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Published in PLoS genetics (01.06.2011)
Published in PLoS genetics (01.06.2011)
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Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies
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Published in Nature communications (23.11.2022)
Published in Nature communications (23.11.2022)
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AKT mutant allele-specific activation dictates pharmacologic sensitivities
Shrestha Bhattarai, Tripti, Shamu, Tambudzai, Gorelick, Alexander N., Chang, Matthew T., Chakravarty, Debyani, Gavrila, Elena I., Donoghue, Mark T. A., Gao, JianJong, Patel, Swati, Gao, Sizhi Paul, Reynolds, Margaret H., Phillips, Sarah M., Soumerai, Tara, Abida, Wassim, Hyman, David M., Schram, Alison M., Solit, David B., Smyth, Lillian M., Taylor, Barry S.
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Genome doubling shapes the evolution and prognosis of advanced cancers
Bielski, Craig M., Zehir, Ahmet, Penson, Alexander V., Donoghue, Mark T. A., Chatila, Walid, Armenia, Joshua, Chang, Matthew T., Schram, Alison M., Jonsson, Philip, Bandlamudi, Chaitanya, Razavi, Pedram, Iyer, Gopa, Robson, Mark E., Stadler, Zsofia K., Schultz, Nikolaus, Baselga, Jose, Solit, David B., Hyman, David M., Berger, Michael F., Taylor, Barry S.
Published in Nature genetics (01.08.2018)
Published in Nature genetics (01.08.2018)
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Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy
Walmsley, Charlotte S., Jonsson, Philip, Cheng, Michael L., McBride, Sean, Kaeser, Christopher, Vargas, Herbert Alberto, Laudone, Vincent, Taylor, Barry S., Kappagantula, Rajya, Baez, Priscilla, Richards, Allison L., Noronha, Anne Marie, Perera, Dilmi, Berger, Michael, Solit, David B., Iacobuzio-Donahue, Christine A., Scher, Howard I., Donoghue, Mark T. A., Abida, Wassim, Schram, Alison M.
Published in NPJ precision oncology (14.02.2024)
Published in NPJ precision oncology (14.02.2024)
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Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer
Chatila, Walid K., Kim, Jin K., Walch, Henry, Marco, Michael R., Chen, Chin-Tung, Wu, Fan, Omer, Dana M., Khalil, Danny N., Ganesh, Karuna, Qu, Xuan, Luthra, Anisha, Choi, Seo-Hyun, Ho, Yu-Jui, Kundra, Ritika, Groves, Katharine I., Chow, Oliver S., Cercek, Andrea, Weiser, Martin R., Widmar, Maria, Wei, Iris H., Pappou, Emmanouil P., Nash, Garrett M., Paty, Philip B., Shi, Qian, Vakiani, Efsevia, Duygu Selcuklu, S., Donoghue, Mark T. A., Solit, David B., Berger, Michael F., Shia, Jinru, Pelossof, Raphael, Romesser, Paul B., Yaeger, Rona, Smith, J. Joshua, Schultz, Nikolaus, Sanchez-Vega, Francisco, Garcia-Aguilar, Julio
Published in Nature medicine (01.08.2022)
Published in Nature medicine (01.08.2022)
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Selective Methylation of Histone H3 Variant H3.1 Regulates Heterochromatin Replication
Jacob, Yannick, Bergamin, Elisa, Donoghue, Mark T. A., Mongeon, Vanessa, LeBlanc, Chantal, Voigt, Philipp, Underwood, Charles J., Brunzelle, Joseph S., Michaels, Scott D., Reinberg, Danny, Couture, Jean-François, Martienssen, Robert A.
Published in Science (American Association for the Advancement of Science) (14.03.2014)
Published in Science (American Association for the Advancement of Science) (14.03.2014)
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phylogenetic approach to test for evidence of parental conflict or gene duplications associated with protein-encoding imprinted orthologous genes in placental mammals
O'Connell, Mary J, Loughran, Noeleen B, Walsh, Thomas A, Donoghue, Mark T. A, Schmid, Karl J, Spillane, Charles
Published in Mammalian genome (01.10.2010)
Published in Mammalian genome (01.10.2010)
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Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma
D’Angelo, Sandra P., Richards, Allison L., Conley, Anthony P., Woo, Hyung Jun, Dickson, Mark A., Gounder, Mrinal, Kelly, Ciara, Keohan, Mary Louise, Movva, Sujana, Thornton, Katherine, Rosenbaum, Evan, Chi, Ping, Nacev, Benjamin, Chan, Jason E., Slotkin, Emily K., Kiesler, Hannah, Adamson, Travis, Ling, Lilan, Rao, Pavitra, Patel, Shreyaskumar, Livingston, Jonathan A., Singer, Samuel, Agaram, Narasimhan P., Antonescu, Cristina R., Koff, Andrew, Erinjeri, Joseph P., Hwang, Sinchun, Qin, Li-Xuan, Donoghue, Mark T. A., Tap, William D.
Published in Nature communications (16.06.2022)
Published in Nature communications (16.06.2022)
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Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory behavior in pituitary neuroendocrine tumors
Lin, Andrew L., Rudneva, Vasilisa A., Richards, Allison L., Zhang, Yanming, Woo, Hyung Jun, Cohen, Marc, Tisnado, Jamie, Majd, Nazanin, Wardlaw, Sharon L., Page-Wilson, Gabrielle, Sengupta, Soma, Chow, Frances, Goichot, Bernard, Ozer, Byram H., Dietrich, Jorg, Nachtigall, Lisa, Desai, Arati, Alano, Tina, Ogilive, Shahiba, Solit, David B., Bale, Tejus A., Rosenblum, Marc, Donoghue, Mark T. A., Geer, Eliza B., Tabar, Viviane
Published in Acta neuropathologica (01.06.2024)
Published in Acta neuropathologica (01.06.2024)
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Molecular adaptation of telomere associated genes in mammals
Morgan, Claire C, Mc Cartney, Ann M, Donoghue, Mark T A, Loughran, Noeleen B, Spillane, Charles, Teeling, Emma C, O'Connell, Mary J
Published in BMC evolutionary biology (15.11.2013)
Published in BMC evolutionary biology (15.11.2013)
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Avelumab Plus Talazoparib in Patients With BRCA1/2- or ATM-Altered Advanced Solid Tumors: Results From JAVELIN BRCA/ATM, an Open-Label, Multicenter, Phase 2b, Tumor-Agnostic Trial
Schram, Alison M, Colombo, Nicoletta, Arrowsmith, Edward, Narayan, Vivek, Yonemori, Kan, Scambia, Giovanni, Zelnak, Amelia, Bauer, Todd M, Jin, Ning, Ulahannan, Susanna V, Colleoni, Marco, Aftimos, Philippe, Donoghue, Mark T A, Rosen, Ezra, Rudneva, Vasilisa A, Telli, Melinda L, Domchek, Susan M, Galsky, Matthew D, Hoyle, Margaret, Chappey, Colombe, Stewart, Ross, Blake-Haskins, John A, Yap, Timothy A
Published in JAMA oncology (01.01.2023)
Published in JAMA oncology (01.01.2023)
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Identification of imprinted genes subject to parent-of-origin specific expression in Arabidopsis thaliana seeds
McKeown, Peter C, Laouielle-Duprat, Sylvia, Prins, Pjotr, Wolff, Philip, Schmid, Marc W, Donoghue, Mark T A, Fort, Antoine, Duszynska, Dorota, Comte, Aurélie, Lao, Nga Thi, Wennblom, Trevor J, Smant, Geert, Köhler, Claudia, Grossniklaus, Ueli, Spillane, Charles
Published in BMC plant biology (12.08.2011)
Published in BMC plant biology (12.08.2011)
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Transgenerational effects of inter-ploidy cross direction on reproduction and F2 seed development of Arabidopsis thaliana F1 hybrid triploids
Duszynska, Dorota, Vilhjalmsson, Bjarni, Castillo Bravo, Rosa, Swamidatta, Sandesh, Juenger, Thomas E., Donoghue, Mark T. A., Comte, Aurélie, Nordborg, Magnus, Sharbel, Timothy F., Brychkova, Galina, McKeown, Peter C., Spillane, Charles
Published in Plant reproduction (01.09.2019)
Published in Plant reproduction (01.09.2019)
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Computational Identification and Evolutionary Relationships of the MicroRNA Gene Cluster miR-71/2 in Protostomes
de Souza Gomes, Matheus, Donoghue, Mark T. A., Muniyappa, MohanKumar, Pereira, Roberta Verciano, Guerra-Sá, Renata, Spillane, Charles
Published in Journal of molecular evolution (01.06.2013)
Published in Journal of molecular evolution (01.06.2013)
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Uncovering Differentially Methylated Regions (DMRs) in a Salt-Tolerant Rice Variety under Stress: One Step towards New Regulatory Regions for Enhanced Salt Tolerance
Ferreira, Liliana J, Donoghue, Mark T A, Barros, Pedro, Saibo, Nelson J, Santos, Ana Paula, Oliveira, M Margarida
Published in Epigenomes (18.01.2019)
Published in Epigenomes (18.01.2019)
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Evolutionary origins of Brassicaceae specific genes in Arabidopsis thaliana
Donoghue, Mark Ta, Keshavaiah, Channa, Swamidatta, Sandesh H, Spillane, Charles
Published in BMC evolutionary biology (18.02.2011)
Published in BMC evolutionary biology (18.02.2011)
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Tumour lineage shapes BRCA-mediated phenotypes
Jonsson, Philip, Bandlamudi, Chaitanya, Cheng, Michael L., Srinivasan, Preethi, Chavan, Shweta S., Friedman, Noah D., Rosen, Ezra Y., Richards, Allison L., Bouvier, Nancy, Selcuklu, S. Duygu, Bielski, Craig M., Abida, Wassim, Mandelker, Diana, Birsoy, Ozge, Zhang, Liying, Zehir, Ahmet, Donoghue, Mark T. A., Baselga, José, Offit, Kenneth, Scher, Howard I., O’Reilly, Eileen M., Stadler, Zsofia K., Schultz, Nikolaus, Socci, Nicholas D., Viale, Agnes, Ladanyi, Marc, Robson, Mark E., Hyman, David M., Berger, Michael F., Solit, David B., Taylor, Barry S.
Published in Nature (London) (01.07.2019)
Published in Nature (London) (01.07.2019)
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The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers
Razavi, Pedram, Chang, Matthew T., Xu, Guotai, Bandlamudi, Chaitanya, Ross, Dara S., Vasan, Neil, Cai, Yanyan, Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Penson, Alexander, Shen, Ronglai, Pareja, Fresia, Kundra, Ritika, Middha, Sumit, Cheng, Michael L., Zehir, Ahmet, Kandoth, Cyriac, Patel, Ruchi, Huberman, Kety, Smyth, Lillian M., Jhaveri, Komal, Modi, Shanu, Traina, Tiffany A., Dang, Chau, Zhang, Wen, Weigelt, Britta, Li, Bob T., Ladanyi, Marc, Hyman, David M., Schultz, Nikolaus, Robson, Mark E., Hudis, Clifford, Brogi, Edi, Viale, Agnes, Norton, Larry, Dickler, Maura N., Berger, Michael F., Iacobuzio-Donahue, Christine A., Chandarlapaty, Sarat, Scaltriti, Maurizio, Reis-Filho, Jorge S., Solit, David B., Taylor, Barry S., Baselga, José
Published in Cancer cell (10.09.2018)
Published in Cancer cell (10.09.2018)
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The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer
Schoenfeld, Adam J, Bandlamudi, Chai, Lavery, Jessica A, Montecalvo, Joseph, Namakydoust, Azadeh, Rizvi, Hira, Egger, Jacklynn, Concepcion, Carla P, Paul, Sonal, Arcila, Maria E, Daneshbod, Yahya, Chang, Jason, Sauter, Jennifer L, Beras, Amanda, Ladanyi, Marc, Jacks, Tyler, Rudin, Charles M, Taylor, Barry S, Donoghue, Mark T A, Heller, Glenn, Hellmann, Matthew D, Rekhtman, Natasha, Riely, Gregory J
Published in Clinical cancer research (01.11.2020)
Published in Clinical cancer research (01.11.2020)
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