Pseudopterosin synthesis from a chiral cross-conjugated hydrocarbon through a series of cycloadditions
Newton, Christopher G., Drew, Samuel L., Lawrence, Andrew L., Willis, Anthony C., Paddon-Row, Michael N., Sherburn, Michael S.
Published in Nature chemistry (01.01.2015)
Published in Nature chemistry (01.01.2015)
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Journal Article
Total Synthesis of Kingianins A, D, and F
Drew, Samuel L., Lawrence, Andrew L., Sherburn, Michael S.
Published in Angewandte Chemie International Edition (08.04.2013)
Published in Angewandte Chemie International Edition (08.04.2013)
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Journal Article
Total Synthesis of KingianinsA, D, and F
Drew, Samuel L., Lawrence, Andrew L., Sherburn, Michael S.
Published in Angewandte Chemie International Edition (08.04.2013)
Published in Angewandte Chemie International Edition (08.04.2013)
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Journal Article
Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73
Beatty, Joel W, Lindsey, Erick A, Thomas-Tran, Rhiannon, Debien, Laurent, Mandal, Debashis, Jeffrey, Jenna L, Tran, Anh T, Fournier, Jeremy, Jacob, Steven D, Yan, Xuelei, Drew, Samuel L, Ginn, Elaine, Chen, Ada, Pham, Amber T, Zhao, Sharon, Jin, Lixia, Young, Stephen W, Walker, Nigel P, Leleti, Manmohan Reddy, Moschütz, Susanne, Sträter, Norbert, Powers, Jay P, Lawson, Kenneth V
Published in Journal of medicinal chemistry (23.04.2020)
Published in Journal of medicinal chemistry (23.04.2020)
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Journal Article
Discovery of Potent and Selective PI3Kγ Inhibitors
Drew, Samuel L, Thomas-Tran, Rhiannon, Beatty, Joel W, Fournier, Jeremy, Lawson, Kenneth V, Miles, Dillon H, Mata, Guillaume, Sharif, Ehesan U, Yan, Xuelei, Mailyan, Artur K, Ginn, Elaine, Chen, Jie, Wong, Kent, Soni, Divyank, Dhanota, Puja, Chen, Pei-Yu, Shaqfeh, Stefan G, Meleza, Cesar, Pham, Amber T, Chen, Ada, Zhao, Xiaoning, Banuelos, Jesus, Jin, Lixia, Schindler, Ulrike, Walters, Matthew J, Young, Stephen W, Walker, Nigel P, Leleti, Manmohan Reddy, Powers, Jay P, Jeffrey, Jenna L
Published in Journal of medicinal chemistry (08.10.2020)
Published in Journal of medicinal chemistry (08.10.2020)
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Journal Article
Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ)
Mata, Guillaume, Miles, Dillon H, Drew, Samuel L, Fournier, Jeremy, Lawson, Kenneth V, Mailyan, Artur K, Sharif, Ehesan U, Yan, Xuelei, Beatty, Joel W, Banuelos, Jesus, Chen, Jie, Ginn, Elaine, Chen, Ada, Gerrick, Kimberline Y, Pham, Amber T, Wong, Kent, Soni, Divyank, Dhanota, Puja, Shaqfeh, Stefan G, Meleza, Cesar, Narasappa, Nell, Singh, Hema, Zhao, Xiaoning, Jin, Lixia, Schindler, Ulrike, Walters, Matthew J, Young, Stephen W, Walker, Nigel P, Leleti, Manmohan Reddy, Powers, Jay P, Jeffrey, Jenna L
Published in Journal of medicinal chemistry (27.01.2022)
Published in Journal of medicinal chemistry (27.01.2022)
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Journal Article
Discovery of Potent and Selective 7‑Azaindole Isoindolinone-Based PI3Kγ Inhibitors
Miles, Dillon H, Yan, Xuelei, Thomas-Tran, Rhiannon, Fournier, Jeremy, Sharif, Ehesan U, Drew, Samuel L, Mata, Guillaume, Lawson, Kenneth V, Ginn, Elaine, Wong, Kent, Soni, Divyank, Dhanota, Puja, Shaqfeh, Stefan G, Meleza, Cesar, Chen, Ada, Pham, Amber T, Park, Timothy, Swinarski, Debbie, Banuelos, Jesus, Schindler, Ulrike, Walters, Matthew J, Walker, Nigel P, Zhao, Xiaoning, Young, Stephen W, Chen, Jie, Jin, Lixia, Leleti, Manmohan Reddy, Powers, Jay P, Jeffrey, Jenna L
Published in ACS medicinal chemistry letters (12.11.2020)
Published in ACS medicinal chemistry letters (12.11.2020)
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Journal Article
Total Synthesis of a Dimeric Thymol Derivative Isolated from Arnica sachalinensis
De Silvestro, Irene, Drew, Samuel L., Nichol, Gary S., Duarte, Fernanda, Lawrence, Andrew L.
Published in Angewandte Chemie (06.06.2017)
Published in Angewandte Chemie (06.06.2017)
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Journal Article
Total Synthesis of Kingianins A, D, and F
Drew, Samuel L., Lawrence, Andrew L., Sherburn, Michael S.
Published in Angewandte Chemie (08.04.2013)
Published in Angewandte Chemie (08.04.2013)
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Journal Article
Abstract 1206: Discovery and characterization of AB521, a novel, potent, and selective hypoxia-inducible factor (HIF)-2α inhibitor
Lawson, Kenneth V., Gauthier, Kelsey E. Sivick, Mailyan, Artur K., Fournier, Jeremy T., Beatty, Joel W., Drew, Samuel L., Kalisiak, Jarek, Gal, Balint, Mata, Guillaume, Wang, Zhang, Yan, Xuelei, Jin, Lixia, Ginn, Elaine, Piovesan, Dana, Au, Jennifer, Meleza, Cesar A., Young, Stephen W., Walters, Matthew J., Leleti, Manmohan, Powers, Jay P.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract C050: A novel, potent, and selective hypoxia-inducible factor (HIF)-2α antagonist
Gauthier, Kelsey E Sivick, Lawson, Kenneth V, Piovesan, Dana, Walters, Matthew J, Chen, Ada, Zhao, Xiaoning, Meleza, Cesar, Kimura, Nikki, Park, Tim, Young, Steve, Tran, Anh, Drew, Samuel L, Jin, Lixia, Leleti, Manmohan, Ginn, Elaine, Powers, Jay P
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
Abstract P206: AB521 potently and selectively inhibits pro-tumorigenic gene transcription by Hypoxia-Inducible Factor (HIF)-2α in vitro and in vivo
Gauthier, Kelsey E. Sivick, Piovesan, Dana, Cho, Soonweng, Lawson, Kenneth V., Schweickert, Patrick G., Lopez, Alejandra, Liu, Suan, Park, Timothy, Mailyan, Artur, Fournier, Jeremy T. A., Beatty, Joel W., Drew, Samuel L., Kalisiak, Jarek, Gal, Balint, Mata, Guillaume, Wang, Zhang, Rosen, Brandon R., Hardman, Clayton, Epplin, Matthaw P., Yu, Kai, Haelsig, Karl T., Jin, Lixia, Ginn, Elaine, Au, Jennie, Meleza, Cesar A., Tencer, Joel, Pham, Amber, Kwon, Hyock J., Young, Stephen W., Leleti, Manmohan, Powers, Jay P., Walters, Matthew J.
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Journal Article
Total Synthesis of Kingianins A, D, and F
Drew, Samuel L., Lawrence, Andrew L., Sherburn, Michael S.
Published in Angewandte Chemie (08.04.2013)
Published in Angewandte Chemie (08.04.2013)
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Journal Article