Proteomic analysis of palmitoylated platelet proteins
Dowal, Louisa, Yang, Wei, Freeman, Michael R., Steen, Hanno, Flaumenhaft, Robert
Published in Blood (29.09.2011)
Published in Blood (29.09.2011)
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Journal Article
Protein kinase C phosphorylation of PLCβ1 regulates its cellular localization
Aisiku, Omozuanvbo, Dowal, Louisa, Scarlata, Suzanne
Published in Archives of biochemistry and biophysics (15.05.2011)
Published in Archives of biochemistry and biophysics (15.05.2011)
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Journal Article
Intrinsic Properties of Brown and White Adipocytes Have Differential Effects on Macrophage Inflammatory Responses
Guntur, Kalyani, Gesta, Stephane, Vishnudas, Vivek K., Narain, Niven R., Sarangarajan, Rangaprasad, Mogre, Saie, Shah, Chahan, Ranjan, Jyoti, Majumdar, Ishita Deb, Akella, Syamala, Phat, Sarah, Parameswaran, Pooja, Dowal, Louisa, Thapa, Khampaseuth
Published in Mediators of inflammation (01.01.2017)
Published in Mediators of inflammation (01.01.2017)
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Journal Article
Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1
Dowal, Louisa, Sim, Derek S, Dilks, James R, Blair, Price, Beaudry, Sarah, Denker, Bradley M, Koukos, Georgios, Kuliopulos, Athan, Flaumenhaft, Robert
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2011)
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Journal Article
N-terminal Myristoylation Regulates Calcium-induced Conformational Changes in Neuronal Calcium Sensor-1
Jeromin, Andreas, Muralidhar, Dasari, Parameswaran, Malavika Nair, Roder, John, Fairwell, Thomas, Scarlata, Suzanne, Dowal, Louisa, Mustafi, Sourajit M., Chary, Kandala V.R., Sharma, Yogendra
Published in The Journal of biological chemistry (25.06.2004)
Published in The Journal of biological chemistry (25.06.2004)
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Journal Article
Selective interaction of the C2 domains of phospholipase C-β1 and -β2 with activated Gαq subunits: An alternative function for C2-signaling modules
Wang, Tieli, Pentyala, Srinivas, Elliott, John T., Dowal, Louisa, Gupta, Ekta, Rebecchi, Mario J., Scarlata, Suzanne
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.1999)
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Journal Article
Stable Association between Gαq and Phospholipase Cβ1 in Living Cells
Dowal, Louisa, Provitera, Paxton, Scarlata, Suzanne
Published in The Journal of biological chemistry (18.08.2006)
Published in The Journal of biological chemistry (18.08.2006)
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Journal Article
Abstract 703: The anti-cancer drug BPM 31510 elicits immune-modulatory effects through regulation of IL-10
Dowal, Louisa, Nastke, Maria D., Gaur, Nidhi, Singh, Richa, Fowler, Samantha, Jayashankar, Shyamali, Diers, Anne R., Gesta, Stephane, Vishnudas, Vivek, Narain, Niven R., Sarangarajan, Rangaprasad
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract LB-223: ATLASTMreveals a dominant inhibitory antigen in melanoma patients, and a reduced breadth of tumor-associated antigen-specific T cells in non-responders to checkpoint blockade
Dowal, Louisa, Lyubetskaya, Anna, Cabral, Crystal, Croll, Mariya, Warren, Christopher, Perry, James, Hayes, Melissa, Loizeaux, James, Foti, James, Flechtner, Jessica B., Dobson, Jason R., Hodi, F. Stephen, Broom, Wendy
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
A phase 1/2a study of GEN-009, a neoantigen vaccine based on autologous peptide immune responses
Cohen, Roger B., Johnson, Melissa Lynne, Twardowski, Przemyslaw, Stein, Mark N., Vaishampayan, Ulka N., Dobson, Jason R., Foti, James, Agnihotri, Parul, Dowal, Louisa, Broom, Wendy, McNeil, Lisa, Davis, Thomas A., Flechtner, Jessica
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
Abstract 1680: BPM31510, an anti-cancer agent selectively causes activation and proliferation of T cells, demonstrating potential utility in an immune-oncology setting
Nastke, Maria-D, Gaur, Nidhi, Dowal, Louisa, Fowler, Samantha, Diers, Anne, Gesta, Stephane, Vishnudas, Vivek K., Narain, Niven R., Sarangarajan, Rangaprasad
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
The Platelet Actin Cytoskeleton Associates with SNAREs and Participates in α-Granule Secretion
Woronowicz, Kamil, Dilks, James R, Rozenvayn, Nataliya, Dowal, Louisa, Blair, Price S, Peters, Christian G, Woronowicz, Lucyna, Flaumenhaft, Robert
Published in Biochemistry (Easton) (01.06.2010)
Published in Biochemistry (Easton) (01.06.2010)
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Journal Article
Abstract 2745: The PLANET manufacturing process reproducibly generates high-quality neoantigen-targeted peripheral T cells (NPTs) for adoptive T cell therapy in the TiTAN clinical trial
Zope, Harshal, Nande, Rounak, Jain, Manish, Hubbard, Charley, Dowal, Louisa, Foti, James, Loizeaux, James, Cabral, Crystal, DeOliveira, Daniel B., Yang, Guohan, Reuter, Mercay, Flechtner, Jessica Baker, Stapleton, Raymond
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract CT153: TiTAN: a phase 1 study of GEN-011, a neoantigen-targeted peripheral blood-derived T cell therapy with broad neoantigen targeting
Gillison, Maura, Niu, Jiaxin, Olson, Daniel, Stein, Mark, Aggen, David, Acharya, Utkarsh, Creelan, Benjamin, Hernandez, Richard, Price, Jessica, Mancini, Kevin J., Dowal, Louisa, Foti, James, Vemulapalli, Vijetha, Shainheit, Mara, Golshadi, Masoud, Stapleton, Raymond D., Flechtner, Jessica B., Davis, Thomas A.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
526 InhibigenTM-specific responses suppress anti-tumor immunity and promote tumor growth
DeVault, Victoria, Dadali, Tulin, Starobinets, Hanna, Lema, Kevin, Rinaldi, Stephanie, Odeh, Osaruese, Arnold, Julie, Sheehan, Dylan, Nguyen, Cindy, Dowal, Louisa, Flechtner, Jessica, Visintin, Alberto, Lam, Hubert
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Acyl-Protein Thioesterase 1 Functions in Palmitoylation/Depalmitoylation Cycles of G Proteins and Regulates Platelet Activation
Dowal, Louisa M., Dilks, James R., Fadel, Nathalie A., Aisiku, Omozuanvbo R., Merrill-Skoloff, Glenn, Flaumenhaft, Robert C.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor
Dockendorff, Chris, Aisiku, Omozuanvbo, VerPlank, Lynn, Dilks, James R, Smith, Daniel A, Gunnink, Susanna F, Dowal, Louisa, Negri, Joseph, Palmer, Michelle, MacPherson, Lawrence, Schreiber, Stuart L, Flaumenhaft, Robert
Published in ACS medicinal chemistry letters (08.03.2012)
Published in ACS medicinal chemistry letters (08.03.2012)
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Journal Article
An Allosteric Modulator of PAR1 Demonstrates Selective Inhibition of G Protein Coupling and Impairs Thrombus Formation In Vivo
Aisiku, Omozuanvbo R, Dockendorff, Chris, Gunnick, Suzanne F, Smith, Daniel A., Dilks, James R., Dowal, Louisa M., Flaumenhaft, Robert C.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article