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Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
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CX-4945, a selective inhibitor of casein kinase-2 (CK2), exhibits anti-tumor activity in hematologic malignancies including enhanced activity in chronic lymphocytic leukemia when combined with fludarabine and inhibitors of the B-cell receptor pathway
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Recurrent cyclin D2 mutations in myeloid neoplasms
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Extreme mutational selectivity of axitinib limits its potential use as a targeted therapeutic for BCR-ABL1-positive leukemia
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Mutations of the BCR-ABL-kinase domain occur in a minority of patients with stable complete cytogenetic response to imatinib
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Functional RNAi screen targeting cytokine and growth factor receptors reveals oncorequisite role for interleukin-2 gamma receptor in JAK3-mutation-positive leukemia
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Published in Oncogene (04.06.2015)
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Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells
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Characterization of BCR-ABL deletion mutants from patients with chronic myeloid leukemia
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Detection of ABL kinase domain mutations with denaturing high-performance liquid chromatography
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Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome
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Published in The New England journal of medicine (05.04.2001)
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An activating KRAS mutation in imatinib-resistant chronic myeloid leukemia
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Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
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Published in The Journal of pharmacology and experimental therapeutics (01.10.2000)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.2000)
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