Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
Lee, Dong I., Zhu, Guangshuo, Sasaki, Takashi, Cho, Gun-Sik, Hamdani, Nazha, Holewinski, Ronald, Jo, Su-Hyun, Danner, Thomas, Zhang, Manling, Rainer, Peter P., Bedja, Djahida, Kirk, Jonathan A., Ranek, Mark J., Dostmann, Wolfgang R., Kwon, Chulan, Margulies, Kenneth B., Van Eyk, Jennifer E., Paulus, Walter J., Takimoto, Eiki, Kass, David A.
Published in Nature (London) (26.03.2015)
Published in Nature (London) (26.03.2015)
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Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart
Miller, Clint L., Cai, Yujun, Oikawa, Masayoshi, Thomas, Tamlyn, Dostmann, Wolfgang R., Zaccolo, Manuela, Fujiwara, Keigi, Yan, Chen
Published in Basic research in cardiology (01.11.2011)
Published in Basic research in cardiology (01.11.2011)
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Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors
Nausch, Lydia W.M, Ledoux, Jonathan, Bonev, Adrian D, Nelson, Mark T, Dostmann, Wolfgang R
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2008)
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Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication
Osborne, Brent W., Wu, Jian, McFarland, Caitlin J., Nickl, Christian K., Sankaran, Banumathi, Casteel, Darren E., Woods, Virgil L., Kornev, Alexandr P., Taylor, Susan S., Dostmann, Wolfgang R.
Published in Structure (London) (07.09.2011)
Published in Structure (London) (07.09.2011)
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Journal Article
Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors
Batchelor, Andrew M., Bartus, Katalin, Reynell, Clare, Constantinou, Sophie, Halvey, Edward J., Held, Kara F., Dostmann, Wolfgang R., Vernon, Jeffrey, Garthwaite, John, Ignarro, Louis J.
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.2010)
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p38 MAPK Activation Elevates Serotonin Transport Activity via a Trafficking-independent, Protein Phosphatase 2A-dependent Process
Zhu, Chong-Bin, Carneiro, Ana M., Dostmann, Wolfgang R., Hewlett, William A., Blakely, Randy D.
Published in The Journal of biological chemistry (22.04.2005)
Published in The Journal of biological chemistry (22.04.2005)
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cGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism
Takimoto, Eiki, Champion, Hunter C, Belardi, Diego, Moslehi, Javid, Mongillo, Marco, Mergia, Evanthia, Montrose, David C, Isoda, Takayoshi, Aufiero, Kate, Zaccolo, Manuela, Dostmann, Wolfgang R, Smith, Carolyn J, Kass, David A
Published in Circulation research (07.01.2005)
Published in Circulation research (07.01.2005)
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Nitric Oxide Promotes Airway Epithelial Wound Repair through Enhanced Activation of MMP-9
Bove, Peter F, Wesley, Umadevi V, Greul, Anne-Katrin, Hristova, Milena, Dostmann, Wolfgang R, van der Vliet, Albert
Published in American journal of respiratory cell and molecular biology (01.02.2007)
Published in American journal of respiratory cell and molecular biology (01.02.2007)
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SERCA2a-phospholamban interaction monitored by an interposed circularly permutated green fluorescent protein
Arnold, Maren E, Dostmann, Wolfgang R, Martin, Jody, Previs, Michael J, Palmer, Bradley, LeWinter, Martin, Meyer, Markus
Published in American journal of physiology. Heart and circulatory physiology (01.06.2021)
Published in American journal of physiology. Heart and circulatory physiology (01.06.2021)
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Oxidation of cysteine 117 stimulates constitutive activation of the type Iα cGMP-dependent protein kinase
Sheehe, Jessica L., Bonev, Adrian D., Schmoker, Anna M., Ballif, Bryan A., Nelson, Mark T., Moon, Thomas M., Dostmann, Wolfgang R.
Published in The Journal of biological chemistry (26.10.2018)
Published in The Journal of biological chemistry (26.10.2018)
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cGMP-dependent protein kinase Iα associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake
Steiner, Jennifer A, Carneiro, Ana MarinD, Wright, Jane, Matthies, Heinrich JG, Prasad, Harish C, Nicki, Christian K, Dostmann, Wolfgang R, Buchanan, Carrie C, Corbin, Jackie D, Francis, Sharron H, Blakely, Randy D
Published in Molecular brain (05.08.2009)
Published in Molecular brain (05.08.2009)
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Inhibition of the chimeric DnaJ‐PKAc enzyme by endogenous inhibitor proteins
Averill, April M., Rehman, Hibba tul, Charles, Joseph W., Dinh, Timothy A., Danyal, Karamatullah, Verschraegen, Claire F., Stein, Gary S., Dostmann, Wolfgang R., Ramsey, Jon E.
Published in Journal of cellular biochemistry (01.08.2019)
Published in Journal of cellular biochemistry (01.08.2019)
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Inhibition of cGMP-Dependent Protein Kinase by the Cell-Permeable Peptide DT-2 Reveals a Novel Mechanism of Vasoregulation
Taylor, Mark S, Okwuchukwuasanya, Chris, Nickl, Christian K, Tegge, Werner, Brayden, Joseph E, Dostmann, Wolfgang R G
Published in Molecular pharmacology (01.05.2004)
Published in Molecular pharmacology (01.05.2004)
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Compartmentalized Phosphodiesterase-2 Activity Blunts β-Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway
Mongillo, Marco, Tocchetti, Carlo G, Terrin, Anna, Lissandron, Valentina, Cheung, York-Fong, Dostmann, Wolfgang R, Pozzan, Tullio, Kass, David A, Paolocci, Nazareno, Houslay, Miles D, Zaccolo, Manuela
Published in Circulation research (03.02.2006)
Published in Circulation research (03.02.2006)
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An N-terminally truncated form of cyclic GMP–dependent protein kinase Iα (PKG Iα) is monomeric and autoinhibited and provides a model for activation
Moon, Thomas M., Sheehe, Jessica L., Nukareddy, Praveena, Nausch, Lydia W., Wohlfahrt, Jessica, Matthews, Dwight E., Blumenthal, Donald K., Dostmann, Wolfgang R.
Published in The Journal of biological chemistry (25.05.2018)
Published in The Journal of biological chemistry (25.05.2018)
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Altered cGMP Dynamics at the Plasma Membrane Contribute to Diarrhea in Ulcerative Colitis
Arora, Kavisha, Sinha, Chandrima, Zhang, Weiqiang, Moon, Chang Suk, Ren, Aixia, Yarlagadda, Sunitha, Dostmann, Wolfgang R, Adebiyi, Adebowale, Haberman, Yael, Denson, Lee A, Wang, Xusheng, Naren, Anjaparavanda P
Published in The American journal of pathology (01.10.2015)
Published in The American journal of pathology (01.10.2015)
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