Discovery and structure-activity relationship of a series of 1-carba-1-dethiacephems exhibiting activity against methicillin-resistant Staphylococcus aureus
Ternansky, Robert J, Draheim, Susan E, Pike, Andrew J, Bell, F. William, West, Sarah J, Jordan, Christopher L, Wu, C. Y. Ernie, Preston, David A, Alborn, William
Published in Journal of medicinal chemistry (09.07.1993)
Published in Journal of medicinal chemistry (09.07.1993)
Get full text
Journal Article
Indole Inhibitors of Human Nonpancreatic Secretory Phospholipase A2. 1. Indole-3-acetamides
Dillard, Robert D., Bach, Nicholas J., Draheim, Susan E., Berry, Dennis R., Carlson, Donald G., Chirgadze, Nickolay Y., Clawson, David K., Hartley, Lawrence W., Johnson, Lea M., Jones, Noel D., McKinney, Emma R., Mihelich, Edward D., Olkowski, Jennifer L., Schevitz, Richard W., Smith, Amy C., Snyder, David W., Sommers, Cynthia D., Wery, Jean-Pierre
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
Get full text
Journal Article
Indole Inhibitors of Human Nonpancreatic Secretory Phospholipase A2. 3. Indole-3-glyoxamides
Draheim, Susan E., Bach, Nicholas J., Dillard, Robert D., Berry, Dennis R., Carlson, Donald G., Chirgadze, Nickolay Y., Clawson, David K., Hartley, Lawrence W., Johnson, Lea M., Jones, Noel D., McKinney, Emma R., Mihelich, Edward D., Olkowski, Jennifer L., Schevitz, Richard W., Smith, Amy C., Snyder, David W., Sommers, Cynthia D., Wery, Jean-Pierre
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
Get full text
Journal Article
Indole Inhibitors of Human Nonpancreatic Secretory Phospholipase A2. 2. Indole-3-acetamides with Additional Functionality
Dillard, Robert D., Bach, Nicholas J., Draheim, Susan E., Berry, Dennis R., Carlson, Donald G., Chirgadze, Nickolay Y., Clawson, David K., Hartley, Lawrence W., Johnson, Lea M., Jones, Noel D., McKinney, Emma R., Mihelich, Edward D., Olkowski, Jennifer L., Schevitz, Richard W., Smith, Amy C., Snyder, David W., Sommers, Cynthia D., Wery, Jean-Pierre
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
Get full text
Journal Article
Transgenic model for the discovery of novel human secretory non-pancreatic phospholipase A2 inhibitors
FOX, N, SONG, M, DRAHEIM, S. E, BOBBITT, J. L, FISHER, L, MIHELICH, E. D, SCHREMENTI, J, SHARP, J. D, WHITE, D. L, SNYDER, D. W, HARTLEY, L. W, CARLSON, D. G, BACH, N. J, DILLARD, R. D
Published in European journal of pharmacology (18.07.1996)
Published in European journal of pharmacology (18.07.1996)
Get full text
Journal Article
Structure-activity relationship within a series of pyrazolidinone antibacterial agents. 2. Effect of side-chain modification on in vitro activity and pharmacokinetic parameters
Ternansky, Robert J, Draheim, Susan E, Pike, Andrew J, Counter, Fred T, Eudaly, Judy A, Kasher, Jeffrey S
Published in Journal of medicinal chemistry (01.10.1993)
Published in Journal of medicinal chemistry (01.10.1993)
Get full text
Journal Article
Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI
Snyder, D W, Bach, N J, Dillard, R D, Draheim, S E, Carlson, D G, Fox, N, Roehm, N W, Armstrong, C T, Chang, C H, Hartley, L W, Johnson, L M, Roman, C R, Smith, A C, Song, M, Fleisch, J H
Published in The Journal of pharmacology and experimental therapeutics (01.03.1999)
Get full text
Published in The Journal of pharmacology and experimental therapeutics (01.03.1999)
Journal Article
Orally absorbable cephalosporin antibiotics. 2. Structure-activity studies of bicyclic glycine derivatives of 7-aminodeacetoxycephalosporanic acid
Kukolja, Stjepan, Draheim, Susan E, Graves, Bernard J, Hunden, David C, Pfeil, Janice L, Cooper, Robin D. G, Ott, John L, Counter, Fred T
Published in Journal of medicinal chemistry (01.12.1985)
Published in Journal of medicinal chemistry (01.12.1985)
Get full text
Journal Article
Orally absorbable cephalosporin antibiotics. 1. Structure-activity relationships of benzothienyl- and naphthylglycine derivatives of 7-aminodeacetoxycephalosporanic acid
Kukolja, Stjepan, Draheim, Susan E, Pfeil, Janice L, Cooper, Robin D. G, Graves, Bernard J, Holmes, Richard E, Neel, David A, Huffman, George W, Webber, J. Alan
Published in Journal of medicinal chemistry (01.12.1985)
Published in Journal of medicinal chemistry (01.12.1985)
Get full text
Journal Article
Oral absorption of cephalosporin antibiotics. 1. Synthesis, biological properties, and oral bioavailability of 7-(arylacetamido)-3-chloro cephalosporins in animals
Kukolja, S, Wright, W E, Quay, J F, Pfeil-Doyle, J, Draheim, S E, Eudaly, J A, Johnson, R J, Ott, J L, Counter, F T, Cooper, R D
Published in Journal of medicinal chemistry (01.10.1988)
Published in Journal of medicinal chemistry (01.10.1988)
Get full text
Journal Article
Orally absorbable cephalosporin antibiotics. 3. Preparation of biologically active R-isomer of 7-(3-benzothienylglycylamido)deacetoxycephalosporanic acid
Kukolja, Stjepan, Pfeil, Janice L, Draheim, Susan E, Ott, John L
Published in Journal of medicinal chemistry (01.12.1985)
Published in Journal of medicinal chemistry (01.12.1985)
Get full text
Journal Article
Indole inhibitors of human nonpancreatic secretory phospholipase A(2) .1. Indole-3-acetamides
Dillard, RD, Bach, NJ, Draheim, SE, Berry, DR, Carlson, DG, Chirgadze, NY, Clawson, DK, Hartley, LW, Johnson, LM, Jones, ND, McKinney, ER, Mihelich, ED, Olkowski, JL, Schevitz, RW, Smith, AC, Snyder, DW, Sommers, CD, Wery, JP
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
Get full text
Journal Article
Indole inhibitors of human nonpancreatic secretory phospholipase A(2) .3. Indole-3-glyoxamides
Draheim, SE, Bach, NJ, Dillard, RD, Berry, DR, Carlson, DG, Chirgadze, NY, Clawson, DK, Hartley, LW, Johnson, LM, Jones, ND, McKinney, ER, Mihelich, ED, Olkowski, JL, Schevitz, RW, Smith, AC, Snyder, DW, Sommers, CD, Wery, JP
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
Get full text
Journal Article
Structure-activity relationship within a series of pyrazolidinone antibacterial agents. II: Effect of side-chain modification on in vitro activity and pharmacokinetic parameters
TERNANSKY, R. J, DRAHEIM, S. E, PIKE, A. J, COUNTER, F. T, EUDALY, J. A, KASHER, J. S
Published in Journal of medicinal chemistry (1993)
Get full text
Published in Journal of medicinal chemistry (1993)
Journal Article
Indole inhibitors of human nonpancreatic secretory phospholipase A(2) .2. Indole-3-acetamides with additional functionality
Dillard, RD, Bach, NJ, Draheim, SE, Berry, DR, Carlson, DG, Chirgadze, NY, Clawson, DK, Hartley, LW, Johnson, LM, Jones, ND, McKinney, ER, Mihelich, ED, Olkowski, JL, Schevitz, RW, Smith, AC, Snyder, DW, Sommers, CD, Wery, JP
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
Get full text
Journal Article
Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2
Schevitz, R W, Bach, N J, Carlson, D G, Chirgadze, N Y, Clawson, D K, Dillard, R D, Draheim, S E, Hartley, L W, Jones, N D, Mihelich, E D
Published in Nature structural biology (01.06.1995)
Published in Nature structural biology (01.06.1995)
Get more information
Journal Article