Management of Metabolic Effects Associated With Anticancer Agents Targeting the PI3K-Akt-mTOR Pathway
BUSAIDY, Naifa L, FAROOKI, Azeez, DOWLATI, Afshin, PERENTESIS, John P, DANCEY, Janet E, DOYLE, Laurence A, BRELL, Joanna M, SIU, Lillian L
Published in Journal of clinical oncology (10.08.2012)
Published in Journal of clinical oncology (10.08.2012)
Get full text
Journal Article
Insulin Growth Factor-Receptor (IGF-1R) Antibody Cixutumumab Combined with the mTOR Inhibitor Temsirolimus in Patients with Refractory Ewing's Sarcoma Family Tumors
NAING, Aung, LORUSSO, Patricia, SIQING FU, HONG, David S, ANDERSON, Pete, BENJAMIN, Robert S, LUDWIG, Joseph, CHEN, Helen X, DOYLE, Laurence A, KURZROCK, Razelle
Published in Clinical cancer research (01.05.2012)
Published in Clinical cancer research (01.05.2012)
Get full text
Journal Article
A phase I trial of MK-2206 and hydroxychloroquine in patients with advanced solid tumors
Mehnert, Janice M., Kaveney, Amanda D., Malhotra, Jyoti, Spencer, Kristen, Portal, Daniella, Goodin, Susan, Tan, Antoinette R., Aisner, Joseph, Moss, Rebecca A., Lin, Hongxia, Bertino, Joseph R., Gibbon, Darlene, Doyle, Laurence A., White, Eileen P., Stein, Mark N.
Published in Cancer chemotherapy and pharmacology (01.10.2019)
Published in Cancer chemotherapy and pharmacology (01.10.2019)
Get full text
Journal Article
A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer
Ma, Cynthia X., Ellis, Matthew J. C., Petroni, Gina R., Guo, Zhanfang, Cai, Shi-rong, Ryan, Christine E., Craig Lockhart, A., Naughton, Michael J., Pluard, Timothy J., Brenin, Christiana M., Picus, Joel, Creekmore, Allison N., Mwandoro, Tibu, Yarde, Erin R., Reed, Jerry, Ebbert, Mark, Bernard, Philip S., Watson, Mark, Doyle, Laurence A., Dancey, Janet, Piwnica-Worms, Helen, Fracasso, Paula M.
Published in Breast cancer research and treatment (01.01.2013)
Published in Breast cancer research and treatment (01.01.2013)
Get full text
Journal Article
SU2C phase Ib study of paclitaxel and MK-2206 in advanced solid tumors and metastatic breast cancer
Gonzalez-Angulo, Ana M, Krop, Ian, Akcakanat, Argun, Chen, Huiqin, Liu, Shuying, Li, Yisheng, Culotta, Kirk S, Tarco, Emily, Piha-Paul, Sarina, Moulder-Thompson, Stacy, Velez-Bravo, Vivianne, Sahin, Aysegul A, Doyle, Laurence A, Do, Kim-Anh, Winer, Eric P, Mills, Gordon B, Kurzrock, Razelle, Meric-Bernstam, Funda
Published in JNCI : Journal of the National Cancer Institute (01.03.2015)
Published in JNCI : Journal of the National Cancer Institute (01.03.2015)
Get full text
Journal Article
Phase II study of copanlisib in patients with tumors with PIK3CA mutations ( PTEN loss allowed): NCI MATCH EAY131-Z1F
Damodaran, Senthil, Zhao, Fengmin, Deming, Dustin A., Mitchell, Edith P., Wright, John Joseph, Doyle, Laurence A, Gray, Robert James, Li, Shuli, McShane, Lisa, Rubinstein, Larry V, Patton, David R, Williams, Mickey, Hamilton, Stanley R., Suga, Jennifer Marie, Conley, Barbara A., Arteaga, Carlos L., Harris, Lyndsay, O'Dwyer, Peter J., Chen, Alice P., Flaherty, Keith
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
Get full text
Journal Article
Phase II Study of the MEK 1/2 inhibitor selumetinib (AZD6244, ARRY-142886) in children with neurofibromatosis type 1 (NF1) and inoperable plexiform neurofibromas (PN)
Gross, Andrea M, Baldwin, Andrea, Dombi, Eva, Wolters, Pamela, Whitcomb, Patricia, Holmblad, Marielle, Martin, Staci, Fisher, Michael J., Kim, AeRang, Weiss, Brian D., Paul, Scott M., Clapp, Wade, Farrell, Kathleen, Smith, Michaele, Fontana, Joseph, Brofferio, Alessandra, Steinberg, Seth M., Doyle, Laurence A, Widemann, Brigitte C.
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
Get full text
Journal Article
Temsirolimus (TEM) and lenalidomide (LEN) in relapsed/refractory Hodgkin lymphoma including in patients with prior exposure to brentuximab vedotin (BV)
Jasielec, Jagoda, Kimball, Amy Sarah, Cohen, Kenneth Stuart, Kline, Justin Paul, Rapoport, Aaron, Petrich, Adam Matthew, Nabhan, Chadi, Thomas, Sachdev, Doyle, Laurence A., Stadler, Walter Michael, Karrison, Theodore, Smith, Sonali M.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
Get full text
Journal Article
LGG-08. A PHASE II PROSPECTIVE STUDY OF SELUMETINIB IN CHILDREN WITH RECURRENT OR REFRACTORY LOW-GRADE GLIOMA (LGG): A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY
Fangusaro, Jason, Onar-Thomas, Arzu, Poussaint, Tina Y, Wu, Shengjie, Ligon, Azra H, Lindeman, Neal, Banerjee, Anu, Packer, Roger J, Kilburn, Lindsay B, Pollack, Ian F, Jakacki, Regina I, Qaddoumi, Ibrahim, Fisher, Paul G, Dhall, Girish, Baxter, Patricia, Kreissman, Susan G, Stewart, Clinton F, Pfister, Stefan M, Jones, David TW, Vezina, Gilbert, Stern, Jessica, Panigrahy, Ashok, Jones, Blaise V, Patay, Zoltan, Tamrazi, Benita, Jones, Jeremy Y, Haque, Sofia S, Enterline, David S, Cha, Soonmee, Doyle, Laurence A, Smith, Malcolm, Boyett, James M, Dunkel, Ira J, Fouladi, Maryam
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Get full text
Journal Article
Phase I trial of temsirolimus and lenalidomide in pts with rel/ref lymphomas
Smith, Sonali M., Cohen, Kenneth Stuart, Kline, Justin Paul, Zavala, Jose D, Conner, Kathy, Thomas, Sachdev P, Lesho, Patricia, Doyle, Laurence A., Stadler, Walter Michael, Karrison, Theodore, Kimball, Amy Sarah
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
Get full text
Journal Article
A phase I, single-institution, open-label, dose escalation trial with an expansion cohort evaluating the safety and tolerability of AZD6244 and IMC-A12 in subjects with advanced solid malignancies
Ahmed, Shabina Roohi, Ball, Douglas Wilmot, Cosgrove, David, Scardina, Angela, Petito, Emily, Downs, Melinda, Nelkin, Barry, Chen, Helen X., Doyle, Laurence A, Donehower, Ross C., Carducci, Michael Anthony, Azad, Nilofer Saba
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
Get full text
Journal Article
Pharmacodynamic biomarker-driven trial of MK-2206, an AKT inhibitor, with AZD6244 (selumetinib), a MEK inhibitor, in patients with advanced colorectal carcinoma (CRC)
Speranza, Giovanna, Kinders, Robert J., Khin, Sonny, Weil, Marcie K., Do, Khanh Tu, Horneffer, Yvonne, Juwara, Lamin, Allen, Deborah, Williams, P. Mickey, Lih, Chih Jian, Rubinstein, Larry, Doyle, Laurence A, Doroshow, James H., Kummar, Shivaani
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
Get full text
Journal Article
A phase I study of selumetinib (AZD6244/ARRY-142866) in combination with cetuximab (cet) in refractory solid tumors and KRAS mutant colorectal cancer (CRC)
Deming, Dustin A., Schelman, William R., Lubner, Sam Joseph, Mulkerin, Daniel, LoConte, Noelle K., Fioravanti, Suzanne, Greten, Tim, Eickhoff, Jens C., Kolesar, Jill, Compton, Kathryn, Doyle, Laurence A, Wilding, George, Duffy, Austin G., Liu, Glenn
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
Get full text
Journal Article