In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration
Choi, Elliot H, Suh, Susie, Foik, Andrzej T, Leinonen, Henri, Newby, Gregory A, Gao, Xin D, Banskota, Samagya, Hoang, Thanh, Du, Samuel W, Dong, Zhiqian, Raguram, Aditya, Kohli, Sajeev, Blackshaw, Seth, Lyon, David C, Liu, David R, Palczewski, Krzysztof
Published in Nature communications (05.04.2022)
Published in Nature communications (05.04.2022)
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Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing
Suh, Susie, Choi, Elliot H, Leinonen, Henri, Foik, Andrzej T, Newby, Gregory A, Yeh, Wei-Hsi, Dong, Zhiqian, Kiser, Philip D, Lyon, David C, Liu, David R, Palczewski, Krzysztof
Published in Nature biomedical engineering (01.02.2021)
Published in Nature biomedical engineering (01.02.2021)
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Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye
Palczewska, Grazyna, Dong, Zhiqian, Golczak, Marcin, Hunter, Jennifer J, Williams, David R, Alexander, Nathan S, Palczewski, Krzysztof
Published in Nature medicine (01.07.2014)
Published in Nature medicine (01.07.2014)
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Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice
Maeda, Akiko, Palczewska, Grazyna, Golczak, Marcin, Kohno, Hideo, Dong, Zhiqian, Maeda, Tadao, Palczewski, Krzysztof
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
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Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition
Sander, Christopher L, Sears, Avery E, Pinto, Antonio F M, Choi, Elliot H, Kahremany, Shirin, Gao, Fangyuan, Salom, David, Jin, Hui, Pardon, Els, Suh, Susie, Dong, Zhiqian, Steyaert, Jan, Saghatelian, Alan, Skowronska-Krawczyk, Dorota, Kiser, Philip D, Palczewski, Krzysztof
Published in The Journal of cell biology (02.08.2021)
Published in The Journal of cell biology (02.08.2021)
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Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia
Tworak, Aleksander, Kolesnikov, Alexander V., Hong, John D., Choi, Elliot H., Luu, Jennings C., Palczewska, Grazyna, Dong, Zhiqian, Lewandowski, Dominik, Brooks, Matthew J., Campello, Laura, Swaroop, Anand, Kiser, Philip D., Kefalov, Vladimir J., Palczewski, Krzysztof
Published in Cell reports (Cambridge) (29.08.2023)
Published in Cell reports (Cambridge) (29.08.2023)
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A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models
Leinonen, Henri, Zhang, Jianye, Occelli, Laurence M., Seemab, Umair, Choi, Elliot H., L.P. Marinho, Luis Felipe, Querubin, Janice, Kolesnikov, Alexander V., Galinska, Anna, Kordecka, Katarzyna, Hoang, Thanh, Lewandowski, Dominik, Lee, Timothy T., Einstein, Elliott E., Einstein, David E., Dong, Zhiqian, Kiser, Philip D., Blackshaw, Seth, Kefalov, Vladimir J., Tabaka, Marcin, Foik, Andrzej, Petersen-Jones, Simon M., Palczewski, Krzysztof
Published in Nature communications (15.07.2024)
Published in Nature communications (15.07.2024)
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A novel human disease with abnormal prion protein sensitive to protease
Gambetti, Pierluigi, Dong, Zhiqian, Yuan, Jue, Xiao, Xiangzhu, Zheng, Mengjie, Alshekhlee, Amer, Castellani, Rudy, Cohen, Mark, Barria, Marcelo A., Gonzalez-Romero, D., Belay, Ermias D., Schonberger, Lawrence B., Marder, Karen, Harris, Carrie, Burke, James R., Montine, Thomas, Wisniewski, Thomas, Dickson, Dennis W., Soto, Claudio, Hulette, Christine M., Mastrianni, James A., Kong, Qingzhong, Zou, Wen-Quan
Published in Annals of neurology (01.06.2008)
Published in Annals of neurology (01.06.2008)
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MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice
Sundermeier, Thomas R, Sakami, Sanae, Sahu, Bhubanananda, Howell, Scott J, Gao, Songqi, Dong, Zhiqian, Golczak, Marcin, Maeda, Akiko, Palczewski, Krzysztof
Published in The Journal of biological chemistry (24.02.2017)
Published in The Journal of biological chemistry (24.02.2017)
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Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors
Kolesnikov, Alexander V., Orban, Tivadar, Jin, Hui, Brooks, Celine, Hofmann, Lukas, Dong, Zhiqian, Sokolov, Maxim, Palczewski, Krzysztof, Kefalov, Vladimir J.
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2017)
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Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration
Chen, Yu, Palczewska, Grazyna, Masuho, Ikuo, Gao, Songqi, Jin, Hui, Dong, Zhiqian, Gieser, Linn, Brooks, Matthew J, Kiser, Philip D, Kern, Timothy S, Martemyanov, Kirill A, Swaroop, Anand, Palczewski, Krzysztof
Published in Science signaling (26.07.2016)
Published in Science signaling (26.07.2016)
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Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision
Lewandowski, Dominik, Foik, Andrzej T, Smidak, Roman, Choi, Elliot H, Zhang, Jianye, Hoang, Thanh, Tworak, Aleksander, Suh, Susie, Leinonen, Henri, Dong, Zhiqian, Pinto, Antonio Fm, Tom, Emily, Luu, Jennings, Lee, Joan, Ma, Xiuli, Bieberich, Erhard, Blackshaw, Seth, Saghatelian, Alan, Lyon, David C, Skowronska-Krawczyk, Dorota, Tabaka, Marcin, Palczewski, Krzysztof
Published in JCI insight (22.02.2022)
Published in JCI insight (22.02.2022)
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An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease
Choi, Elliot H, Suh, Susie, Einstein, David E, Leinonen, Henri, Dong, Zhiqian, Rao, Sriganesh Ramachandra, Fliesler, Steven J, Blackshaw, Seth, Yu, Minzhong, Peachey, Neal S, Palczewski, Krzysztof, Kiser, Philip D
Published in JCI insight (10.05.2021)
Published in JCI insight (10.05.2021)
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Insoluble Aggregates and Protease-resistant Conformers of Prion Protein in Uninfected Human Brains
Yuan, Jue, Xiao, Xiangzhu, McGeehan, John, Dong, Zhiqian, Cali, Ignazio, Fujioka, Hisashi, Kong, Qingzhong, Kneale, Geoff, Gambetti, Pierluigi, Zou, Wen-Quan
Published in The Journal of biological chemistry (17.11.2006)
Published in The Journal of biological chemistry (17.11.2006)
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Publisher Correction: Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing
Suh, Susie, Choi, Elliot H., Leinonen, Henri, Foik, Andrzej T., Newby, Gregory A., Yeh, Wei-Hsi, Dong, Zhiqian, Kiser, Philip D., Lyon, David C., Liu, David R., Palczewski, Krzysztof
Published in Nature biomedical engineering (01.11.2020)
Published in Nature biomedical engineering (01.11.2020)
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Failure to Detect the Presence of Prions in the Uterine and Gestational Tissues from a Gravida with Creutzfeldt-Jakob Disease
Xiao, Xiangzhu, Miravalle, Leticia, Yuan, Jue, McGeehan, John, Dong, Zhiqian, Wyza, Robert, MacLennan, Gregory T, Golichowski, Alan M, Kneale, Geoff, King, Nicholas, Kong, Qingzhong, Spina, Salvatore, Vidal, Ruben, Ghetti, Bernardino, Roos, Karen, Gambetti, Pierluigi, Zou, Wen-Quan
Published in The American journal of pathology (01.05.2009)
Published in The American journal of pathology (01.05.2009)
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Creutzfeldt-Jakob Disease (CJD) with a Mutation at Codon 148 of Prion Protein Gene: Relationship with Sporadic CJD
Pastore, Manuela, Chin, Steven S, Bell, Karen L, Dong, Zhiqian, Yang, Qiwei, Yang, Lizhu, Yuan, Jue, Chen, Shu G, Gambetti, Pierluigi, Zou, Wen-Quan
Published in The American journal of pathology (01.12.2005)
Published in The American journal of pathology (01.12.2005)
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Simplified Collapse Analysis Model for RC Frames with Cyclic Deterioration Behaviors
Li, Gang, Yu, Liling, Dong, Zhiqian
Published in Journal of earthquake engineering : JEE (25.01.2022)
Published in Journal of earthquake engineering : JEE (25.01.2022)
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Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model
Luu, Jennings, Kallestad, Les, Hoang, Thanh, Lewandowski, Dominik, Dong, Zhiqian, Blackshaw, Seth, Palczewski, Krzysztof
Published in Human molecular genetics (29.08.2020)
Published in Human molecular genetics (29.08.2020)
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