Effects of Cannabinor, a Novel Selective Cannabinoid 2 Receptor Agonist, on Bladder Function in Normal Rats
Gratzke, Christian, Streng, Tomi, Stief, Christian G, Downs, Thomas R, Alroy, Iris, Rosenbaum, Jan S, Andersson, Karl-Erik, Hedlund, Petter
Published in European urology (01.06.2010)
Published in European urology (01.06.2010)
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Journal Article
Urothelial beta-3 adrenergic receptors in the rat bladder
Kullmann, F. Aura, Downs, Thomas R., Artim, Debra E., Limberg, Brian J., Shah, Mansi, Contract, Dan, de Groat, William C., Rosenbaum, Jan S.
Published in Neurourology and urodynamics (01.01.2011)
Published in Neurourology and urodynamics (01.01.2011)
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Validation of the 3D reconstructed human skin Comet assay, an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays
Pfuhler, Stefan, Pirow, Ralph, Downs, Thomas R, Haase, Andrea, Hewitt, Nicola, Luch, Andreas, Merkel, Marion, Petrick, Claudia, Said, André, Schäfer-Korting, Monika, Reisinger, Kerstin
Published in Mutagenesis (28.04.2021)
Published in Mutagenesis (28.04.2021)
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Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility
Reisinger, Kerstin, Blatz, Veronika, Brinkmann, Joep, Downs, Thomas R., Fischer, Anja, Henkler, Frank, Hoffmann, Sebastian, Krul, Cyrille, Liebsch, Manfred, Luch, Andreas, Pirow, Ralph, Reus, Astrid A., Schulz, Markus, Pfuhler, Stefan
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.03.2018)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.03.2018)
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Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays
Pfuhler, Stefan, Downs, Thomas R, Hewitt, Nicola J, Hoffmann, Sebastian, Mun, Greg C, Ouedraogo, Gladys, Roy, Shambhu, Curren, Rodger D, Aardema, Marilyn J
Published in Mutagenesis (28.04.2021)
Published in Mutagenesis (28.04.2021)
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Journal Article
Weak silica nanomaterial-induced genotoxicity can be explained by indirect DNA damage as shown by the OGG1-modified comet assay and genomic analysis
Pfuhler, Stefan, Downs, Thomas R, Allemang, Ashley J, Shan, Yuching, Crosby, Meredith E
Published in Mutagenesis (01.01.2017)
Published in Mutagenesis (01.01.2017)
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Journal Article
Silica nanoparticles administered at the maximum tolerated dose induce genotoxic effects through an inflammatory reaction while gold nanoparticles do not
Downs, Thomas R., Crosby, Meredith E., Hu, Ting, Kumar, Shyam, Sullivan, Ashley, Sarlo, Katherine, Reeder, Bob, Lynch, Matt, Wagner, Matthew, Mills, Tim, Pfuhler, Stefan
Published in Mutation research (14.06.2012)
Published in Mutation research (14.06.2012)
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Journal Article
Comet assay in reconstructed 3D human epidermal skin models—investigation of intra- and inter-laboratory reproducibility with coded chemicals
Reus, Astrid A., Reisinger, Kerstin, Downs, Thomas R., Carr, Gregory J., Zeller, Andreas, Corvi, Raffaella, Krul, Cyrille A.M., Pfuhler, Stefan
Published in Mutagenesis (01.11.2013)
Published in Mutagenesis (01.11.2013)
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Journal Article
Cannabinor, a Selective Cannabinoid-2 Receptor Agonist, Improves Bladder Emptying in Rats With Partial Urethral Obstruction
Gratzke, Christian, Streng, Tomi, Stief, Christian G, Alroy, Iris, Limberg, Brian J, Downs, Thomas R, Rosenbaum, Jan S, Hedlund, Petter, Andersson, Karl-Erik
Published in The Journal of urology (01.02.2011)
Published in The Journal of urology (01.02.2011)
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Journal Article
Comparison of the effects of oestrogen deficiency and old age on primary bladder afferent activity and voiding behaviour in the ageing female rat
Aizawa, Naoki, Iijima, Kazuyoshi, Rosenbaum, Jan S., Downs, Thomas R., Igawa, Yasuhiko, Andersson, Karl‐Erik, Wyndaele, Jean‐Jacques
Published in BJU international (01.07.2011)
Published in BJU international (01.07.2011)
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Journal Article
1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Klopfenstein, Sean R., Evdokimov, Artem G., Colson, Anny-Odile, Fairweather, Neil T., Neuman, Jeffrey J., Maier, Matthew B., Gray, Jeffrey L., Gerwe, Gina S., Stake, George E., Howard, Brian W., Farmer, Julie A., Pokross, Matthew E., Downs, Thomas R., Kasibhatla, Bhavani, Peters, Kevin G.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Journal Article
A nonspecific phosphotyrosine phosphatase inhibitor, bis(maltolato)oxovanadium(IV), improves glucose tolerance and prevents diabetes in Zucker diabetic fatty rats
Winter, Carol L, Lange, Jana S, Davis, Michael G, Gerwe, Gina S, Downs, Thomas R, Peters, Kevin G, Kasibhatla, Bhavani
Published in Experimental biology and medicine (Maywood, N.J.) (01.03.2005)
Published in Experimental biology and medicine (Maywood, N.J.) (01.03.2005)
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Cloning and characterization of mouse growth hormone-releasing hormone (GRH) complementary DNA: increased GRH messenger RNA levels in the growth hormone-deficient lit/lit mouse
FROHMAN, M. A, DOWNS, T. R, CHOMCZYNSKI, P, FROHMAN, L. A
Published in Molecular endocrinology (Baltimore, Md.) (01.10.1989)
Published in Molecular endocrinology (Baltimore, Md.) (01.10.1989)
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Journal Article
Comparison of high throughput screening technologies for luminescence cell-based reporter screens
Davis, Gregory F, Downs, Thomas R, Farmer, Julie A, Pierson, C Renee, Roesgen, Jeff T, Cabrera, Edelberto J, Nelson, Sandra L
Published in Journal of biomolecular screening (01.02.2002)
Published in Journal of biomolecular screening (01.02.2002)
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Journal Article
Differential effects of somatostatin (SRIH) and a SRIH analog, SMS 201-995, on the secretion of growth hormone and thyroid-stimulating hormone in man
Williams, T C, Kelijman, M, Crelin, W C, Downs, T R, Frohman, L A
Published in The journal of clinical endocrinology and metabolism (01.01.1988)
Published in The journal of clinical endocrinology and metabolism (01.01.1988)
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Journal Article
Effects of β3-Adrenergic Receptor Activation on Rat Urinary Bladder Hyperactivity Induced by Ovariectomy
F. Aura Kullmann, Brian J. Limberg, Debra E. Artim, Mansi Shah, Thomas R. Downs, Dan Contract, John Wos, Jan S. Rosenbaum, William C. de Groat
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
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Journal Article
Effects of β 3 -Adrenergic Receptor Activation on Rat Urinary Bladder Hyperactivity Induced by Ovariectomy
Kullmann, F. Aura, Limberg, Brian J., Artim, Debra E., Shah, Mansi, Downs, Thomas R., Contract, Dan, Wos, John, Rosenbaum, Jan S., de Groat, William C.
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
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