Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer
Bai, Longchuan, Zhou, Bing, Yang, Chao-Yie, Ji, Jiao, McEachern, Donna, Przybranowski, Sally, Jiang, Hui, Hu, Jiantao, Xu, Fuming, Zhao, Yujun, Liu, Liu, Fernandez-Salas, Ester, Xu, Jing, Dou, Yali, Wen, Bo, Sun, Duxin, Meagher, Jennifer, Stuckey, Jeanne, Hayes, Daniel F, Li, Shunqiang, Ellis, Matthew J, Wang, Shaomeng
Published in Cancer research (Chicago, Ill.) (01.05.2017)
Published in Cancer research (Chicago, Ill.) (01.05.2017)
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Hepatic HuR modulates lipid homeostasis in response to high-fat diet
Zhang, Zhuojun, Zong, Chen, Jiang, Mingyang, Hu, Han, Cheng, Xiaolei, Ni, Juhua, Yi, Xia, Jiang, Bin, Tian, Feng, Chang, Ming-Wen, Su, Wen, Zhu, Lijun, Li, Jinfan, Xiang, Xueping, Miao, Congxiu, Gorospe, Myriam, de Cabo, Rafael, Dou, Yali, Ju, Zhenyu, Yang, Jichun, Jiang, Changtao, Yang, Zhongzhou, Wang, Wengong
Published in Nature communications (16.06.2020)
Published in Nature communications (16.06.2020)
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Cryo-EM structure of the human MLL1 core complex bound to the nucleosome
Park, Sang Ho, Ayoub, Alex, Lee, Young-Tae, Xu, Jing, Kim, Hanseong, Zheng, Wei, Zhang, Biao, Sha, Liang, An, Sojin, Zhang, Yang, Cianfrocco, Michael A., Su, Min, Dou, Yali, Cho, Uhn-Soo
Published in Nature communications (05.12.2019)
Published in Nature communications (05.12.2019)
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Structural basis for activity regulation of MLL family methyltransferases
Li, Yanjing, Han, Jianming, Zhang, Yuebin, Cao, Fang, Liu, Zhijun, Li, Shuai, Wu, Jian, Hu, Chunyi, Wang, Yan, Shuai, Jin, Chen, Juan, Cao, Liaoran, Li, Dangsheng, Shi, Pan, Tian, Changlin, Zhang, Jian, Dou, Yali, Li, Guohui, Chen, Yong, Lei, Ming
Published in Nature (London) (25.02.2016)
Published in Nature (London) (25.02.2016)
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Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin
Lee, Young-Tae, Ayoub, Alex, Park, Sang-Ho, Sha, Liang, Xu, Jing, Mao, Fengbiao, Zheng, Wei, Zhang, Yang, Cho, Uhn-Soo, Dou, Yali
Published in Nature communications (19.05.2021)
Published in Nature communications (19.05.2021)
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High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction
Karatas, Hacer, Townsend, Elizabeth C, Cao, Fang, Chen, Yong, Bernard, Denzil, Liu, Liu, Lei, Ming, Dou, Yali, Wang, Shaomeng
Published in Journal of the American Chemical Society (16.01.2013)
Published in Journal of the American Chemical Society (16.01.2013)
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The Histone Acetyltransferase MOF Is a Key Regulator of the Embryonic Stem Cell Core Transcriptional Network
Li, Xiangzhi, Li, Li, Pandey, Ruchi, Byun, Jung S., Gardner, Kevin, Qin, Zhaohui, Dou, Yali
Published in Cell stem cell (03.08.2012)
Published in Cell stem cell (03.08.2012)
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ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity
Liu, Lu, Inoki, Ayaka, Fan, Kelly, Mao, Fengbiao, Shi, Guojun, Jin, Xi, Zhao, Meiling, Ney, Gina, Jones, Morgan, Sun, Shengyi, Dou, Yali, Inoki, Ken, Qi, Ling, Li, Qing
Published in Blood (24.12.2020)
Published in Blood (24.12.2020)
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Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia
Cao, Fang, Townsend, Elizabeth C., Karatas, Hacer, Xu, Jing, Li, Li, Lee, Shirley, Liu, Liu, Chen, Yong, Ouillette, Peter, Zhu, Jidong, Hess, Jay L., Atadja, Peter, Lei, Ming, Qin, Zhaohui S., Malek, Sami, Wang, Shaomeng, Dou, Yali
Published in Molecular cell (23.01.2014)
Published in Molecular cell (23.01.2014)
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HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis
Sun, Yuqing, Zhou, Bo, Mao, Fengbiao, Xu, Jing, Miao, Hongzhi, Zou, Zhenhua, Phuc Khoa, Le Tran, Jang, Younghoon, Cai, Sheng, Witkin, Matthew, Koche, Richard, Ge, Kai, Dressler, Gregory R., Levine, Ross L., Armstrong, Scott A., Dou, Yali, Hess, Jay L.
Published in Cancer cell (08.10.2018)
Published in Cancer cell (08.10.2018)
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Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Su, Xiaonan, Zhu, Guixin, Ding, Xiaozhe, Lee, Shirley Y, Dou, Yali, Zhu, Bing, Wu, Wei, Li, Haitao
Published in Genes & development (15.03.2014)
Published in Genes & development (15.03.2014)
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Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity
Rogawski, David S., Deng, Jing, Li, Hao, Miao, Hongzhi, Borkin, Dmitry, Purohit, Trupta, Song, Jiho, Chase, Jennifer, Li, Shuangjiang, Ndoj, Juliano, Klossowski, Szymon, Kim, EunGi, Mao, Fengbiao, Zhou, Bo, Ropa, James, Krotoska, Marta Z., Jin, Zhuang, Ernst, Patricia, Feng, Xiaomin, Huang, Gang, Nishioka, Kenichi, Kelly, Samantha, He, Miao, Wen, Bo, Sun, Duxin, Muntean, Andrew, Dou, Yali, Maillard, Ivan, Cierpicki, Tomasz, Grembecka, Jolanta
Published in Nature communications (14.05.2021)
Published in Nature communications (14.05.2021)
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Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF
Zhang, Yi, Jang, Younghoon, Lee, Ji-Eun, Ahn, JaeWoo, Xu, Longxia, Holden, Michael R., Cornett, Evan M., Krajewski, Krzysztof, Klein, Brianna J., Wang, Shu-Ping, Dou, Yali, Roeder, Robert G., Strahl, Brian D., Rothbart, Scott B., Shi, Xiaobing, Ge, Kai, Kutateladze, Tatiana G.
Published in Nature communications (24.05.2019)
Published in Nature communications (24.05.2019)
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H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction
Healton, Sean E., Pinto, Hugo D., Mishra, Laxmi N., Hamilton, Gregory A., Wheat, Justin C., Swist-Rosowska, Kalina, Shukeir, Nicholas, Dou, Yali, Steidl, Ulrich, Jenuwein, Thomas, Gamble, Matthew J., Skoultchi, Arthur I.
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
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