Advances in Industrial Biotechnology Using CRISPR-Cas Systems
Donohoue, Paul D., Barrangou, Rodolphe, May, Andrew P.
Published in Trends in biotechnology (Regular ed.) (01.02.2018)
Published in Trends in biotechnology (Regular ed.) (01.02.2018)
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Journal Article
Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality
Briner, Alexandra E., Donohoue, Paul D., Gomaa, Ahmed A., Selle, Kurt, Slorach, Euan M., Nye, Christopher H., Haurwitz, Rachel E., Beisel, Chase L., May, Andrew P., Barrangou, Rodolphe
Published in Molecular cell (23.10.2014)
Published in Molecular cell (23.10.2014)
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Journal Article
Mapping the genomic landscape of CRISPR–Cas9 cleavage
Cameron, Peter, Fuller, Chris K, Donohoue, Paul D, Jones, Brittnee N, Thompson, Matthew S, Carter, Matthew M, Gradia, Scott, Vidal, Bastien, Garner, Elizabeth, Slorach, Euan M, Lau, Elaine, Banh, Lynda M, Lied, Alexandra M, Edwards, Leslie S, Settle, Alexander H, Capurso, Daniel, Llaca, Victor, Deschamps, Stéphane, Cigan, Mark, Young, Joshua K, May, Andrew P
Published in Nature methods (01.06.2017)
Published in Nature methods (01.06.2017)
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Journal Article
Structural basis for Cas9 off-target activity
Pacesa, Martin, Lin, Chun-Han, Cléry, Antoine, Saha, Aakash, Arantes, Pablo R, Bargsten, Katja, Irby, Matthew J, Allain, Frédéric H-T, Palermo, Giulia, Cameron, Peter, Donohoue, Paul D, Jinek, Martin
Published in Cell (27.10.2022)
Published in Cell (27.10.2022)
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Journal Article
NmeCas9 is an intrinsically high-fidelity genome-editing platform
Amrani, Nadia, Gao, Xin D, Liu, Pengpeng, Edraki, Alireza, Mir, Aamir, Ibraheim, Raed, Gupta, Ankit, Sasaki, Kanae E, Wu, Tong, Donohoue, Paul D, Settle, Alexander H, Lied, Alexandra M, McGovern, Kyle, Fuller, Chris K, Cameron, Peter, Fazzio, Thomas G, Zhu, Lihua Julie, Wolfe, Scot A, Sontheimer, Erik J
Published in Genome Biology (05.12.2018)
Published in Genome Biology (05.12.2018)
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Journal Article
Harnessing type I CRISPR–Cas systems for genome engineering in human cells
Cameron, Peter, Coons, Mary M., Klompe, Sanne E., Lied, Alexandra M., Smith, Stephen C., Vidal, Bastien, Donohoue, Paul D., Rotstein, Tomer, Kohrs, Bryan W., Nyer, David B., Kennedy, Rachel, Banh, Lynda M., Williams, Carolyn, Toh, Mckenzi S., Irby, Matthew J., Edwards, Leslie S., Lin, Chun-Han, Owen, Arthur L. G., Künne, Tim, van der Oost, John, Brouns, Stan J. J., Slorach, Euan M., Fuller, Chris K., Gradia, Scott, Kanner, Steven B., May, Andrew P., Sternberg, Samuel H.
Published in Nature biotechnology (01.12.2019)
Published in Nature biotechnology (01.12.2019)
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Journal Article
Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells
Donohoue, Paul D., Pacesa, Martin, Lau, Elaine, Vidal, Bastien, Irby, Matthew J., Nyer, David B., Rotstein, Tomer, Banh, Lynda, Toh, Mckenzi S., Gibson, Jason, Kohrs, Bryan, Baek, Kevin, Owen, Arthur L.G., Slorach, Euan M., van Overbeek, Megan, Fuller, Christopher K., May, Andrew P., Jinek, Martin, Cameron, Peter
Published in Molecular cell (02.09.2021)
Published in Molecular cell (02.09.2021)
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Journal Article
Author Correction: Mapping the genomic landscape of CRISPR–Cas9 cleavage
Cameron, Peter, Fuller, Chris K., Donohoue, Paul D., Jones, Brittnee N., Thompson, Matthew S., Carter, Matthew M., Gradia, Scott, Vidal, Bastien, Garner, Elizabeth, Slorach, Euan M., Lau, Elaine, Banh, Lynda M., Lied, Alexandra M., Edwards, Leslie S., Settle, Alexander H., Capurso, Daniel, Llaca, Victor, Deschamps, Stéphane, Cigan, Mark, Young, Joshua K., May, Andrew P.
Published in Nature methods (01.12.2023)
Published in Nature methods (01.12.2023)
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Journal Article
Allogeneic chimeric antigen receptor-T cells with CRISPR-disrupted programmed death-1 checkpoint exhibit enhanced functional fitness
Lau, Elaine, Kwong, George, Fowler, Tristan W., Sun, Bee-Chun, Donohoue, Paul D., Davis, Ryan T., Bryan, Mara, McCawley, Shannon, Clarke, Starlynn C., Williams, Carolyn, Banh, Lynda, Irby, Matthew, Edwards, Leslie, Storlie, Meghan, Kohrs, Bryan, Lilley, Graham W.J., Smith, Stephen C., Gradia, Scott, Fuller, Chris K., Skoble, Justin, Garner, Elizabeth, van Overbeek, Megan, Kanner, Steven B.
Published in Cytotherapy (Oxford, England) (01.07.2023)
Published in Cytotherapy (Oxford, England) (01.07.2023)
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Journal Article
High-specificity CRISPR-mediated genome engineering in anti-BCMA allogeneic CAR T cells suppresses allograft rejection in preclinical models
Degagné, Émilie, Donohoue, Paul D, Roy, Suparna, Scherer, Jessica, Fowler, Tristan W, Davis, Ryan T, Reyes, Gustavo A, Kwong, George, Stanaway, Morena, Larroca Vicena, Vanina, Mutha, Devin, Guo, Raymond, Edwards, Leslie, Schilling, Benjamin, Shaw, McKay, Smith, Stephen C, Kohrs, Bryan, Kufeldt, Heinrich J, Churchward, Glen, Ruan, Finey, Nyer, David B, McSweeney, Kyle, Irby, Matthew J, Fuller, Christopher K, Banh, Lynda, Toh, Mckenzi S, Thompson, Matthew, Owen, Arthur L G, An, Zili, Gradia, Scott, Skoble, Justin, Bryan, Mara, Garner, Elizabeth, Kanner, Steven B
Published in Cancer immunology research (02.04.2024)
Published in Cancer immunology research (02.04.2024)
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Identification of Formyl Kynurenine Formamidase and Kynurenine Aminotransferase from Saccharomyces cerevisiae Using Crystallographic, Bioinformatic and Biochemical Evidence
Wogulis, Mark, Chew, Erin R, Donohoue, Paul D, Wilson, David K
Published in Biochemistry (Easton) (12.02.2008)
Published in Biochemistry (Easton) (12.02.2008)
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Journal Article
Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform
Enquist-Newman, Maria, Faust, Ann Marie E., Bravo, Daniel D., Santos, Christine Nicole S., Raisner, Ryan M., Hanel, Arthur, Sarvabhowman, Preethi, Le, Chi, Regitsky, Drew D., Cooper, Susan R., Peereboom, Lars, Clark, Alana, Martinez, Yessica, Goldsmith, Joshua, Cho, Min Y., Donohoue, Paul D., Luo, Lily, Lamberson, Brigit, Tamrakar, Pramila, Kim, Edward J., Villari, Jeffrey L., Gill, Avinash, Tripathi, Shital A., Karamchedu, Padma, Paredes, Carlos J., Rajgarhia, Vineet, Kotlar, Hans Kristian, Bailey, Richard B., Miller, Dennis J., Ohler, Nicholas L., Swimmer, Candace, Yoshikuni, Yasuo
Published in Nature (London) (09.01.2014)
Published in Nature (London) (09.01.2014)
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