A study on redox reactions of the azo dye Sudan I and its hydroxylated metabolites on pyrolytic graphite and boron doped diamond electrodes to support electrochemical studies of metabolic transformations
Ondráčková, Anna, Stiborová, Marie, Dračínská, Helena, Havran, Luděk, Schwarzová-Pecková, Karolina, Fojta, Miroslav
Published in Electrochimica acta (10.11.2023)
Published in Electrochimica acta (10.11.2023)
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The tyrosine kinase inhibitor lenvatinib is oxidized by rat cytochromes P450 and affects their expression in rat liver
Indra, Radek, Jelínková, Sandra, Kollárová, Katarína, Zahumenská, Petra, Dvořák, Josef, Dušková, Šárka, Dračínská, Helena
Published in Acta pharmaceutica (Zagreb, Croatia) (01.09.2024)
Published in Acta pharmaceutica (Zagreb, Croatia) (01.09.2024)
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Benzo[ a ]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
Dračínská, Helena, Indra, Radek, Jelínková, Sandra, Černá, Věra, Arlt, Volker Manfred, Stiborová, Marie
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
Dračínská, Helena, Bárta, František, Levová, Kateřina, Hudecová, Alena, Moserová, Michaela, Schmeiser, Heinz H, Kopka, Klaus, Frei, Eva, Arlt, Volker M, Stiborová, Marie
Published in Toxicology (Amsterdam) (17.02.2016)
Published in Toxicology (Amsterdam) (17.02.2016)
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Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats
Stiborová, Marie, Dračínská, Helena, Bořek-Dohalská, Lucie, Klusoňová, Zuzana, Holecová, Jana, Martínková, Markéta, Schmeiser, Heinz H., Arlt, Volker M.
Published in Toxicology (Amsterdam) (01.05.2018)
Published in Toxicology (Amsterdam) (01.05.2018)
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Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1‑Phenylazo-2-naphthol (Sudan I)
Stiborová, Marie, Dračínská, Helena, Martínek, Václav, Svášková, Dagmar, Hodek, Petr, Milichovský, Jan, Hejduková, Žaneta, Brotánek, Jaroslav, Schmeiser, Heinz H, Frei, Eva
Published in Chemical research in toxicology (18.02.2013)
Published in Chemical research in toxicology (18.02.2013)
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Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450
Dracínska, Helena, Miksanová, Markéta, Svobodová, Martina, Smrcek, Stanislav, Frei, Eva, Schmeiser, Heinz H, Stiborová, Marie
Published in Neuro-endocrinology letters (01.12.2006)
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Published in Neuro-endocrinology letters (01.12.2006)
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Photo-initiated crosslinking extends mapping of the protein-protein interface to membrane-embedded portions of cytochromes P450 2B4 and b
Ječmen, Tomáš, Ptáčková, Renata, Černá, Věra, Dračínská, Helena, Hodek, Petr, Stiborová, Marie, Hudeček, Jiří, Šulc, Miroslav
Published in Methods (San Diego, Calif.) (01.11.2015)
Published in Methods (San Diego, Calif.) (01.11.2015)
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Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats
Mizerovská, Jana, Dračínská, Helena, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Stiborová, Marie
Published in Mutation research (28.02.2011)
Published in Mutation research (28.02.2011)
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Journal Article
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity
Stiborová, Marie, Dračínská, Helena, Mizerovská, Jana, Frei, Eva, Schmeiser, Heinz H, Hudeček, Jiří, Hodek, Petr, Phillips, David H, Arlt, Volker M
Published in Toxicology (Amsterdam) (02.05.2008)
Published in Toxicology (Amsterdam) (02.05.2008)
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THE ENVIRONMENTAL POLLUTANT AND CARCINOGEN 3-NITROBENZANTHRONE AND ITS HUMAN METABOLITE 3-AMINOBENZANTHRONE ARE POTENT INDUCERS OF RAT HEPATIC CYTOCHROMES P450 1A1 AND -1A2 AND NAD(P)H:QUINONE OXIDOREDUCTASE
STIBOROVA, Marie, DRACINSKA, Helena, HAJKOVA, Jana, KADEVRABKOVA, Pavla, FREI, Eva, SCHMEISER, Heinz H, SOUCEK, Pavel, PHILLIPS, David H, ARIT, Volker M
Published in Drug metabolism and disposition (01.08.2006)
Published in Drug metabolism and disposition (01.08.2006)
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Redox Cycling in the Metabolism of the Environmental Pollutant and Suspected Human Carcinogen o-Anisidine by Rat and Rabbit Hepatic Microsomes
Naiman, Karel, Dračínská, Helena, Martínková, Markéta, Šulc, Miroslav, Dračínský, Martin, Kejíková, Lucie, Hodek, Petr, Hudeček, Jirí, Liberda, Jirí, Schmeiser, Heinz H, Frei, Eva, Stiborová, Marie
Published in Chemical research in toxicology (01.08.2008)
Published in Chemical research in toxicology (01.08.2008)
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Induced expression of microsomal cytochrome b5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)
Stiborová, Marie, Moserová, Michaela, Mrízová, Iveta, Dračínská, Helena, Martínek, Václav, Indra, Radek, Frei, Eva, Adam, Vojtěch, Kizek, René, Schmeiser, Heinz H., Kubáčková, Kateřina, Arlt, Volker M.
Published in Monatshefte für Chemie (2016)
Published in Monatshefte für Chemie (2016)
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3-Aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung
Stiborová, Marie, Dračínská, Helena, Martínková, Markéta, Mizerovská, Jana, Hudeček, Jiří, Hodek, Petr, Liberda, Jiří, Frei, Eva, Schmeiser, Heinz H., Phillips, David H., Arlt, Volker M.
Published in Mutation research (31.05.2009)
Published in Mutation research (31.05.2009)
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Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 - similarity between human and rat enzymes
Svobodová, Martina, Dračínská, Helena, Martínková, Markéta, Hudeček, Jiří, Hodek, Petr, Frei, Eva, Stiborová, Marie
Published in Interdisciplinary toxicology (01.09.2008)
Published in Interdisciplinary toxicology (01.09.2008)
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Journal Article
Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone
Mizerovská, Jana, Dračínská, Helena, Arlt, Volker, Hudeček, Jiří, Hodek, Petr, Schmeiser, Heinz, Frei, Eva, Stiborová, Marie
Published in Interdisciplinary toxicology (01.09.2008)
Published in Interdisciplinary toxicology (01.09.2008)
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Journal Article
The Anticancer Drug Ellipticine is an Inducer of Rat NAD(P)H:Quinone Oxidoreductase
Stiborová, Marie, Dračínská, Helena, Aimová, Dagmar, Hodek, Petr, Hudeček, Jiří, Ryšlavá, Helena, Schmeiser, Heinz H., Frei, Eva
Published in Collection of Czechoslovak chemical communications (01.10.2007)
Published in Collection of Czechoslovak chemical communications (01.10.2007)
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Journal Article
Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole
Naiman, Karel, Dračínská, Helena, Dračínský, Martin, Martínková, Markéta, Martínek, Václav, Hodek, Petr, Štícha, Martin, Frei, Eva, Stiborová, Marie
Published in Interdisciplinary toxicology (01.12.2008)
Published in Interdisciplinary toxicology (01.12.2008)
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Journal Article
Benzoapyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
Dračínská, Helena, Indra, Radek, Jelínková, Sandra, Černá, Věra, Arlt, Volker Manfred, Stiborová, Marie
Published in International journal of molecular sciences (28.07.2021)
Published in International journal of molecular sciences (28.07.2021)
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Journal Article
Photo-initiated crosslinking extends mapping of the protein–protein interface to membrane-embedded portions of cytochromes P450 2B4 and b5
Ječmen, Tomáš, Ptáčková, Renata, Černá, Věra, Dračínská, Helena, Hodek, Petr, Stiborová, Marie, Hudeček, Jiří, Šulc, Miroslav
Published in Methods (San Diego, Calif.) (01.11.2015)
Published in Methods (San Diego, Calif.) (01.11.2015)
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