Conformational changes of small molecules binding to proteins
Nicklaus, Marc C., Wang, Shaomeng, Driscoll, John S., Milne, George W.A.
Published in Bioorganic & medicinal chemistry (01.04.1995)
Published in Bioorganic & medicinal chemistry (01.04.1995)
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Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV
Marquez, Victor E, Tseng, Christopher K. H, Mitsuya, Hiroaki, Aoki, Shizuko, Kelley, James A, Ford, Harry, Roth, Jeri S, Broder, Samuel, Johns, David G, Driscoll, John S
Published in Journal of medicinal chemistry (01.03.1990)
Published in Journal of medicinal chemistry (01.03.1990)
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A new synthetic approach to the clinically useful, anti-HIV-active nucleoside, 9-(2,3-dideoxy-2-fluoro- β-D- threo-pentofuranosyl)adenine (β-FddA). Introduction of a 2′-β-fluoro substituent via inversion of a readily obtainable 2′-α-fluoro isomer
Siddiqui, Maqbool A., Driscoll, John S., Marquez, Victor E.
Published in Tetrahedron letters (26.03.1998)
Published in Tetrahedron letters (26.03.1998)
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Journal Article
In vitro induction of human immunodeficiency virus type 1 variants resistant to 2'-beta-Fluoro-2',3'-dideoxyadenosine
TANAKA, M, SRINIVAS, R. V, UENO, T, KAVLICK, M. F, HUI, F. K, FRIDLAND, A, DRISCOLL, J. S, MITSUYA, H
Published in Antimicrobial Agents and Chemotherapy (01.06.1997)
Published in Antimicrobial Agents and Chemotherapy (01.06.1997)
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Journal Article
Potent activity of 2'-beta-fluoro-2',3'-dideoxyadenosine against human immunodeficiency virus type 1 infection in hu-PBL-SCID mice
RUXRUNGTHAM, K, BOONE, E, FORD, H. JR, DRISCOLL, J. S, DAVEY, R. T, LANE, H. C
Published in Antimicrobial Agents and Chemotherapy (01.10.1996)
Published in Antimicrobial Agents and Chemotherapy (01.10.1996)
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Journal Article
Enhancement by hydroxyurea of the anti-human immunodeficiency virus type 1 potency of 2′-β-fluoro-2′,3′-dideoxyadenosine in peripheral blood mononuclear cells
Gao, Wen-Yi, Mitsuya, Hiroaki, Driscoll, John S., Johns, David G.
Published in Biochemical pharmacology (17.07.1995)
Published in Biochemical pharmacology (17.07.1995)
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Journal Article
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs
Barchi, Jr, J J, Marquez, V E, Driscoll, J S, Ford, Jr, H, Mitsuya, H, Shirasaka, T, Aoki, S, Kelley, J A
Published in Journal of medicinal chemistry (01.05.1991)
Published in Journal of medicinal chemistry (01.05.1991)
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Journal Article
A diastereoselective synthesis of (S,S)-α-fluoro-2,2-dimethyl-1,3-dioxolane-4-propanoic acid methyl ester, a key intermediate for the preparation of anti-HIV effective fluorodideoxynucleosides
Siddiqui, Maqbool A., Marquez, Victor E., Driscoll, John S., Barchi, Joseph J.
Published in Tetrahedron letters (16.05.1994)
Published in Tetrahedron letters (16.05.1994)
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Journal Article
Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogs
Kim, Chong Ho, Marquez, Victor E, Broder, Samuel, Mitsuya, Hiroaki, Driscoll, John S
Published in Journal of medicinal chemistry (01.05.1987)
Published in Journal of medicinal chemistry (01.05.1987)
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Journal Article
Effect of anti-HIV 2′-β-fluoro-2′,3′-dideoxynucleoside analogs on the cellular content of mitochondrial DNA and on lactate production
Tsai, Ching-Hwa, Doong, Shin-Lian, Johns, David G., Driscoll, John S., Cheng, Yung-Chi
Published in Biochemical pharmacology (07.10.1994)
Published in Biochemical pharmacology (07.10.1994)
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Journal Article
ESCHERICHIA-COLI MEDIATED BIOSYNTHESIS AND INVITRO ANTI-HIV ACTIVITY OF LIPOPHILIC 6-HALO-2',3'-DIDEOXYPURINE NUCLEOSIDES
MURAKAMI, K, SHIRASAKA, T, YOSHIOKA, H, KOJIMA, E, AOKI, S, FORD, H, DRISCOLL, JS, KELLEY, JA, MITSUYA, H
Published in Journal of medicinal chemistry (01.05.1991)
Published in Journal of medicinal chemistry (01.05.1991)
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Journal Article
Lipophilic, Acid-Stable, Adenosine Deaminase-Activated Anti-HIV Prodrugs for Central Nervous System Delivery. 2. 6-Halo- and 6-Alkoxy Prodrugs of 2'-.beta.-Fluoro-2',3'-dideoxyinosine
Ford, Harry, Siddiqui, Maqbool, Driscoll, John S, Marquez, Victor E, Kelley, James A, Mitsuya, Hiroaki, Shirasaka, Takuma
Published in Journal of medicinal chemistry (01.03.1995)
Published in Journal of medicinal chemistry (01.03.1995)
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Journal Article
Lipophilic, Acid-Stable, Adenosine Deaminase-Activated Anti-HIV Prodrugs for Central Nervous System Delivery. 3. 6-Amino Prodrugs of 2‘-β-Fluoro-2‘,3‘-dideoxyinosine
Driscoll, John S, Siddiqui, Maqbool A, Ford, Harry, Kelley, James A, Roth, Jeri S, Mitsuya, Hiroaki, Tanaka, Masatoshi, Marquez, Victor E
Published in Journal of medicinal chemistry (12.04.1996)
Published in Journal of medicinal chemistry (12.04.1996)
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Journal Article
The "β-Fluorine Effect" in the Non-Metal Hydride Radical Deoxygenation of Fluorine-Containing Nucleoside Xanthates
Siddiqui, Maqbool A., Driscoll, John S., Abushanab, Elie, Kelley, James A., Barchi, Joseph J., Marquez, Victor E.
Published in Nucleosides, nucleotides & nucleic acids (01.01.2000)
Published in Nucleosides, nucleotides & nucleic acids (01.01.2000)
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Journal Article
Cyclopentenylcytosine. A carbocyclic nucleoside with antitumor and antiviral properties
Marquez, Victor E, Lim, Mu Ill, Treanor, Susan P, Plowman, Jacqueline, Priest, Matthew A, Markovac, Anica, Khan, M. Sami, Kaskar, Bashir, Driscoll, John S
Published in Journal of medicinal chemistry (01.09.1988)
Published in Journal of medicinal chemistry (01.09.1988)
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