Anilides of (R)-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase
Bebernitz, Gregory R, Aicher, Thomas D, Stanton, James L, Gao, Jiaping, Shetty, Suraj S, Knorr, Douglas C, Strohschein, Robert J, Tan, Jennifer, Brand, Leonard J, Liu, Charles, Wang, Wei H, Vinluan, Christine C, Kaplan, Emma L, Dragland, Carol J, DelGrande, Dominick, Islam, Amin, Lozito, Robert J, Liu, Xilin, Maniara, Wieslawa M, Mann, William R
Published in Journal of medicinal chemistry (01.06.2000)
Published in Journal of medicinal chemistry (01.06.2000)
Get full text
Journal Article
Secondary Amides of (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase
Aicher, Thomas D, Anderson, Robert C, Gao, Jiaping, Shetty, Suraj S, Coppola, Gary M, Stanton, James L, Knorr, Douglas C, Sperbeck, Donald M, Brand, Leonard J, Vinluan, Christine C, Kaplan, Emma L, Dragland, Carol J, Tomaselli, Hollis C, Islam, Amin, Lozito, Robert J, Liu, Xilin, Maniara, Wieslawa M, Fillers, William S, DelGrande, Dominick, Walter, R. Eric, Mann, William R
Published in Journal of medicinal chemistry (27.01.2000)
Published in Journal of medicinal chemistry (27.01.2000)
Get full text
Journal Article
Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex. Identification of important amino acid residues
Jackson, J C, Vinluan, C C, Dragland, C J, Sundararajan, V, Yan, B, Gounarides, J S, Nirmala, N R, Topiol, S, Ramage, P, Blume, J E, Aicher, T D, Bell, P A, Mann, W R
Published in Biochemical journal (15.09.1998)
Published in Biochemical journal (15.09.1998)
Get full text
Journal Article
Inhibition of cyclic AMP-dependent protein kinase-induced changes in the kinetic properties of hepatic pyruvate kinase by the specific cyclic AMP antagonist, the (Rp)-diastereomer of adenosine cyclic 3',5'-phosphorothioate
Dragland-Meserve, C J, Rothermel, J D, Houlihan, M J, Botelho, L H
Published in Journal of cyclic nucleotide and protein phosphorylation research (1985)
Get more information
Published in Journal of cyclic nucleotide and protein phosphorylation research (1985)
Journal Article
(R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvate dehydrogenase kinase
Aicher, TD, Anderson, RC, Bebernitz, GR, Coppola, GM, Jewell, CF, Knorr, DC, Liu, C, Sperbeck, DM, Brand, LJ, Strohschein, RJ, Gao, JP, Vinluan, CC, Shetty, SS, Dragland, C, Kaplan, EL, DelGrande, D, Islam, A, Liu, XL, Lozito, RJ, Maniara, WM, Walter, RE, Mann, WR
Published in Journal of medicinal chemistry (29.07.1999)
Published in Journal of medicinal chemistry (29.07.1999)
Get full text
Journal Article
(R)-3,3,3-trifluoro-2-hydroxy-2-methyl-propionamides are orally active inhibitors of pyruvate dehydrogenase kinase
AICHER, T. D, ANDERSON, R. C, JIANPING GAO, VINLUAN, C. C, SHETTY, S. S, DRAGLAND, C, KAPLAN, E. L, DELGRANDE, D, ISLAM, A, XILIN LIU, LOZITO, R. J, MANIARA, W. M, BEBERNITZ, G. R, WALTER, R. E, MANN, W. R, COPPOLA, G. M, JEWELL, C. F, KNORR, D. C, LIU, C, SPERBECK, D. M, BRAND, L. J, STROHSCHEIN, R. J
Published in Journal of medicinal chemistry (1999)
Get full text
Published in Journal of medicinal chemistry (1999)
Journal Article
(R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase
Aicher, Thomas D, Anderson, Robert C, Bebernitz, Gregory R, Coppola, Gary M, Jewell, Charles F, Knorr, Douglas C, Liu, Charles, Sperbeck, Donald M, Brand, Leonard J, Strohschein, Robert J, Gao, Jiaping, Vinluan, Christine C, Shetty, Suraj S, Dragland, Carol, Kaplan, Emma L, DelGrande, Dominick, Islam, Amin, Liu, Xilin, Lozito, Robert J, Maniara, Wieslawa M, Walter, R. Erik, Mann, William R
Published in Journal of medicinal chemistry (29.07.1999)
Published in Journal of medicinal chemistry (29.07.1999)
Get full text
Journal Article