The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957
Miguel-Blanco, Celia, Murithi, James M., Benavente, Ernest Diez, Angrisano, Fiona, Sala, Katarzyna A., van Schalkwyk, Donelly A., Vanaerschot, Manu, Schwach, Frank, Fuchter, Matthew J., Billker, Oliver, Sutherland, Colin J., Campino, Susana G., Clark, Taane G., Blagborough, Andrew M., Fidock, David A., Herreros, Esperanza, Gamo, Francisco Javier, Baum, Jake, Delves, Michael J.
Published in Scientific reports (21.01.2021)
Published in Scientific reports (21.01.2021)
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Journal Article
Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs
Mohring, Franziska, van Schalkwyk, Donelly A, Henrici, Ryan C, Blasco, Benjamin, Leroy, Didier, Sutherland, Colin J, Moon, Robert W
Published in mBio (26.10.2022)
Published in mBio (26.10.2022)
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Journal Article
A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections
Grignard, Lynn, Nolder, Debbie, Sepúlveda, Nuno, Berhane, Araia, Mihreteab, Selam, Kaaya, Robert, Phelan, Jody, Moser, Kara, van Schalkwyk, Donelly A., Campino, Susana, Parr, Jonathan B., Juliano, Jonathan J., Chiodini, Peter, Cunningham, Jane, Sutherland, Colin J., Drakeley, Chris, Beshir, Khalid B.
Published in EBioMedicine (01.05.2020)
Published in EBioMedicine (01.05.2020)
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Journal Article
Ex vivo susceptibility to new antimalarial agents differs among human-infecting Plasmodium species
van Schalkwyk, Donelly A., Moon, Robert W., Duffey, Maëlle, Leroy, Didier, Sutherland, Colin J.
Published in International journal for parasitology -- drugs and drug resistance (01.12.2021)
Published in International journal for parasitology -- drugs and drug resistance (01.12.2021)
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Journal Article
Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum
Tan, Angelica F, Sakam, Sitti Saimah Binti, Rajahram, Giri S, William, Timothy, Abd Rachman Isnadi, Mohammad Faruq, Daim, Sylvia, Barber, Bridget E, Kho, Steven, Sutherland, Colin J, Anstey, Nicholas M, Yerlikaya, Seda, van Schalkwyk, Donelly A, Grigg, Matthew J
Published in Frontiers in cellular and infection microbiology (17.10.2022)
Published in Frontiers in cellular and infection microbiology (17.10.2022)
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Journal Article
Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer
Abacha, Yabalu Z, Forkuo, Arnold Donkor, Gbedema, Stephen Y, Mittal, Nimisha, Ottilie, Sabine, Rocamora, Frances, Winzeler, Elizabeth A, van Schalkwyk, Donelly A, Kelly, John M, Taylor, Martin C, Reader, Janette, Birkholtz, Lyn-Marie, Lisgarten, David R, Cockcroft, Jeremy K, Lisgarten, John N, Palmer, Rex A, Talbert, Rosemary C, Shnyder, Steven D, Wright, Colin W
Published in Frontiers in pharmacology (26.04.2022)
Published in Frontiers in pharmacology (26.04.2022)
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Journal Article
Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum
van Schalkwyk, Donelly A., Blasco, Benjamin, Davina Nuñez, Rocio, Liew, Jonathan W.K., Amir, Amirah, Lau, Yee L., Leroy, Didier, Moon, Robert W., Sutherland, Colin J.
Published in International journal for parasitology -- drugs and drug resistance (01.04.2019)
Published in International journal for parasitology -- drugs and drug resistance (01.04.2019)
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Journal Article
The Inhibitory Effect of 2-Halo Derivatives of d-Glucose on Glycolysis and on the Proliferation of the Human Malaria Parasite Plasmodium falciparum
van Schalkwyk, Donelly A, Priebe, Waldemar, Saliba, Kevin J
Published in The Journal of pharmacology and experimental therapeutics (01.11.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2008)
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Journal Article
Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress
van Schalkwyk, Donelly A, Saliba, Kevin J, Biagini, Giancarlo A, Bray, Patrick G, Kirk, Kiaran
Published in PloS one (11.03.2013)
Published in PloS one (11.03.2013)
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Journal Article
Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death
van Schalkwyk, Donelly A., Chan, Xie W.A., Misiano, Paola, Gagliardi, Stefania, Farina, Carlo, Saliba, Kevin J.
Published in Biochemical pharmacology (01.05.2010)
Published in Biochemical pharmacology (01.05.2010)
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Journal Article
1H-NMR metabolite profiles of different strains of Plasmodium falciparum
Teng, Rongwei, Lehane, Adele M, Winterberg, Markus, Shafik, Sarah H, Summers, Robert L, Martin, Rowena E, van Schalkwyk, Donelly A, Junankar, Pauline R, Kirk, Kiaran
Published in Bioscience reports (21.11.2014)
Published in Bioscience reports (21.11.2014)
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Journal Article
Corrigendum to ‘A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections’
Grignard, Lynn, Nolder, Debbie, Sepulveda, Nuno, Berhane, Araia, Mihreteab, Selam, Kaaya, Robert, Phelan, Jody, Moser, Kara, van Schalkwyk, Donelly A., Campino, Susana, Parr, Jonathan B., Juliano, Jonathan J., Chiodini, Peter, Cunningham, Jane, Sutherland, Colin J., Drakeley, Chris, Beshir, Khalid B.
Published in EBioMedicine (01.03.2021)
Published in EBioMedicine (01.03.2021)
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Journal Article
Fate of haem iron in the malaria parasite Plasmodium falciparum
Egan, Timothy J, Combrinck, Jill M, Egan, Joanne, Hearne, Giovanni R, Marques, Helder M, Ntenteni, Skhumbuzo, Sewell, B Trevor, Smith, Peter J, Taylor, Dale, van Schalkwyk, Donelly A, Walden, Jason C
Published in Biochemical journal (15.07.2002)
Published in Biochemical journal (15.07.2002)
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Journal Article
Differential Drug Efflux or Accumulation Does Not Explain Variation in the Chloroquine Response of Plasmodium falciparum Strains Expressing the Same Isoform of Mutant PfCRT
Lehane, Adele M, van Schalkwyk, Donelly A, Valderramos, Stephanie G, Fidock, David A, Kirk, Kiaran
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
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Journal Article
In Vitro Antimalarial Activity of a Series of Cationic 2,2‘-Bipyridyl- and 1,10-Phenanthrolineplatinum(II) Benzoylthiourea Complexes
Egan, Timothy J, Koch, Klaus R, Swan, Paul L, Clarkson, Cailean, Van Schalkwyk, Donelly A, Smith, Peter J
Published in Journal of medicinal chemistry (20.05.2004)
Published in Journal of medicinal chemistry (20.05.2004)
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Journal Article
pfk13 -Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom
Sutherland, Colin J, Lansdell, Paul, Sanders, Mandy, Muwanguzi, Julian, van Schalkwyk, Donelly A, Kaur, Harparkash, Nolder, Debbie, Tucker, Julie, Bennett, Hayley M, Otto, Thomas D, Berriman, Matthew, Patel, Trupti A, Lynn, Roderick, Gkrania-Klotsas, Effrossyni, Chiodini, Peter L
Published in Antimicrobial agents and chemotherapy (01.03.2017)
Published in Antimicrobial agents and chemotherapy (01.03.2017)
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