Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer
O'Neill, Luke A J, Bryant, Clare E, Doyle, Sarah L
Published in Pharmacological reviews (01.06.2009)
Published in Pharmacological reviews (01.06.2009)
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NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
Doyle, Sarah L, Campbell, Matthew, Ozaki, Ema, Salomon, Robert G, Mori, Andres, Kenna, Paul F, Farrar, Gwyneth Jane, Kiang, Anna-Sophia, Humphries, Marian M, Lavelle, Ed C, O'Neill, Luke A J, Hollyfield, Joe G, Humphries, Peter
Published in Nature medicine (01.05.2012)
Published in Nature medicine (01.05.2012)
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Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction
Giannoudaki, Eirini, Hernandez-Santana, Yasmina E., Mulfaul, Kelly, Doyle, Sarah L., Hams, Emily, Fallon, Padraic G., Mat, Arimin, O’Shea, Donal, Kopf, Manfred, Hogan, Andrew E., Walsh, Patrick T.
Published in Nature communications (05.09.2019)
Published in Nature communications (05.09.2019)
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Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation
Kelly, Alanna M, Leech, John M, Doyle, Sarah L, McLoughlin, Rachel M
Published in PLoS pathogens (01.07.2022)
Published in PLoS pathogens (01.07.2022)
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Journal Article
TRAM is required for TLR2 endosomal signaling to type I IFN induction
Stack, Julianne, Doyle, Sarah L, Connolly, Dympna J, Reinert, Line S, O'Keeffe, Kate M, McLoughlin, Rachel M, Paludan, Søren R, Bowie, Andrew G
Published in The Journal of immunology (1950) (15.12.2014)
Published in The Journal of immunology (1950) (15.12.2014)
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Journal Article
Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration
Mulfaul, Kelly, Ozaki, Ema, Fernando, Nilisha, Brennan, Kiva, Chirco, Kathleen R., Connolly, Emma, Greene, Chris, Maminishkis, Arvydas, Salomon, Robert G., Linetsky, Mikhail, Natoli, Riccardo, Mullins, Robert F., Campbell, Matthew, Doyle, Sarah L.
Published in Cell reports (Cambridge) (18.02.2020)
Published in Cell reports (Cambridge) (18.02.2020)
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Impact of previous pregnancy and BMI on cellular and serum immune activity from early to late pregnancy
Mealy, Grace, Brennan, Kiva, Killeen, Sarah Louise, Kilbane, Mark, Yelverton, Cara, Saldova, Radka, Groeger, David, VanSinderen, Douwe, Cotter, Paul D., Doyle, Sarah L., McAuliffe, Fionnuala M.
Published in Scientific reports (11.07.2024)
Published in Scientific reports (11.07.2024)
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Journal Article
IL-10 Inhibits miR-155 Induction by Toll-like Receptors
McCoy, Claire E., Sheedy, Frederick J., Qualls, Joseph E., Doyle, Sarah L., Quinn, Susan R., Murray, Peter J., O'Neill, Luke A.J.
Published in The Journal of biological chemistry (02.07.2010)
Published in The Journal of biological chemistry (02.07.2010)
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Journal Article
Attenuated CSF‐1R signalling drives cerebrovascular pathology
Delaney, Conor, Farrell, Michael, Doherty, Colin P, Brennan, Kiva, O’Keeffe, Eoin, Greene, Chris, Byrne, Kieva, Kelly, Eoin, Birmingham, Niamh, Hickey, Paula, Cronin, Simon, Savvides, Savvas N, Doyle, Sarah L, Campbell, Matthew
Published in EMBO molecular medicine (05.02.2021)
Published in EMBO molecular medicine (05.02.2021)
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Author Correction: Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration
Wooff, Yvette, Fernando, Nilisha, Wong, Josephine H. C., Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua A., Robertson, Avril A. B., Doyle, Sarah L., Man, Si Ming, Natoli, Riccardo
Published in Scientific reports (16.09.2024)
Published in Scientific reports (16.09.2024)
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Journal Article
Low Density Granulocytes in ANCA Vasculitis Are Heterogenous and Hypo-Responsive to Anti-Myeloperoxidase Antibodies
Ui Mhaonaigh, Aisling, Coughlan, Alice M, Dwivedi, Amrita, Hartnett, Jack, Cabral, Joana, Moran, Barry, Brennan, Kiva, Doyle, Sarah L, Hughes, Katherine, Lucey, Rosemary, Floudas, Achilleas, Fearon, Ursula, McGrath, Susan, Cormican, Sarah, De Bhailis, Aine, Molloy, Eleanor J, Brady, Gareth, Little, Mark A
Published in Frontiers in immunology (07.11.2019)
Published in Frontiers in immunology (07.11.2019)
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Journal Article
IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration
Doyle, Sarah L, Ozaki, Ema, Brennan, Kiva, Humphries, Marian M, Mulfaul, Kelly, Keaney, James, Kenna, Paul F, Maminishkis, Arvydas, Kiang, Anna-Sophia, Saunders, Sean P, Hams, Emily, Lavelle, Ed C, Gardiner, Clair, Fallon, Padraic G, Adamson, Peter, Humphries, Peter, Campbell, Matthew
Published in Science translational medicine (02.04.2014)
Published in Science translational medicine (02.04.2014)
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Journal Article
SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration
Gibbons, Luke, Ozaki, Ema, Greene, Chris, Trappe, Anne, Carty, Michael, Coppinger, Judith A, Bowie, Andrew G, Campbell, Matthew, Doyle, Sarah L
Published in Frontiers in neuroscience (01.04.2022)
Published in Frontiers in neuroscience (01.04.2022)
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Journal Article
IL-18 Immunotherapy for Neovascular AMD: Tolerability and Efficacy in Nonhuman Primates
Doyle, Sarah L, López, Francisco J, Celkova, Lucia, Brennan, Kiva, Mulfaul, Kelly, Ozaki, Ema, Kenna, Paul F, Kurali, Edit, Hudson, Natalie, Doggett, Teresa, Ferguson, Thomas A, Humphries, Peter, Adamson, Peter, Campbell, Matthew
Published in Investigative ophthalmology & visual science (01.08.2015)
Published in Investigative ophthalmology & visual science (01.08.2015)
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Journal Article
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway
Espevik, Terje, McGettrick, Anne F, O'Neill, Luke A J, Gong, Mei, Hardy, Matthew, Doyle, Sarah L, Banahan, Kathy, Palsson-McDermott, Eva M, Husebye, Harald, Golenbock, Douglas
Published in Nature immunology (01.06.2009)
Published in Nature immunology (01.06.2009)
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Journal Article
Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin
Kenny, Elaine F, Quinn, Susan R, Doyle, Sarah L, Vink, Paul M, van Eenennaam, Hans, O'Neill, Luke A J
Published in PloS one (14.08.2013)
Published in PloS one (14.08.2013)
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Journal Article
SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration
Ozaki, Ema, Gibbons, Luke, Neto, Nuno Gb, Kenna, Paul, Carty, Michael, Humphries, Marian, Humphries, Pete, Campbell, Matthew, Monaghan, Michael, Bowie, Andrew, Doyle, Sarah L
Published in Life science alliance (01.05.2020)
Published in Life science alliance (01.05.2020)
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Journal Article
MyD88 Adapter-like (Mal) Is Phosphorylated by Bruton's Tyrosine Kinase during TLR2 and TLR4 Signal Transduction
Gray, Pearl, Dunne, Aisling, Brikos, Constantinos, Jefferies, Caroline A., Doyle, Sarah L., O'Neill, Luke A.J.
Published in The Journal of biological chemistry (14.04.2006)
Published in The Journal of biological chemistry (14.04.2006)
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