Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy
Whitmore, S. Scott, Sohn, Elliott H., Chirco, Kathleen R., Drack, Arlene V., Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.
Published in Progress in retinal and eye research (01.03.2015)
Published in Progress in retinal and eye research (01.03.2015)
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Effect of an intravitreal antisense oligonucleotide on vision in Leber congenital amaurosis due to a photoreceptor cilium defect
Cideciyan, Artur V., Jacobson, Samuel G., Drack, Arlene V., Ho, Allen C., Charng, Jason, Garafalo, Alexandra V., Roman, Alejandro J., Sumaroka, Alexander, Han, Ian C., Hochstedler, Maria D., Pfeifer, Wanda L., Sohn, Elliott H., Taiel, Magali, Schwartz, Michael R., Biasutto, Patricia, Wit, Wilma de, Cheetham, Michael E., Adamson, Peter, Rodman, David M., Platenburg, Gerard, Tome, Maria D., Balikova, Irina, Nerinckx, Fanny, Zaeytijd, Julie De, Van Cauwenbergh, Caroline, Leroy, Bart P., Russell, Stephen R.
Published in Nature medicine (01.02.2019)
Published in Nature medicine (01.02.2019)
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Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet–Biedl syndrome
Datta, Poppy, Allamargot, Chantal, Hudson, Joseph S., Andersen, Emily K., Bhattarai, Sajag, Drack, Arlene V., Sheffield, Val C., Seo, Seongjin
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
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AAV2/4-RS1 gene therapy in the retinoschisin knockout mouse model of X-linked retinoschisis
Scruggs, Brittni A, Bhattarai, Sajag, Helms, Megan, Cherascu, Ioana, Salesevic, Adisa, Stalter, Elliot, Laird, Joseph, Baker, Sheila A, Drack, Arlene V
Published in PloS one (07.12.2022)
Published in PloS one (07.12.2022)
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Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases
Wiley, Luke A., Burnight, Erin R., Songstad, Allison E., Drack, Arlene V., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A.
Published in Progress in retinal and eye research (01.01.2015)
Published in Progress in retinal and eye research (01.01.2015)
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Journal Article
Progressive retinal degeneration of rods and cones in a Bardet-Biedl syndrome type 10 mouse model
Mayer, Sara K, Thomas, Jacintha, Helms, Megan, Kothapalli, Aishwarya, Cherascu, Ioana, Salesevic, Adisa, Stalter, Elliot, Wang, Kai, Datta, Poppy, Searby, Charles, Seo, Seongjin, Hsu, Ying, Bhattarai, Sajag, Sheffield, Val C, Drack, Arlene V
Published in Disease models & mechanisms (01.09.2022)
Published in Disease models & mechanisms (01.09.2022)
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Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa
Tucker, Budd A, Mullins, Robert F, Streb, Luan M, Anfinson, Kristin, Eyestone, Mari E, Kaalberg, Emily, Riker, Megan J, Drack, Arlene V, Braun, Terry A, Stone, Edwin M
Published in eLife (27.08.2013)
Published in eLife (27.08.2013)
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Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq
Whitmore, S. Scott, Wagner, Alex H., DeLuca, Adam P., Drack, Arlene V., Stone, Edwin M., Tucker, Budd A., Zeng, Shemin, Braun, Terry A., Mullins, Robert F., Scheetz, Todd E.
Published in Experimental eye research (01.12.2014)
Published in Experimental eye research (01.12.2014)
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Journal Article
Subretinal gene therapy delays vision loss in a Bardet-Biedl Syndrome type 10 mouse model
Hsu, Ying, Bhattarai, Sajag, Thompson, Jacob M., Mahoney, Angela, Thomas, Jacintha, Mayer, Sara K., Datta, Poppy, Garrison, Janelle, Searby, Charles C., Vandenberghe, Luk H., Seo, Seongjin, Sheffield, Val C., Drack, Arlene V.
Published in Molecular therapy. Nucleic acids (14.03.2023)
Published in Molecular therapy. Nucleic acids (14.03.2023)
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Journal Article
TUDCA slows retinal degeneration in two different mouse models of retinitis pigmentosa and prevents obesity in Bardet-Biedl syndrome type 1 mice
Drack, Arlene V, Dumitrescu, Alina V, Bhattarai, Sajag, Gratie, Daniel, Stone, Edwin M, Mullins, Robert, Sheffield, Val C
Published in Investigative ophthalmology & visual science (05.01.2012)
Published in Investigative ophthalmology & visual science (05.01.2012)
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A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes
Swier, Vicki J, White, Katherine A, Johnson, Tyler B, Wang, Xiaojun, Han, Jimin, Pearce, David A, Singh, Ruchira, Drack, Arlene V, Pfeifer, Wanda, Rogers, Christopher S, Brudvig, Jon J, Weimer, Jill M
Published in Disease models & mechanisms (01.08.2023)
Published in Disease models & mechanisms (01.08.2023)
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Investigating the role of Caspase-1 in a mouse model of Juvenile X-linked Retinoschisis
Gehrke, Ella J, Pandey, Araniko, Thompson, Jacob, Bhattarai, Sajag, Gurung, Prajwal, Hsu, Ying, Drack, Arlene V
Published in Frontiers in medicine (13.06.2024)
Published in Frontiers in medicine (13.06.2024)
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RNA interference-based therapy for spinocerebellar ataxia type 7 retinal degeneration
Ramachandran, Pavitra S, Bhattarai, Sajag, Singh, Pratibha, Boudreau, Ryan L, Thompson, Stewart, Laspada, Albert R, Drack, Arlene V, Davidson, Beverly L
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene Augmentation-Based Strategy to Treat CLN3-Associated Retinal Degeneration
Wiley, Luke A, Burnight, Erin R, Drack, Arlene V, Banach, Bailey B, Ochoa, Dalyz, Cranston, Cathryn M, Madumba, Robert A, East, Jade S, Mullins, Robert F, Stone, Edwin M, Tucker, Budd A
Published in Human gene therapy (01.10.2016)
Published in Human gene therapy (01.10.2016)
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Journal Article
The dose-response relationship of subretinal gene therapy with rAAV2tYF-CB-hRS1 in a mouse model of X-linked retinoschisis
Hassan, Salma, Hsu, Ying, Thompson, Jacob M., Kalmanek, Emily, VandeLune, Joel A., Stanley, Sarah, Drack, Arlene V.
Published in Frontiers in medicine (13.02.2024)
Published in Frontiers in medicine (13.02.2024)
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Journal Article
Endothelial BBSome is essential for vascular, metabolic, and retinal functions
Jiang, Jingwei, Reho, John J., Bhattarai, Sajag, Cherascu, Ioana, Hedberg-Buenz, Adam, Meyer, Kacie J., Tayyari, Fariba, Rauckhorst, Adam J., Guo, Deng Fu, Morgan, Donald A., Taylor, Eric B., Anderson, Michael G., Drack, Arlene V., Rahmouni, Kamal
Published in Molecular metabolism (Germany) (01.11.2021)
Published in Molecular metabolism (Germany) (01.11.2021)
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Journal Article
Nanophthalmos patient with a THR518MET mutation in MYRF, a case report
Hagedorn, Joshua, Avdic, Armin, Schnieders, Michael J, Roos, Benjamin R, Kwon, Young H, Drack, Arlene V, Boese, Erin A, Fingert, John H
Published in BMC ophthalmology (01.10.2020)
Published in BMC ophthalmology (01.10.2020)
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Journal Article
Long-term functional and structural outcomes in X-linked retinoschisis: implications for clinical trials
Fenner, Beau J, Russell, Jonathan F, Drack, Arlene V, Dumitrescu, Alina V, Sohn, Elliott H, Russell, Stephen R, Boldt, H Culver, Affatigato, Louisa M, Hoffmann, Jeremy M, Andorf, Jeaneen L, Stone, Edwin M, Han, Ian C
Published in Frontiers in medicine (15.06.2023)
Published in Frontiers in medicine (15.06.2023)
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