The evolution of thalidomide and its IMiD derivatives as anticancer agents
Bartlett, J. Blake, Dredge, Keith, Dalgleish, Angus G
Published in Nature reviews. Cancer (01.04.2004)
Published in Nature reviews. Cancer (01.04.2004)
Get full text
Journal Article
PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models
Dredge, K, Hammond, E, Handley, P, Gonda, T J, Smith, M T, Vincent, C, Brandt, R, Ferro, V, Bytheway, I
Published in British journal of cancer (15.02.2011)
Published in British journal of cancer (15.02.2011)
Get full text
Journal Article
The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy
Dredge, K., Hammond, E., Davis, K., Li, C. P., Liu, L., Johnstone, K., Handley, P., Wimmer, N., Gonda, T. J., Gautam, A., Ferro, V., Bytheway, I.
Published in Investigational new drugs (01.06.2010)
Published in Investigational new drugs (01.06.2010)
Get full text
Journal Article
Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects
DREDGE, K, MARRIOTT, J. B, MACDONALD, C. D, MAN, H-W, CHEN, R, MULLER, G. W, STIRLING, D, DALGLEISH, A. G
Published in British journal of cancer (04.11.2002)
Published in British journal of cancer (04.11.2002)
Get full text
Journal Article
Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers
BARTLETT, J. B, MICHAE, A, ZELDIS, J, DALGLEISH, A. G, CLARKE, I. A, DREDGE, K, NICHOLSON, S, KRISTELEIT, H, POLYCHRONIS, A, PANDHA, H, MULLER, G. W, STIRLING, Dl
Published in British journal of cancer (08.03.2004)
Published in British journal of cancer (08.03.2004)
Get full text
Journal Article
Thalidomide and its analogues have distinct and opposing effects on TNF‐α and TNFR2 during co‐stimulation of both CD4+ and CD8+ T cells
MARRIOTT, J. B., CLARKE, I. A., DREDGE, K., MULLER, G., STIRLING, D., DALGLEISH, A. G.
Published in Clinical and experimental immunology (01.10.2002)
Published in Clinical and experimental immunology (01.10.2002)
Get full text
Journal Article
Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity
Dredge, Keith, Marriott, J. Blake, Todryk, Stephen M, Muller, George W, Chen, Roger, Stirling, David I, Dalgleish, Angus G
Published in The Journal of immunology (1950) (15.05.2002)
Published in The Journal of immunology (1950) (15.05.2002)
Get full text
Journal Article
The dual angiogenesis/metastasis inhibitor PG545 inhibits growth factor-induced cell migration and invasion in vitro and tumor growth in vivo of ovarian cancer cells
Giri, S, Winterhoff, B, Maguire, J, Teoman, A, Dredge, K, Shridhar, V
Published in Gynecologic oncology (01.03.2012)
Published in Gynecologic oncology (01.03.2012)
Get full text
Journal Article
Adjuvants and the promotion of Th1-type cytokines in tumour immunotherapy
DREDGE, Keith, MARRIOTT, J. Blake, TODRYK, Stephen M, DALGLEISH, Angus G
Published in Cancer Immunology, Immunotherapy (01.11.2002)
Published in Cancer Immunology, Immunotherapy (01.11.2002)
Get full text
Journal Article
Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro
Dredge, Keith, Horsfall, Rebecca, Robinson, Simon P., Zhang, Ling-Hua, Lu, Ling, Tang, Yang, Shirley, Michael A., Muller, George, Schafer, Peter, Stirling, David, Dalgleish, Angus G., Bartlett, J. Blake
Published in Microvascular research (2005)
Published in Microvascular research (2005)
Get full text
Journal Article
A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins
MARRIOTT, J. Blake, CLARKE, Ian A, DALGLEISH, Angus G, CZAJKA, Anna, DREDGE, Keith, CHILDS, Kay, MAN, Hon-Wah, SCHAFER, Peter, GOVINDA, Sowmya, MULLER, George W, STIRLING, David I
Published in Cancer research (Chicago, Ill.) (01.02.2003)
Get full text
Published in Cancer research (Chicago, Ill.) (01.02.2003)
Journal Article
Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression
Harkin, Andrew, Kelly, John P, McNamara, Mairead, Connor, Thomas J, Dredge, Keith, Redmond, Anna, Leonard, Brian E
Published in European journal of pharmacology (08.01.1999)
Published in European journal of pharmacology (08.01.1999)
Get full text
Journal Article
Novel Vibrio cholerae O139 genes involved in lipopolysaccharide biosynthesis
Stroeher, U H, Parasivam, G, Dredge, B K, Manning, P A
Published in Journal of Bacteriology (01.04.1997)
Published in Journal of Bacteriology (01.04.1997)
Get full text
Journal Article
Efficacy of intramammary treatment with procaine penicillin G vs. procaine penicillin G plus neomycin in bovine clinical mastitis caused by penicillin-susceptible, gram-positive bacteria - a double blind field study
Taponen, S., Dredge, K., Henriksson, B., Pyyhtiä, A.-M., Suojala, L., Junni, R., Heinonen, K., Pyörälä, S.
Published in Journal of veterinary pharmacology and therapeutics (01.06.2003)
Published in Journal of veterinary pharmacology and therapeutics (01.06.2003)
Get full text
Journal Article