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Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2
Qian, Hongwu, Wu, Xuelan, Du, Ximing, Yao, Xia, Zhao, Xin, Lee, Joyce, Yang, Hongyuan, Yan, Nieng
Published in Cell (09.07.2020)
Published in Cell (09.07.2020)
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Structural basis for catalysis and substrate specificity of human ACAT1
Qian, Hongwu, Zhao, Xin, Yan, Renhong, Yao, Xia, Gao, Shuai, Sun, Xue, Du, Ximing, Yang, Hongyuan, Wong, Catherine C. L., Yan, Nieng
Published in Nature (London) (01.05.2020)
Published in Nature (London) (01.05.2020)
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Lipid droplet biogenesis and functions in health and disease
Zadoorian, Armella, Du, Ximing, Yang, Hongyuan
Published in Nature reviews. Endocrinology (23.05.2023)
Published in Nature reviews. Endocrinology (23.05.2023)
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Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2
Dong, Jiangqing, Du, Ximing, Wang, Huan, Wang, Jue, Lu, Chang, Chen, Xiang, Zhu, Zhiwen, Luo, Zhipu, Yu, Li, Brown, Andrew J., Yang, Hongyuan, Wu, Jia-Wei
Published in Nature communications (19.02.2019)
Published in Nature communications (19.02.2019)
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ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2)
Wang, Huan, Ma, Qianli, Qi, Yanfei, Dong, Jiangqing, Du, Ximing, Rae, James, Wang, Jue, Wu, Wei-Feng, Brown, Andrew J., Parton, Robert G., Wu, Jia-Wei, Yang, Hongyuan
Published in Molecular cell (07.02.2019)
Published in Molecular cell (07.02.2019)
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Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts
Chu, Bei-Bei, Liao, Ya-Cheng, Qi, Wei, Xie, Chang, Du, Ximing, Wang, Jiang, Yang, Hongyuan, Miao, Hong-Hua, Li, Bo-Liang, Song, Bao-Liang
Published in Cell (09.04.2015)
Published in Cell (09.04.2015)
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The role of oxysterol-binding protein and its related proteins in cancer
Du, Ximing, Turner, Nigel, Yang, Hongyuan
Published in Seminars in cell & developmental biology (01.09.2018)
Published in Seminars in cell & developmental biology (01.09.2018)
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TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine
Li, Yang Emma, Wang, Yichang, Du, Ximing, Zhang, Tizhong, Mak, Hoi Yin, Hancock, Sarah E., McEwen, Holly, Pandzic, Elvis, Whan, Renee M., Aw, Yvette Celine, Lukmantara, Ivan E., Yuan, Yiqiong, Dong, Xiuju, Don, Anthony, Turner, Nigel, Qi, Shiqian, Yang, Hongyuan
Published in The Journal of cell biology (07.06.2021)
Published in The Journal of cell biology (07.06.2021)
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ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane
Ghai, Rajesh, Du, Ximing, Wang, Huan, Dong, Jiangqing, Ferguson, Charles, Brown, Andrew J., Parton, Robert G., Wu, Jia-Wei, Yang, Hongyuan
Published in Nature communications (02.10.2017)
Published in Nature communications (02.10.2017)
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ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P2) and regulate its level at the plasma membrane
Ghai, Rajesh, Du, Ximing, Wang, Huan, Dong, Jiangqing, Ferguson, Charles, Brown, Andrew J., Parton, Robert G., Wu, Jia-Wei, Yang, Hongyuan
Published in Nature communications (02.10.2017)
Published in Nature communications (02.10.2017)
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AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway
Mak, Hoi Yin, Ouyang, Qian, Tumanov, Sergey, Xu, Jiesi, Rong, Ping, Dong, Feitong, Lam, Sin Man, Wang, Xiaowei, Lukmantara, Ivan, Du, Ximing, Gao, Mingming, Brown, Andrew J., Gong, Xin, Shui, Guanghou, Stocker, Roland, Huang, Xun, Chen, Shuai, Yang, Hongyuan
Published in Nature communications (25.11.2021)
Published in Nature communications (25.11.2021)
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ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets
Du, Ximing, Zhou, Linkang, Aw, Yvette Celine, Mak, Hoi Yin, Xu, Yanqing, Rae, James, Wang, Wenmin, Zadoorian, Armella, Hancock, Sarah E., Osborne, Brenna, Chen, Xiang, Wu, Jia-Wei, Turner, Nigel, Parton, Robert G., Li, Peng, Yang, Hongyuan
Published in The Journal of cell biology (06.01.2020)
Published in The Journal of cell biology (06.01.2020)
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Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase
Coates, Hudson W, Capell-Hattam, Isabelle M, Olzomer, Ellen M, Du, Ximing, Farrell, Rhonda, Yang, Hongyuan, Byrne, Frances L, Brown, Andrew J
Published in eLife (19.01.2023)
Published in eLife (19.01.2023)
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Novel mechanisms of intracellular cholesterol transport: oxysterol-binding proteins and membrane contact sites
Du, Ximing, Brown, Andrew J, Yang, Hongyuan
Published in Current opinion in cell biology (01.08.2015)
Published in Current opinion in cell biology (01.08.2015)
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role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking
Du, Ximing, Kumar, Jaspal, Ferguson, Charles, Schulz, Timothy A, Ong, Yan Shan, Hong, Wanjin, Prinz, William A, Parton, Robert G, Brown, Andrew J, Yang, Hongyuan
Published in The Journal of cell biology (10.01.2011)
Published in The Journal of cell biology (10.01.2011)
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TMEM41B and VMP1 are phospholipid scramblases
Zhang, Tizhong, Li, Yang E., Yuan, Yiqiong, Du, Ximing, Wang, Yichang, Dong, Xiuju, Yang, Hongyuan, Qi, Shiqian
Published in Autophagy (03.08.2021)
Published in Autophagy (03.08.2021)
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Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast
Fei, Weihua, Shui, Guanghou, Gaeta, Bruno, Du, Ximing, Kuerschner, Lars, Li, Peng, Brown, Andrew J, Wenk, Markus R, Parton, Robert G, Yang, Hongyuan
Published in The Journal of cell biology (11.02.2008)
Published in The Journal of cell biology (11.02.2008)
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SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase
Pagac, Martin, Cooper, Daniel E., Qi, Yanfei, Lukmantara, Ivan E., Mak, Hoi Yin, Wu, Zengying, Tian, Yuan, Liu, Zhonghua, Lei, Mona, Du, Ximing, Ferguson, Charles, Kotevski, Damian, Sadowski, Pawel, Chen, Weiqin, Boroda, Salome, Harris, Thurl E., Liu, George, Parton, Robert G., Huang, Xun, Coleman, Rosalind A., Yang, Hongyuan
Published in Cell reports (Cambridge) (01.11.2016)
Published in Cell reports (Cambridge) (01.11.2016)
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CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development[S]
Qi, Yanfei, Kapterian, Tamar S., Du, Ximing, Ma, Qianli, Fei, Weihua, Zhang, Yuxi, Huang, Xun, Dawes, Ian W., Yang, Hongyuan
Published in Journal of lipid research (01.05.2016)
Published in Journal of lipid research (01.05.2016)
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