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Published in ACS medicinal chemistry letters (11.05.2017)
Published in ACS medicinal chemistry letters (11.05.2017)
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Potent, Selective and Orally Bioavailable Dihydropyrimidine Inhibitors of Rho Kinase (ROCK1) as Potential Therapeutic Agents for Cardiovascular Diseases
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Published in Journal of medicinal chemistry (13.11.2008)
Published in Journal of medicinal chemistry (13.11.2008)
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Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors
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Published in Journal of medicinal chemistry (11.01.2007)
Published in Journal of medicinal chemistry (11.01.2007)
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Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors
Goodman, Krista B., Bury, Michael J., Cheung, Mui, Cichy-Knight, Maria A., Dowdell, Sarah E., Dunn, Allison K., Lee, Dennis, Lieby, Jeffrey A., Moore, Michael L., Scherzer, Daryl A., Sha, Deyou, Suarez, Dominic P., Murphy, Dennis J., Harpel, Mark R., Manas, Eric S., McNulty, Dean E., Annan, Roland S., Matico, Rosalie E., Schwartz, Benjamin K., Trill, John J., Sweitzer, Thomas D., Wang, Da-yuan, Keller, Paul M., Krawiec, John A., Jaye, Michael C.
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Discovery of Aminofurazan-azabenzimidazoles as Inhibitors of Rho-Kinase with High Kinase Selectivity and Antihypertensive Activity
Stavenger, Robert A, Cui, Haifeng, Dowdell, Sarah E, Franz, Robert G, Gaitanopoulos, Dimitri E, Goodman, Krista B, Hilfiker, Mark A, Ivy, Robert L, Leber, Jack D, Marino, Joseph P, Oh, Hye-Ja, Viet, Andrew Q, Xu, Weiwei, Ye, Guosen, Zhang, Daohua, Zhao, Yongdong, Jolivette, Larry J, Head, Martha S, Semus, Simon F, Elkins, Patricia A, Kirkpatrick, Robert B, Dul, Edward, Khandekar, Sanjay S, Yi, Tracey, Jung, David K, Wright, Lois L, Smith, Gary K, Behm, David J, Doe, Christopher P, Bentley, Ross, Chen, Zunxuan X, Hu, Erding, Lee, Dennis
Published in Journal of medicinal chemistry (11.01.2007)
Published in Journal of medicinal chemistry (11.01.2007)
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CCR2 receptor antagonists: Optimization of biaryl sulfonamides to increase activity in whole blood
Wang, Gren Z., Haile, Pamela A., Daniel, Tom, Belot, Benjamin, Viet, Andrew Q., Goodman, Krista B., Sha, Deyou, Dowdell, Sarah E., Varga, Norbert, Hong, Xuan, Chakravorty, Subhas, Webb, Christine, Cornejo, Carla, Olzinski, Alan, Bernard, Roberta, Evans, Christopher, Emmons, Amanda, Briand, Jacques, Chung, Chun-Wa, Quek, Ruben, Lee, Dennis, Gough, Peter J., Sehon, Clark A.
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Aminomethylpiperazines as selective urotensin antagonists
Hilfiker, Mark A., Zhang, Daohua, Dowdell, Sarah E., Goodman, Krista B., McAtee, John J., Dodson, Jason W., Viet, Andrew Q., Wang, Gren Z., Sehon, Clark A., Behm, David J., Wu, Zining, Carballo, Luz H., Douglas, Stephen A., Neeb, Michael J.
Published in Bioorganic & medicinal chemistry (15.08.2008)
Published in Bioorganic & medicinal chemistry (15.08.2008)
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Development of potent and selective small-molecule human Urotensin-II antagonists
McAtee, John J., Dodson, Jason W., Dowdell, Sarah E., Girard, Gerald R., Goodman, Krista B., Hilfiker, Mark A., Sehon, Clark A., Sha, Deyou, Wang, Gren Z., Wang, Ning, Viet, Andrew Q., Zhang, Daohua, Aiyar, Nambi V., Behm, David J., Carballo, Luz H., Evans, Christopher A., Fries, Harvey E., Nagilla, Rakesh, Roethke, Theresa J., Xu, Xiaoping, Yuan, Catherine C.K., Douglas, Stephen A., Neeb, Michael J.
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Potent and selective small-molecule human urotensin-II antagonists with improved pharmacokinetic profiles
McAtee, John J., Dodson, Jason W., Dowdell, Sarah E., Erhard, Karl, Girard, Gerald R., Goodman, Krista B., Hilfiker, Mark A., Jin, Jian, Sehon, Clark A., Sha, Deyou, Shi, Dongchuan, Wang, Feng, Wang, Gren Z., Wang, Ning, Wang, Yonghui, Viet, Andrew Q., Yuan, Catherine C.K., Zhang, Daohua, Aiyar, Nambi V., Behm, David J., Carballo, Luz H., Evans, Christopher A., Fries, Harvey E., Nagilla, Rakesh, Roethke, Theresa J., Xu, Xiaoping, Douglas, Stephen A., Neeb, Michael J.
Published in Bioorganic & medicinal chemistry letters (01.07.2008)
Published in Bioorganic & medicinal chemistry letters (01.07.2008)
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Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1
Kallander, Lara S., Washburn, David, Hilfiker, Mark A., Eidam, Hilary Schenck, Lawhorn, Brian G., Prendergast, Joanne, Fox, Ryan, Dowdell, Sarah, Manns, Sharada, Hoang, Tram, Zhao, Steve, Ye, Guosen, Hammond, Marlys, Holt, Dennis A., Roethke, Theresa, Hong, Xuan, Reid, Robert A., Gampe, Robert, Zhang, Hong, Diaz, Elsie, Rendina, Alan R., Quinn, Amy M., Willette, Bob
Published in ACS medicinal chemistry letters (12.07.2018)
Published in ACS medicinal chemistry letters (12.07.2018)
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Year of Publication 12.09.2016
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Mutant-Selective Thyromimetics for the Chemical Rescue of Thyroid Hormone Receptor Mutants Associated with Resistance to Thyroid Hormone
Shi, Youheng, Ye, Haifen, Link, Kristian H, Putnam, Marc C, Hubner, Isaac, Dowdell, Sarah, Koh, John T
Published in Biochemistry (Easton) (29.03.2005)
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Photo-caged agonists of the nuclear receptors RARγ and TRβ provide unique time-dependent gene expression profiles for light-activated gene patterning
Link, Kristian H., Cruz, Federico G., Ye, Hai-Fen, O’Reilly, Kathryn E., Dowdell, Sarah, Koh, John T.
Published in Bioorganic & medicinal chemistry (15.11.2004)
Published in Bioorganic & medicinal chemistry (15.11.2004)
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Photo-caged agonists of the nuclear receptors RARgamma and TRbeta provide unique time-dependent gene expression profiles for light-activated gene patterning
Link, Kristian H, Cruz, Federico G, Ye, Hai-Fen, O'reilly, Kathryn E, Dowdell, Sarah, Koh, John T
Published in Bioorganic & medicinal chemistry (15.11.2004)
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Year of Publication 20.12.2018
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Year of Publication 16.05.2018
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N-HYDROXYFORMAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THEM FOR USE AS BMP1, TLL1 AND/OR TLL2 INHIBITORS
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