Thomas J, Benitez, Bruno A, Karch, Celeste M, Piccio, Laura, Cruchaga, Carlos
Published in Science translational medicine (14.08.2019)
Published in Science translational medicine (14.08.2019)
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Journal Article
Use of medical care biases associations between Parkinson disease and other medical conditions
Gross, Anat, Racette, Brad A, Camacho-Soto, Alejandra, Dube, Umber, Searles Nielsen, Susan
Published in Neurology (12.06.2018)
Published in Neurology (12.06.2018)
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Journal Article
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion
Li, Zeran, Farias, Fabiana H. G., Dube, Umber, Del-Aguila, Jorge L., Mihindukulasuriya, Kathie A., Fernandez, Maria Victoria, Ibanez, Laura, Budde, John P., Wang, Fengxian, Lake, Allison M., Deming, Yuetiva, Perez, James, Yang, Chengran, Bahena, Jorge A., Qin, Wei, Bradley, Joseph L., Davenport, Richard, Bergmann, Kristy, Morris, John C., Perrin, Richard J., Benitez, Bruno A., Dougherty, Joseph D., Harari, Oscar, Cruchaga, Carlos
Published in Acta neuropathologica (01.01.2020)
Published in Acta neuropathologica (01.01.2020)
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Journal Article
A comprehensive analysis of dementia cerebrospinal fluid biomarkers using GWAs, polygenic risk scores and Mendelian randomization in Parkinson’s disease: Genetics/atypical and other dementias
Ibanez, Laura, Bahena, Jorge Alberto, Dube, Umber, Farias, Fabiana H.G., Yang, Chengran, Harari, Oscar, Cruchaga, Carlos, Benitez, Bruno A.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
A comprehensive analysis of dementia cerebrospinal fluid biomarkers using GWAs, polygenic risk scores and Mendelian randomization in Parkinson’s disease
Ibanez, Laura, Bahena, Jorge Alberto, Dube, Umber, Farias, Fabiana H.G., Yang, Chengran, Harari, Oscar, Cruchaga, Carlos, Benitez, Bruno A.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Alzheimer‐associated circular RNA circHOMER1 regulates synaptic gene expression and cognition
Dube, Umber, Harari, Oscar, Zimmerman, Amber, Hafez, Alexander, Brigman, Jonathan, Cruchaga, Carlos, Mellios, Nikolaos, Benitez, Bruno A.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Alzheimer‐associated circular RNA circHOMER1 regulates synaptic gene expression and cognition: Molecular and cell biology: Neurodegeneration versus neuroprotection
Dube, Umber, Harari, Oscar, Zimmerman, Amber, Hafez, Alexander, Brigman, Jonathan, Cruchaga, Carlos, Mellios, Nikolaos, Benitez, Bruno A.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP
Jiang, Shan, Wen, Natalie, Li, Zeran, Dube, Umber, Del Aguila, Jorge, Budde, John, Martinez, Rita, Hsu, Simon, Fernandez, Maria V., Cairns, Nigel J., Harari, Oscar, Cruchaga, Carlos, Karch, Celeste M.
Published in Translational psychiatry (13.12.2018)
Published in Translational psychiatry (13.12.2018)
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