Inflammasome-targeted therapy might prevent adverse perinatal outcomes of recurrent chronic intervillositis of unknown etiology
Mattuizzi, Aurélien, Sauvestre, Fanny, Fargeix, Tiphaine, White, Eoghann, Leibler, Claire, Cargou, Marine, Dugot-Senant, Nathalie, Douchet, Isabelle, Duluc, Dorothée, Bordes, Cécile, Truchetet, Marie-Élise, Richez, Christophe, Forcade, Édouard, Duffau, Pierre, Viallard, Jean-François, Sentilhes, Loïc, Blanco, Patrick, Lazaro, Estibaliz
Published in Nature communications (30.10.2024)
Published in Nature communications (30.10.2024)
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Platelets Induce Thymic Stromal Lymphopoietin Production by Endothelial Cells: Contribution to Fibrosis in Human Systemic Sclerosis
Truchetet, Marie‐Elise, Demoures, Béatrice, Eduardo Guimaraes, Jorge, Bertrand, Anne, Laurent, Paôline, Jolivel, Valérie, Douchet, Isabelle, Jacquemin, Clément, Khoryati, Liliane, Duffau, Pierre, Lazaro, Estibaliz, Richez, Christophe, Seneschal, Julien, Doutre, Marie‐Sylvie, Pellegrin, Jean‐Luc, Constans, Joël, Schaeverbeke, Thierry, Blanco, Patrick, Contin‐Bordes, Cécile
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2016)
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OX40L/OX40 axis impairs follicular and natural Treg function in human SLE
Jacquemin, Clément, Augusto, Jean-François, Scherlinger, Marc, Gensous, Noémie, Forcade, Edouard, Douchet, Isabelle, Levionnois, Emeline, Richez, Christophe, Lazaro, Estibaliz, Duffau, Pierre, Truchetet, Marie-Elise, Seneschal, Julien, Couzi, Lionel, Pellegrin, Jean-Luc, Viallard, Jean-François, Schaeverbeke, Thierry, Pascual, Virginia, Contin-Bordes, Cécile, Blanco, Patrick
Published in JCI insight (20.12.2018)
Published in JCI insight (20.12.2018)
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Septic shock sera containing circulating histones induce dendritic cell-regulated necrosis in fatal septic shock patients
Raffray, Loic, Douchet, Isabelle, Augusto, Jean-Francois, Youssef, Jihad, Contin-Bordes, Cecile, Richez, Christophe, Duffau, Pierre, Truchetet, Marie-Elise, Moreau, Jean-Francois, Cazanave, Charles, Leroux, Lionel, Mourrissoux, Gaelle, Camou, Fabrice, Clouzeau, Benjamin, Jeannin, Pascale, Delneste, Yves, Gabinski, Claude, Guisset, Olivier, Lazaro, Estibaliz, Blanco, Patrick
Published in Critical care medicine (01.04.2015)
Published in Critical care medicine (01.04.2015)
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Biochemical properties and three-dimensional structures of two extracellular lipolytic enzymes from Bacillus subtilis
Eggert, Thorsten, van Pouderoyen, Gertie, Pencreac'h, Gaëlle, Douchet, Isabelle, Verger, Robert, Dijkstra, Bauke W., Jaeger, Karl-Erich
Published in Colloids and surfaces, B, Biointerfaces (01.09.2002)
Published in Colloids and surfaces, B, Biointerfaces (01.09.2002)
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Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states
Furman, David, Chang, Junlei, Lartigue, Lydia, Bolen, Christopher R, Haddad, François, Gaudilliere, Brice, Ganio, Edward A, Fragiadakis, Gabriela K, Spitzer, Matthew H, Douchet, Isabelle, Daburon, Sophie, Moreau, Jean-François, Nolan, Garry P, Blanco, Patrick, Déchanet-Merville, Julie, Dekker, Cornelia L, Jojic, Vladimir, Kuo, Calvin J, Davis, Mark M, Faustin, Benjamin
Published in Nature Medicine (01.02.2017)
Published in Nature Medicine (01.02.2017)
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Magazine Article
OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response
Jacquemin, Clément, Schmitt, Nathalie, Contin-Bordes, Cécile, Liu, Yang, Narayanan, Priya, Seneschal, Julien, Maurouard, Typhanie, Dougall, David, Davizon, Emily Spence, Dumortier, Hélène, Douchet, Isabelle, Raffray, Loïc, Richez, Christophe, Lazaro, Estibaliz, Duffau, Pierre, Truchetet, Marie-Elise, Khoryati, Liliane, Mercié, Patrick, Couzi, Lionel, Merville, Pierre, Schaeverbeke, Thierry, Viallard, Jean-François, Pellegrin, Jean-Luc, Moreau, Jean-François, Muller, Sylviane, Zurawski, Sandy, Coffman, Robert L., Pascual, Virginia, Ueno, Hideki, Blanco, Patrick
Published in Immunity (Cambridge, Mass.) (16.06.2015)
Published in Immunity (Cambridge, Mass.) (16.06.2015)
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Clusterin Neutralizes the Inflammatory and Cytotoxic Properties of Extracellular Histones in Sepsis
Augusto, Jean-François, Beauvillain, Céline, Poli, Caroline, Paolini, Léa, Tournier, Isabelle, Pignon, Pascale, Blanchard, Simon, Preisser, Laurence, Soleti, Raffaella, Delépine, Chloé, Monnier, Marine, Douchet, Isabelle, Asfar, Pierre, Beloncle, François, Guisset, Olivier, Prével, Renaud, Mercat, Alain, Vinatier, Emeline, Goret, Julien, Subra, Jean-François, Couez, Dominique, Wilson, Mark R, Blanco, Patrick, Jeannin, Pascale, Delneste, Yves
Published in American journal of respiratory and critical care medicine (15.07.2023)
Published in American journal of respiratory and critical care medicine (15.07.2023)
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Interleukin‐1β–Activated Microvascular Endothelial Cells Promote DC‐SIGN–Positive Alternatively Activated Macrophages as a Mechanism of Skin Fibrosis in Systemic Sclerosis
Laurent, Paôline, Lapoirie, Joelle, Leleu, Damien, Levionnois, Emeline, Grenier, Cyrielle, Jurado‐Mestre, Blanca, Lazaro, Estibaliz, Duffau, Pierre, Richez, Christophe, Seneschal, Julien, Pellegrin, Jean‐Luc, Constans, Joel, Schaeverbeke, Thierry, Douchet, Isabelle, Duluc, Dorothée, Pradeu, Thomas, Chizzolini, Carlo, Blanco, Patrick, Truchetet, Marie‐Elise, Contin‐Bordes, Cécile
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2022)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2022)
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Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus
Duffau, Pierre, Seneschal, Julien, Nicco, Carole, Richez, Christophe, Lazaro, Estibaliz, Douchet, Isabelle, Bordes, Cécile, Viallard, Jean-François, Goulvestre, Claire, Pellegrin, Jean-Luc, Weil, Bernard, Moreau, Jean-François, Batteux, Frédéric, Blanco, Patrick
Published in Science translational medicine (01.09.2010)
Published in Science translational medicine (01.09.2010)
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Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation
Poissonnier, Amanda, Guégan, Jean-Philippe, Nguyen, Ha Thanh, Best, Daniel, Levoin, Nicolas, Kozlov, Guennadi, Gehring, Kalle, Pineau, Raphael, Jouan, Florence, Morere, Lucie, Martin, Sophie, Thomas, Mélissa, Lazaro, Estibaliz, Douchet, Isabelle, Ducret, Thomas, van de Weghe, Pierre, Blanco, Patrick, Jean, Mickael, Vacher, Pierre, Legembre, Patrick
Published in Nature chemical biology (01.12.2018)
Published in Nature chemical biology (01.12.2018)
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Disrupting the CD95-PLC gamma 1 interaction prevents Th17-driven inflammation
Poissonnier, Amanda, Guegan, Jean-Philippe, Nguyen, Ha Thanh, Best, Daniel, Levoin, Nicolas, Kozlov, Guennadi, Gehring, Kalle, Pineau, Raphael, Jouan, Florence, Morere, Lucie, Martin, Sophie, Thomas, Melissa, Lazaro, Estibaliz, Douchet, Isabelle, Ducret, Thomas, van de Weghe, Pierre, Blanco, Patrick, Jean, Mickael, Vacher, Pierre, Legembre, Patrick
Published in Nature chemical biology (01.12.2018)
Published in Nature chemical biology (01.12.2018)
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Journal Article
Neutrophil-derived mitochondrial DNA promotes receptor activator of nuclear factor κB and its ligand signalling in rheumatoid arthritis
Contis, Anne, Mitrovic, Stéphane, Lavie, Julie, Douchet, Isabelle, Lazaro, Estibaliz, Truchetet, Marie-Elise, Goizet, Cyril, Contin-Bordes, Cécile, Schaeverbeke, Thierry, Blanco, Patrick, Rossignol, Rodrigue, Faustin, Benjamin, Richez, Christophe, Duffau, Pierre
Published in Rheumatology (Oxford, England) (01.07.2017)
Published in Rheumatology (Oxford, England) (01.07.2017)
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IgE Inhibits Toll‐like Receptor 7– and Toll‐like Receptor 9–Mediated Expression of Interferon‐α by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus
Khoryati, Liliane, Augusto, Jean‐François, Shipley, Emilie, Contin‐Bordes, Cécile, Douchet, Isabelle, Mitrovic, Stéphane, Truchetet, Marie‐Elise, Lazaro, Estibaliz, Duffau, Pierre, Couzi, Lionel, Jacquemin, Clément, Barnetche, Thomas, Vacher, Pierre, Schaeverbeke, Thierry, Blanco, Patrick, Richez, Christophe
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2016)
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T Follicular Regulatory (TFR) Cell Deficiency during Chronic Graft-Versus-Host Disease Is Improved By Low-Dose IL-2 Therapy
Forcade, Edouard, Kamihara, Yusuke, Kim, Haesook T, Douchet, Isabelle, Koreth, John, Hirakawa, Masahiro, Cutler, Corey, Nikiforow, Sarah, Ho, Vincent T, Armand, Philippe, Alyea, Edwin, Blanco, Patrick, Blazar, Bruce, Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Characterization of an exported monoglyceride lipase from Mycobacterium tuberculosis possibly involved in the metabolism of host cell membrane lipids
Côtes, Karen, Dhouib, Rabeb, Douchet, Isabelle, Chahinian, Henri, de Caro, Alain, Carrière, Frédéric, Canaan, Stéphane
Published in Biochemical journal (15.12.2007)
Published in Biochemical journal (15.12.2007)
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HIV Protease Inhibitors Cure Lupus-Prone Mice and Prevent T Helper 17 Cell-Driven Inflammation By Inhibiting CD95-Non-Apoptotic Signaling Pathway
Charrier, Manon, Poissonnier, Amanda, Best, Daniel, Guégan, Jean-Philippe, Levoin, Nicolas, Pineau, Raphael, Jouan, Florence, Nguyen, Ha Thanh, Morere, Lucie, Martin, Sophie, Thomas, Melissa, Lazaro, Estibaliz, Richez, Christophe, Douchet, Isabelle, Ducret, Thomas, van de Weghe, Pierre, Blanco, Patrick, Jean, Mickael, Vacher, Pierre, Legembre, Patrick
Published in Arthritis & rheumatology (Hoboken, N.J.) (2018)
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Published in Arthritis & rheumatology (Hoboken, N.J.) (2018)
Journal Article
IgE Inhibits Toll-like Receptor 7- and Toll-like Receptor 9-Mediated Expression of Interferon-[alpha] by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus
Khoryati, Liliane, Augusto, Jean-François, Shipley, Emilie, Contin-Bordes, Cécile, Douchet, Isabelle, Mitrovic, Stéphane, Truchetet, Marie-Elise, Lazaro, Estibaliz, Duffau, Pierre, Couzi, Lionel, Jacquemin, Clément, Barnetche, Thomas, Vacher, Pierre, Schaeverbeke, Thierry, Blanco, Patrick, Richez, Christophe
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2016)
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Potential Role of Mycoplasma hominis in Interleukin (IL)-17-Producing CD4⁺ T-Cell Generation Via Induction of IL-23 Secretion by Human Dendritic Cells
Truchetet, Marie-Elise, Beven, Laure, Renaudin, Hélène, Douchet, Isabelle, Férandon, Cyril, Charron, Alain, Blanco, Patrick, Schaeverbeke, Thierry, Contin-Bordes, Cécile, Bébéar, Cécile
Published in The Journal of infectious diseases (01.12.2011)
Published in The Journal of infectious diseases (01.12.2011)
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