Regulation of chronic inflammatory and immune processes by extracellular vesicles
Robbins, Paul D, Dorronsoro, Akaitz, Booker, Cori N
Published in The Journal of clinical investigation (01.04.2016)
Published in The Journal of clinical investigation (01.04.2016)
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Journal Article
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Dorronsoro, Akaitz, Lang, Valérie, Ferrin, Izaskun, Fernández-Rueda, Jon, Zabaleta, Lorea, Pérez-Ruiz, Estibaliz, Sepúlveda, Pilar, Trigueros, César
Published in Scientific reports (14.12.2020)
Published in Scientific reports (14.12.2020)
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Journal Article
Identification of HSP90 inhibitors as a novel class of senolytics
Fuhrmann-Stroissnigg, Heike, Ling, Yuan Yuan, Zhao, Jing, McGowan, Sara J., Zhu, Yi, Brooks, Robert W., Grassi, Diego, Gregg, Siobhan Q., Stripay, Jennifer L., Dorronsoro, Akaitz, Corbo, Lana, Tang, Priscilla, Bukata, Christina, Ring, Nadja, Giacca, Mauro, Li, Xuesen, Tchkonia, Tamara, Kirkland, James L., Niedernhofer, Laura J., Robbins, Paul D.
Published in Nature communications (04.09.2017)
Published in Nature communications (04.09.2017)
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Journal Article
HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn's Disease
Gómez-Ferrer, Marta, Amaro-Prellezo, Elena, Dorronsoro, Akaitz, Sánchez-Sánchez, Rafael, Vicente, Ángeles, Cosín-Roger, Jesús, Barrachina, María Dolores, Baquero, María Carmen, Valencia, Jaris, Sepúlveda, Pilar
Published in International journal of molecular sciences (19.10.2021)
Published in International journal of molecular sciences (19.10.2021)
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Journal Article
HIF-1α and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles
Gómez-Ferrer, Marta, Villanueva-Badenas, Estela, Sánchez-Sánchez, Rafael, Sánchez-López, Christian M, Baquero, Maria Carmen, Sepúlveda, Pilar, Dorronsoro, Akaitz
Published in International journal of molecular sciences (26.03.2021)
Published in International journal of molecular sciences (26.03.2021)
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Journal Article
miR-4732-3p in Extracellular Vesicles From Mesenchymal Stromal Cells Is Cardioprotective During Myocardial Ischemia
Sánchez-Sánchez, Rafael, Gómez-Ferrer, Marta, Reinal, Ignacio, Buigues, Marc, Villanueva-Bádenas, Estela, Ontoria-Oviedo, Imelda, Hernándiz, Amparo, González-King, Hernán, Peiró-Molina, Esteban, Dorronsoro, Akaitz, Sepúlveda, Pilar
Published in Frontiers in cell and developmental biology (31.08.2021)
Published in Frontiers in cell and developmental biology (31.08.2021)
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Journal Article
Hypoxia-inducible factor 1 alpha contributes to cardiac healing in mesenchymal stem cells-mediated cardiac repair
Cerrada, Inmaculada, Ruiz-Saurí, Amparo, Carrero, Rubén, Trigueros, César, Dorronsoro, Akaitz, Sanchez-Puelles, Jose María, Diez-Juan, Antonio, Montero, Jose Anastasio, Sepúlveda, Pilar
Published in Stem cells and development (01.02.2013)
Published in Stem cells and development (01.02.2013)
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Journal Article
Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice
Proto, Jonathan D, Lu, Aiping, Dorronsoro, Akaitz, Scibetta, Alex, Robbins, Paul D, Niedernhofer, Laura J, Huard, Johnny
Published in PloS one (22.06.2017)
Published in PloS one (22.06.2017)
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Journal Article
IFNγ Regulates Activated Vδ2+ T Cells through a Feedback Mechanism Mediated by Mesenchymal Stem Cells
Fechter, Karoline, Dorronsoro, Akaitz, Jakobsson, Emma, Ferrin, Izaskun, Lang, Valérie, Sepulveda, Pilar, Pennington, Daniel J, Trigueros, César
Published in PloS one (01.01.2017)
Published in PloS one (01.01.2017)
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Journal Article
Regulation of human bone marrow stromal cell proliferation and differentiation capacity by glucocorticoid receptor and AP‐1 crosstalk
Cárcamo‐Orive, Iván, Gaztelumendi, Ainhoa, Delgado, Jesús, Tejados, Naiara, Dorronsoro, Akaitz, Fernández‐Rueda, Jon, Pennington, Daniel J, Trigueros, César
Published in Journal of bone and mineral research (01.10.2010)
Published in Journal of bone and mineral research (01.10.2010)
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Journal Article
Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation
Bernad, Antonio, Sepúlveda, Pilar, Rodríguez-Borlado, Luis, Dorronsoro, Akaitz, López-Cerdán, Adolfo, García-García, Francisco, Sánchez, Belén, Panadero, Joaquín, Palacios, Itziar, Ontoria-Oviedo, Imelda, Castellano, Delia
Published in Stem cells international (10.10.2020)
Published in Stem cells international (10.10.2020)
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Journal Article
MicroRNA-4732-3p Is Dysregulated in Breast Cancer Patients with Cardiotoxicity, and Its Therapeutic Delivery Protects the Heart from Doxorubicin-Induced Oxidative Stress in Rats
Sánchez-Sánchez, Rafael, Reinal, Ignacio, Peiró-Molina, Esteban, Buigues, Marc, Tejedor, Sandra, Hernándiz, Amparo, Selva, Marta, Hervás, David, Cañada, Antonio J, Dorronsoro, Akaitz, Santaballa, Ana, Salvador, Carmen, Caiment, Florian, Kleinjans, Jos, Martínez-Dolz, Luis, Moscoso, Isabel, Lage, Ricardo, González-Juanatey, José R, Panadero, Joaquín, Aparicio-Puerta, Ernesto, Bernad, Antonio, Sepúlveda, Pilar
Published in Antioxidants (30.09.2022)
Published in Antioxidants (30.09.2022)
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Journal Article
Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs
Nauman, Grace, Danzl, Nichole M, Lee, Jaeyop, Borsotti, Chiara, Madley, Rachel, Fu, Jianing, Hölzl, Markus A, Dahmani, Alexander, Dorronsoro Gonzalez, Akaitz, Chavez, Éstefania, Campbell, Sean R, Yang, Suxiao, Satwani, Prakash, Liu, Kang, Sykes, Megan
Published in The Journal of immunology (1950) (01.04.2022)
Published in The Journal of immunology (1950) (01.04.2022)
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Journal Article
NR5A2/LRH-1 regulates the PTGS2-PGE2-PTGER1 pathway contributing to pancreatic islet survival and function
Martin Vázquez, Eugenia, Cobo-Vuilleumier, Nadia, Araujo Legido, Raquel, Marín-Cañas, Sandra, Nola, Emanuele, Dorronsoro, Akaitz, López Bermudo, Lucia, Crespo, Alejandra, Romero-Zerbo, Silvana Y., García-Fernández, Maria, Martin Montalvo, Alejandro, Rojas, Anabel, Comaills, Valentine, Bérmudez-Silva, Francisco J., Gannon, Maureen, Martin, Franz, Eizirik, Decio, Lorenzo, Petra I., Gauthier, Benoit R.
Published in iScience (20.05.2022)
Published in iScience (20.05.2022)
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Journal Article
Corrigendum to “Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation”
Ontoria-Oviedo, Imelda, Palacios, Itziar, Panadero, Joaquín, Sánchez, Belén, García-García, Francisco, López-Cerdán, Adolfo, Dorronsoro, Akaitz, Castellano, Delia, Rodríguez-Borlado, Luis, Bernad, Antonio, Sepúlveda, Pilar
Published in Stem cells international (2022)
Published in Stem cells international (2022)
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Journal Article
Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility
Ontoria-Oviedo, Imelda, Dorronsoro, Akaitz, Sánchez, Rafael, Ciria, Maria, Gómez-Ferrer, Marta, Buigues, Marc, Grueso, Elena, Tejedor, Sandra, García-García, Francisco, González-King, Hernán, Garcia, Nahuel A, Peiró-Molina, Esteban, Sepúlveda, Pilar
Published in Frontiers in cardiovascular medicine (25.10.2018)
Published in Frontiers in cardiovascular medicine (25.10.2018)
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Journal Article
Quantitative Analysis of Cellular Senescence in Culture and In Vivo
Zhao, Jing, Fuhrmann-Stroissnigg, Heike, Gurkar, Aditi U, Flores, Rafael R, Dorronsoro, Akaitz, Stolz, Donna B, St Croix, Claudette M, Niedernhofer, Laura J, Robbins, Paul D
Published in Current protocols in cytometry (01.01.2017)
Published in Current protocols in cytometry (01.01.2017)
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Journal Article
Human Mesenchymal Stromal Cell-Mediated Immunoregulation: Mechanisms of Action and Clinical Applications
Fernández-Rueda, Jon, Ferrin, Izaskun, Dorronsoro, Akaitz, Trigueros, César, Jakobsson, Emma, Salcedo, Juan Manuel, Fechter, Karoline
Published in Bone Marrow Research (01.01.2013)
Published in Bone Marrow Research (01.01.2013)
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Journal Article
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
Zhu, Yi, Tchkonia, Tamara, Pirtskhalava, Tamar, Gower, Adam C., Ding, Husheng, Giorgadze, Nino, Palmer, Allyson K., Ikeno, Yuji, Hubbard, Gene B., Lenburg, Marc, O'Hara, Steven P., LaRusso, Nicholas F., Miller, Jordan D., Roos, Carolyn M., Verzosa, Grace C., LeBrasseur, Nathan K., Wren, Jonathan D., Farr, Joshua N., Khosla, Sundeep, Stout, Michael B., McGowan, Sara J., Fuhrmann‐Stroissnigg, Heike, Gurkar, Aditi U., Zhao, Jing, Colangelo, Debora, Dorronsoro, Akaitz, Ling, Yuan Yuan, Barghouthy, Amira S., Navarro, Diana C., Sano, Tokio, Robbins, Paul D., Niedernhofer, Laura J., Kirkland, James L.
Published in Aging cell (01.08.2015)
Published in Aging cell (01.08.2015)
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Journal Article
Mesenchymal stem cell‐derived extracellular vesicles reduce senescence and extend health span in mouse models of aging
Dorronsoro, Akaitz, Santiago, Fernando E., Grassi, Diego, Zhang, Tianpeng, Lai, Ruenn Chai, McGowan, Sara J., Angelini, Luise, Lavasani, Mitra, Corbo, Lana, Lu, Aiping, Brooks, Robert W., Garcia‐Contreras, Marta, Stolz, Donna B., Amelio, Antonio, Boregowda, Siddaraju V., Fallahi, Mohammad, Reich, Adrian, Ricordi, Camillo, Phinney, Donald G., Huard, Johnny, Lim, Sai Kiang, Niedernhofer, Laura J., Robbins, Paul D.
Published in Aging cell (01.04.2021)
Published in Aging cell (01.04.2021)
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Journal Article