Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design
Hughes, Norman E., Bleisch, Thomas J., Jones, Scott A., Richardson, Timothy I., Doti, Robert A., Wang, Yong, Stout, Stephanie L., Durst, Gregory L., Chambers, Mark G., Oskins, Jennifer L., Lin, Chaohua, Adams, Lisa A., Page, Todd J., Barr, Robert J., Zink, Richard W., Osborne, Harold, Montrose-Rafizadeh, Chahrzad, Norman, Bryan H.
Published in Bioorganic & medicinal chemistry letters (15.07.2016)
Published in Bioorganic & medicinal chemistry letters (15.07.2016)
Get full text
Journal Article
Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists
Burkholder, Timothy P., Cunningham, Brian E., Clayton, Joshua R., Lander, Peter A., Brown, Matthew L., Doti, Robert A., Durst, Gregory L., Montrose-Rafizadeh, Chahrzad, King, Constance, Osborne, Harold E., Amos, Robert M., Zink, Richard W., Stramm, Lawrence E., Burris, Thomas P., Cardona, Guemalli, Konkol, Debra L., Reidy, Charles, Christe, Michael E., Genin, Michael J.
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Get full text
Journal Article
3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists
Neel, David A., Brown, Matthew L., Lander, Peter A., Grese, Timothy A., Defauw, Jean M., Doti, Robert A., Fields, Todd, Kelley, Sally Ann, Smith, Stephon, Zimmerman, Karen M., Steinberg, Mitchell I., Jadhav, Prabhakar K.
Published in Bioorganic & medicinal chemistry letters (16.05.2005)
Published in Bioorganic & medicinal chemistry letters (16.05.2005)
Get full text
Journal Article
Simultaneous determination of enantiomeric purity and erythro/ threo relationship in chiral 1,2-aminoalcohols by NMR using ( R)-(+)- t-butylphenylphosphinothioic acid
Gunderson, Karl G, Shapiro, Michael J, Doti, Robert A, Skiles, Jerry W
Published in Tetrahedron: asymmetry (27.08.1999)
Published in Tetrahedron: asymmetry (27.08.1999)
Get full text
Journal Article
Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design
Hughes, Norman E., Bleisch, Thomas J., Jones, Scott A., Richardson, Timothy I., Doti, Robert A., Wang, Yong, Stout, Stephanie L., Durst, Gregory L., Chambers, Mark G., Oskins, Jennifer L., Lin, Chaohua, Adams, Lisa A., Page, Todd J., Barr, Robert J., Zink, Richard W., Osborne, Harold, Montrose-Rafizadeh, Chahrzad, Norman, Bryan H.
Published in Bioorganic & medicinal chemistry letters (01.07.2016)
Get full text
Published in Bioorganic & medicinal chemistry letters (01.07.2016)
Journal Article
Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13
Monovich, Lauren G, Tommasi, Ruben A, Fujimoto, Roger A, Blancuzzi, Vincent, Clark, Kirk, Cornell, Wendy D, Doti, Robert, Doughty, John, Fang, James, Farley, David, Fitt, John, Ganu, Vishwas, Goldberg, Ronald, Goldstein, Robert, Lavoie, Stacey, Kulathila, Raviraj, Macchia, William, Parker, David T, Melton, Richard, O’Byrne, Elizabeth, Pastor, Gary, Pellas, Theodore, Quadros, Elizabeth, Reel, Noela, Roland, Dennis M, Sakane, Yumi, Singh, Hem, Skiles, Jerry, Somers, Joseph, Toscano, Karen, Wigg, Andrew, Zhou, Siyuan, Zhu, Lijuan, Shieh, Wen-Chung, Xue, Song, McQuire, Leslie W
Published in Journal of medicinal chemistry (11.06.2009)
Published in Journal of medicinal chemistry (11.06.2009)
Get full text
Journal Article
Carboxy-Substituted Cinnamides: A Novel Series of Potent, Orally Active LTB4 Receptor Antagonists
Greenspan, Paul D, Fujimoto, Roger A, Marshall, Paul J, Raychaudhuri, Anil, Lipson, Kenneth E, Zhou, Huanghai, Doti, Robert A, Coppa, David E, Zhu, Lijuan, Pelletier, Roberta, Uziel-Fusi, Susan, Jackson, Robert H, Chin, Michael H, Kotyuk, Bernard L, Fitt, John J
Published in Journal of medicinal chemistry (14.01.1999)
Published in Journal of medicinal chemistry (14.01.1999)
Get full text
Journal Article
DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS
PFEIFER LANCE ALLEN, NORMAN BRYAN HURST, DOTI ROBERT ANTHONY, BLEISCH THOMAS JOHN
Year of Publication 12.11.2015
Get full text
Year of Publication 12.11.2015
Patent
N-aryl cinnamides : A novel class of rigid and highly potent leukotriene B4 receptor antagonists
GREENSPAN, P. D, MAIN, A. J, JACKSON, R. H, UZIEL-FUSI, S, BHAGWAT, S. S, BARSKY, L. I, DOTI, R. A, ENGLE, A. R, FREY, L. M, ZHOU, H, LIPSON, K. E, CHIN, M. H
Published in Bioorganic & medicinal chemistry letters (01.01.1997)
Published in Bioorganic & medicinal chemistry letters (01.01.1997)
Get full text
Journal Article
DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS
DOTI, ROBERT ANTHONY, PFEIFER, LANCE ALLEN, BLEISCH, THOMAS JOHN, NORMAN, BRYAN HURST
Year of Publication 28.11.2017
Get full text
Year of Publication 28.11.2017
Patent
DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS
BLEISCH, Thomas John, DOTI, Robert Anthony, NORMAN, Bryan Hurst, PFEIFER, Lance Allen
Year of Publication 01.03.2017
Get full text
Year of Publication 01.03.2017
Patent
Dihydropyrido pyrimidine compounds as autotaxin inhibitors
Doti Robert Anthony, Pfeifer Lance Allen, Bleisch Thomas John, Norman Bryan Hurst
Year of Publication 24.01.2017
Get full text
Year of Publication 24.01.2017
Patent
Carboxy-Substituted Cinnamides: A Novel Series of Potent, Orally Active LTB 4 Receptor Antagonists
Greenspan, Paul D., Fujimoto, Roger A., Marshall, Paul J., Raychaudhuri, Anil, Lipson, Kenneth E., Zhou, Huanghai, Doti, Robert A., Coppa, David E., Zhu, Lijuan, Pelletier, Roberta, Uziel-Fusi, Susan, Jackson, Robert H., Chin, Michael H., Kotyuk, Bernard L., Fitt, John J.
Published in Journal of medicinal chemistry (01.01.1999)
Published in Journal of medicinal chemistry (01.01.1999)
Get full text
Journal Article
Dihydropyrido pyrimidine compounds as autotaxin inhibitors
DOTI, ROBERT ANTHONY, PFEIFER, LANCE ALLEN, BLEISCH, THOMAS JOHN, NORMAN, BRYAN HURST
Year of Publication 17.03.2016
Get full text
Year of Publication 17.03.2016
Patent
DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS
DOTI, ROBERT ANTHONY, PFEIFER, LANCE ALLEN, BLEISCH, THOMAS JOHN, NORMAN, BRYAN HURST
Year of Publication 17.02.2016
Get full text
Year of Publication 17.02.2016
Patent
DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS
PFEIFER LANCE ALLEN, NORMAN BRYAN HURST, DOTI ROBERT ANTHONY, BLEISCH THOMAS JOHN
Year of Publication 24.12.2015
Get full text
Year of Publication 24.12.2015
Patent
Dihydropyrido pyrimidine compounds as autotaxin inhibitors
PFEIFER LANCE ALLEN, NORMAN BRYAN HURST, DOTI ROBERT ANTHONY, BLEISCH THOMAS JOHN
Year of Publication 25.11.2015
Get full text
Year of Publication 25.11.2015
Patent
Dihydropyrido pyrimidine compounds as autotaxin inhibitors
DOTI, ROBERT ANTHONY, PFEIFER, LANCE ALLEN, BLEISCH, THOMAS JOHN, NORMAN, BRYAN HURST
Year of Publication 01.10.2015
Get full text
Year of Publication 01.10.2015
Patent
DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS
DOTI, ROBERT ANTHONY, PFEIFER, LANCE ALLEN, BLEISCH, THOMAS JOHN, NORMAN, BRYAN HURST
Year of Publication 16.10.2014
Get full text
Year of Publication 16.10.2014
Patent
DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS
DOTI, ROBERT ANTHONY, PFEIFER, LANCE ALLEN, BLEISCH, THOMAS JOHN, NORMAN, BRYAN HURST
Year of Publication 16.10.2014
Get full text
Year of Publication 16.10.2014
Patent