A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins
Ryan, Anthony, Lynch, Mark, Smith, Sinead M, Amu, Sylvie, Nel, Hendrik J, McCoy, Claire E, Dowling, Jennifer K, Draper, Eve, O'Reilly, Vincent, McCarthy, Ciara, O'Brien, Julie, Ní Eidhin, Déirdre, O'Connell, Mary J, Keogh, Brian, Morton, Charles O, Rogers, Thomas R, Fallon, Padraic G, O'Neill, Luke A, Kelleher, Dermot, Loscher, Christine E
Published in PLoS pathogens (01.06.2011)
Published in PLoS pathogens (01.06.2011)
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Biomaterial and Therapeutic Approaches for the Manipulation of Macrophage Phenotype in Peripheral and Central Nerve Repair
Dervan, Adrian, Franchi, Antonio, Almeida-Gonzalez, Francisco R, Dowling, Jennifer K, Kwakyi, Ohemaa B, McCoy, Claire E, O'Brien, Fergal J, Hibbitts, Alan
Published in Pharmaceutics (15.12.2021)
Published in Pharmaceutics (15.12.2021)
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Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype
De Santi, Chiara, Nally, Frances K., Afzal, Remsha, Duffy, Conor P., Fitzsimons, Stephen, Annett, Stephanie L., Robson, Tracy, Dowling, Jennifer K., Cryan, Sally-Ann, McCoy, Claire E.
Published in Molecular therapy. Nucleic acids (13.09.2022)
Published in Molecular therapy. Nucleic acids (13.09.2022)
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Journal Article
Inhibition of pro-inflammatory signaling in human primary macrophages by enhancing arginase-2 via target site blockers
Fitzsimons, Stephen, Muñoz-San Martín, María, Nally, Frances, Dillon, Eugene, Fashina, Ifeolutembi A., Strowitzki, Moritz J., Ramió-Torrentà, Lluís, Dowling, Jennifer K., De Santi, Chiara, McCoy, Claire E.
Published in Molecular therapy. Nucleic acids (12.09.2023)
Published in Molecular therapy. Nucleic acids (12.09.2023)
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Journal Article
Parsing the IL-37-Mediated Suppression of Inflammasome Function
Rudloff, Ina, Ung, Holly K, Dowling, Jennifer K, Mansell, Ashley, D'Andrea, Laura, Ellisdon, Andrew M, Whisstock, James C, Berger, Philip J, Nold-Petry, Claudia A, Nold, Marcel F
Published in Cells (Basel, Switzerland) (10.01.2020)
Published in Cells (Basel, Switzerland) (10.01.2020)
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Journal Article
Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanisms
Court, Nathalie, Rose, Stéphanie, Bourigault, Marie-Laure, Front, Sophie, Martin, Olivier R, Dowling, Jennifer K, Kenny, Elaine F, O'Neill, Luke, Erard, François, Quesniaux, Valerie F J
Published in PloS one (16.09.2011)
Published in PloS one (16.09.2011)
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Journal Article
Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition
Tate, Michelle D., Ong, James D. H., Dowling, Jennifer K., McAuley, Julie L., Robertson, Avril B., Latz, Eicke, Drummond, Grant R., Cooper, Matthew A., Hertzog, Paul J., Mansell, Ashley
Published in Scientific reports (10.06.2016)
Published in Scientific reports (10.06.2016)
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Journal Article
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
Dowling, Jennifer K., Afzal, Remsha, Gearing, Linden J., Cervantes-Silva, Mariana P., Annett, Stephanie, Davis, Gavin M., De Santi, Chiara, Assmann, Nadine, Dettmer, Katja, Gough, Daniel J., Bantug, Glenn R., Hamid, Fidinny I., Nally, Frances K., Duffy, Conor P., Gorman, Aoife L., Liddicoat, Alex M., Lavelle, Ed C., Hess, Christoph, Oefner, Peter J., Finlay, David K., Davey, Gavin P., Robson, Tracy, Curtis, Annie M., Hertzog, Paul J., Williams, Bryan R. G., McCoy, Claire E.
Published in Nature communications (05.03.2021)
Published in Nature communications (05.03.2021)
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Journal Article
PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome
Pinar, Anita, Dowling, Jennifer K., Bitto, Natalie J., Robertson, Avril A.B., Latz, Eicke, Stewart, Cameron R., Drummond, Grant R., Cooper, Matthew A., McAuley, Julie L., Tate, Michelle D., Mansell, Ashley
Published in The Journal of biological chemistry (20.01.2017)
Published in The Journal of biological chemistry (20.01.2017)
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Journal Article
Biochemical regulation of the inflammasome
Dowling, Jennifer K., O'Neill, Luke A. J.
Published in Critical reviews in biochemistry and molecular biology (01.09.2012)
Published in Critical reviews in biochemistry and molecular biology (01.09.2012)
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Journal Article
Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase‐5 in human monocytes
Bitto, Natalie J, Baker, Paul J, Dowling, Jennifer K, Wray‐McCann, Georgie, De Paoli, Amanda, Tran, Le Son, Leung, Pak Ling, Stacey, Katryn J, Mansell, Ashley, Masters, Seth L, Ferrero, Richard L
Published in Immunology and cell biology (01.11.2018)
Published in Immunology and cell biology (01.11.2018)
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Journal Article
Multi-factorial nerve guidance conduit engineering improves outcomes in inflammation, angiogenesis and large defect nerve repair
Hibbitts, Alan J., Kočí, Zuzana, Kneafsey, Simone, Matsiko, Amos, Žilić, Leyla, Dervan, Adrian, Hinton, Paige, Chen, Gang, Cavanagh, Brenton, Dowling, Jennifer K., McCoy, Claire E., Buckley, Conor T., Archibald, Simon J., O'Brien, Fergal J.
Published in Matrix biology (01.02.2022)
Published in Matrix biology (01.02.2022)
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Journal Article
Impact of Exercise on Immunometabolism in Multiple Sclerosis
Afzal, Remsha, Dowling, Jennifer K, McCoy, Claire E
Published in Journal of clinical medicine (21.09.2020)
Published in Journal of clinical medicine (21.09.2020)
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Journal Article
Novel mineralocorticoid receptor mechanisms regulate cardiac tissue inflammation in male mice
Ong, Gregory S Y, Cole, Timothy J, Tesch, Gregory H, Morgan, James, Dowling, Jennifer K, Mansell, Ashley, Fuller, Peter J, Young, Morag J
Published in Journal of endocrinology (01.08.2020)
Published in Journal of endocrinology (01.08.2020)
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Journal Article
The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses
Dowling, Jennifer K, Tate, Michelle D, Rosli, Sarah, Bourke, Nollaig M, Bitto, Natalie, Lauterbach, Mario A, Cheung, Shane, Ve, Thomas, Kobe, Bostjan, Golenbock, Douglas, Mansell, Ashley
Published in The Journal of immunology (1950) (15.04.2019)
Published in The Journal of immunology (1950) (15.04.2019)
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Neurological disorders after severe pneumonia are associated with translocation of endogenous bacteria from the lung to the brain
Ma, Qingle, Yao, Chenlu, Wu, Yi, Wang, Heng, Fan, Qin, Yang, Qianyu, Xu, Jialu, Dai, Huaxing, Zhang, Yue, Xu, Fang, Lu, Ting, Dowling, Jennifer K, Wang, Chao
Published in Science advances (20.10.2023)
Published in Science advances (20.10.2023)
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Journal Article
Promyelocytic Leukemia Protein Interacts with the Apoptosis-associated Speck-like Protein to Limit Inflammasome Activation
Dowling, Jennifer K., Becker, Christine E., Bourke, Nollaig M., Corr, Sinead C., Connolly, Dympna J., Quinn, Susan R., Pandolfi, Paolo P., Mansell, Ashley, O'Neill, Luke A.J.
Published in The Journal of biological chemistry (07.03.2014)
Published in The Journal of biological chemistry (07.03.2014)
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