Effects of Cytochrome P450 Inhibition and Induction on the Phenotyping Metrics of the Basel Cocktail: A Randomized Crossover Study
Derungs, Adrian, Donzelli, Massimiliano, Berger, Benjamin, Noppen, Christoph, Krähenbühl, Stephan, Haschke, Manuel
Published in Clinical pharmacokinetics (01.01.2016)
Published in Clinical pharmacokinetics (01.01.2016)
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Journal Article
The Basel Cocktail for Simultaneous Phenotyping of Human Cytochrome P450 Isoforms in Plasma, Saliva and Dried Blood Spots
Donzelli, Massimiliano, Derungs, Adrian, Serratore, Maria-Giovanna, Noppen, Christoph, Nezic, Lana, Krähenbühl, Stephan, Haschke, Manuel
Published in Clinical pharmacokinetics (01.03.2014)
Published in Clinical pharmacokinetics (01.03.2014)
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Journal Article
Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail
Berger, Benjamin, Donzelli, Massimiliano, Maseneni, Swarna, Boess, Franziska, Roth, Adrian, Krähenbühl, Stephan, Haschke, Manuel
Published in Frontiers in pharmacology (21.11.2016)
Published in Frontiers in pharmacology (21.11.2016)
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Journal Article
Using zebrafish to model erythroid lineage toxicity and regeneration
Lenard, Anna, Alghisi, Elisa, Daff, Hamina, Donzelli, Massimiliano, McGinnis, Claudia, Lengerke, Claudia
Published in Haematologica (Roma) (01.05.2016)
Published in Haematologica (Roma) (01.05.2016)
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Journal Article
Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
Ekiciler, Aynur, Chen, Wen Li Kelly, Bo, Yan, Pugliano, Alessandra, Donzelli, Massimiliano, Parrott, Neil, Umehara, Kenichi
Published in Drug metabolism and disposition (01.03.2023)
Published in Drug metabolism and disposition (01.03.2023)
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Journal Article
Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein
Fischer, Holger, Ullah, Mohammed, de la Cruz, Cecile C, Hunsaker, Thomas, Senn, Claudia, Wirz, Thomas, Wagner, Björn, Draganov, Dragomir, Vazvaei, Faye, Donzelli, Massimiliano, Paehler, Axel, Merchant, Mark, Yu, Li
Published in Neuro-oncology (Charlottesville, Va.) (09.06.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.06.2020)
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Journal Article
The molecular basis for the prolonged blood circulation of lipidated incretin peptides: Peptide oligomerization or binding to serum albumin?
Wang, Ying, Lomakin, Aleksey, Kanai, Sonoko, Alex, Rainer, Belli, Sara, Donzelli, Massimiliano, Benedek, George B.
Published in Journal of controlled release (10.11.2016)
Published in Journal of controlled release (10.11.2016)
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Journal Article
Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions
Duthaler, Urs, Berger, Benjamin, Erb, Stefan, Battegay, Manuel, Letang, Emili, Gaugler, Stefan, Natamatungiro, Alex, Mnzava, Dorcas, Donzelli, Massimiliano, Krähenbühl, Stephan, Haschke, Manuel
Published in Journal of antimicrobial chemotherapy (01.10.2018)
Published in Journal of antimicrobial chemotherapy (01.10.2018)
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Journal Article
Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination
Hysek, Cédric M., Simmler, Linda D., Schillinger, Nathalie, Meyer, Nicole, Schmid, Yasmin, Donzelli, Massimiliano, Grouzmann, Eric, Liechti, Matthias E.
Published in The international journal of neuropsychopharmacology (01.03.2014)
Published in The international journal of neuropsychopharmacology (01.03.2014)
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Journal Article
Toxicity of thienopyridines on human neutrophil granulocytes and lymphocytes
Maseneni, Swarna, Donzelli, Massimiliano, Brecht, Karin, Krähenbühl, Stephan
Published in Toxicology (Amsterdam) (07.06.2013)
Published in Toxicology (Amsterdam) (07.06.2013)
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Journal Article
Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib
Morcos, Peter N., Cleary, Yumi, Sturm‐Pellanda, Carolina, Guerini, Elena, Abt, Markus, Donzelli, Massimiliano, Vazvaei, Faye, Balas, Bogdana, Parrott, Neil, Yu, Li
Published in Journal of clinical pharmacology (01.12.2018)
Published in Journal of clinical pharmacology (01.12.2018)
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Journal Article
Hepatic toxicity of dronedarone in mice: Role of mitochondrial β-oxidation
Felser, Andrea, Stoller, Andrea, Morand, Réjane, Schnell, Dominik, Donzelli, Massimiliano, Terracciano, Luigi, Bouitbir, Jamal, Krähenbühl, Stephan
Published in Toxicology (Amsterdam) (02.09.2014)
Published in Toxicology (Amsterdam) (02.09.2014)
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Journal Article
Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction
Morand, Réjane, Donzelli, Massimiliano, Haschke, Manuel, Krähenbühl, Stephan
Published in Analytical and bioanalytical chemistry (01.11.2013)
Published in Analytical and bioanalytical chemistry (01.11.2013)
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Journal Article
α₁-Adrenergic receptors contribute to the acute effects of 3,4-methylenedioxymethamphetamine in humans
Hysek, Cédric M, Fink, Anja E, Simmler, Linda D, Donzelli, Massimiliano, Grouzmann, Eric, Liechti, Matthias E
Published in Journal of clinical psychopharmacology (01.10.2013)
Published in Journal of clinical psychopharmacology (01.10.2013)
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Journal Article
Role of Cytochrome P450 3A4 and 1A2 Phenotyping in Patients with Advanced Non‐small‐Cell Lung Cancer Receiving Erlotinib Treatment
Parra‐Guillen, Zinnia P., Berger, Peter B., Haschke, Manuel, Donzelli, Massimiliano, Winogradova, Daria, Pfister, Bogumila, Früh, Martin, Gillessen, Silke, Krähenbühl, Stephan, Kloft, Charlotte, Joerger, Markus
Published in Basic & clinical pharmacology & toxicology (01.10.2017)
Published in Basic & clinical pharmacology & toxicology (01.10.2017)
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Journal Article
Analytical interference of 4-hydroxy-3-methoxymethamphetamine with the measurement of plasma free normetanephrine by ultra-high pressure liquid chromatography–tandem mass spectrometry
Dunand, Marielle, Donzelli, Massimiliano, Rickli, Anna, Hysek, Cédric M., Liechti, Matthias E., Grouzmann, Eric
Published in Clinical biochemistry (01.08.2014)
Published in Clinical biochemistry (01.08.2014)
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Journal Article
Effects of the α₂-adrenergic agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine in healthy volunteers
Hysek, Cédric M, Brugger, Robin, Simmler, Linda D, Bruggisser, Marcel, Donzelli, Massimiliano, Grouzmann, Eric, Hoener, Marius C, Liechti, Matthias E
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
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Journal Article
Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans
Morand, Réjane, Todesco, Liliane, Donzelli, Massimiliano, Fischer-Barnicol, David, Mullen, Peter J, Krähenbühl, Stephan
Published in Therapeutic drug monitoring (01.08.2012)
Published in Therapeutic drug monitoring (01.08.2012)
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Journal Article
Effects of the α 2 -Adrenergic Agonist Clonidine on the Pharmacodynamics and Pharmacokinetics of 3,4-Methylenedioxymethamphetamine in Healthy Volunteers
Hysek, Cédric M., Brugger, Robin, Simmler, Linda D., Bruggisser, Marcel, Donzelli, Massimiliano, Grouzmann, Eric, Hoener, Marius C., Liechti, Matthias E.
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
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