Regulation of the ER stress response by a mitochondrial microprotein
Chu, Qian, Martinez, Thomas F., Novak, Sammy Weiser, Donaldson, Cynthia J., Tan, Dan, Vaughan, Joan M., Chang, Tina, Diedrich, Jolene K., Andrade, Leo, Kim, Andrew, Zhang, Tong, Manor, Uri, Saghatelian, Alan
Published in Nature communications (25.10.2019)
Published in Nature communications (25.10.2019)
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The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression
Benner, Christopher, van der Meulen, Talitha, Cacéres, Elena, Tigyi, Kristof, Donaldson, Cynthia J, Huising, Mark O
Published in BMC genomics (22.07.2014)
Published in BMC genomics (22.07.2014)
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Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion
van der Meulen, Talitha, Donaldson, Cynthia J, Cáceres, Elena, Hunter, Anna E, Cowing-Zitron, Christopher, Pound, Lynley D, Adams, Michael W, Zembrzycki, Andreas, Grove, Kevin L, Huising, Mark O
Published in Nature medicine (01.07.2015)
Published in Nature medicine (01.07.2015)
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Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets
van der Meulen, Talitha, Mawla, Alex M., DiGruccio, Michael R., Adams, Michael W., Nies, Vera, Dólleman, Sophie, Liu, Siming, Ackermann, Amanda M., Cáceres, Elena, Hunter, Anna E., Kaestner, Klaus H., Donaldson, Cynthia J., Huising, Mark O.
Published in Cell metabolism (04.04.2017)
Published in Cell metabolism (04.04.2017)
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Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses
Lee, Jennifer, Moraes-Vieira, Pedro M, Castoldi, Angela, Aryal, Pratik, Yee, Eric U, Vickers, Christopher, Parnas, Oren, Donaldson, Cynthia J, Saghatelian, Alan, Kahn, Barbara B
Published in The Journal of biological chemistry (14.10.2016)
Published in The Journal of biological chemistry (14.10.2016)
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Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets
DiGruccio, Michael R, Mawla, Alex M, Donaldson, Cynthia J, Noguchi, Glyn M, Vaughan, Joan, Cowing-Zitron, Christopher, van der Meulen, Talitha, Huising, Mark O
Published in Molecular metabolism (Germany) (01.07.2016)
Published in Molecular metabolism (Germany) (01.07.2016)
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Identification of Microprotein–Protein Interactions via APEX Tagging
Chu, Qian, Rathore, Annie, Diedrich, Jolene K, Donaldson, Cynthia J, Yates, John R, Saghatelian, Alan
Published in Biochemistry (Easton) (05.07.2017)
Published in Biochemistry (Easton) (05.07.2017)
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CRFR1 is expressed on pancreatic β cells, promotes β cell proliferation, and potentiates insulin secretion in a glucose-dependent manner
Huising, Mark O, van der Meulen, Talitha, Vaughan, Joan M, Matsumoto, Masahito, Donaldson, Cynthia J, Park, Hannah, Billestrup, Nils, Vale, Wylie W
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
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Artemether Does Not Turn α Cells into β Cells
van der Meulen, Talitha, Lee, Sharon, Noordeloos, Els, Donaldson, Cynthia J., Adams, Michael W., Noguchi, Glyn M., Mawla, Alex M., Huising, Mark O.
Published in Cell metabolism (09.01.2018)
Published in Cell metabolism (09.01.2018)
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MIEF1 Microprotein Regulates Mitochondrial Translation
Rathore, Annie, Chu, Qian, Tan, Dan, Martinez, Thomas F, Donaldson, Cynthia J, Diedrich, Jolene K, Yates, John R, Saghatelian, Alan
Published in Biochemistry (Easton) (25.09.2018)
Published in Biochemistry (Easton) (25.09.2018)
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Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis
Syed, Ismail, Lee, Jennifer, Moraes-Vieira, Pedro M., Donaldson, Cynthia J., Sontheimer, Alexandra, Aryal, Pratik, Wellenstein, Kerry, Kolar, Matthew J., Nelson, Andrew T., Siegel, Dionicio, Mokrosinski, Jacek, Farooqi, I. Sadaf, Zhao, Juan Juan, Yore, Mark M., Peroni, Odile D., Saghatelian, Alan, Kahn, Barbara B.
Published in Cell metabolism (06.02.2018)
Published in Cell metabolism (06.02.2018)
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Residues of Corticotropin Releasing Factor-binding Protein (CRF-BP) That Selectively Abrogate Binding to CRF but Not to Urocortin 1
Huising, Mark O., Vaughan, Joan M., Shah, Shaili H., Grillot, Katherine L., Donaldson, Cynthia J., Rivier, Jean, Flik, Gert, Vale, Wylie W.
Published in The Journal of biological chemistry (04.04.2008)
Published in The Journal of biological chemistry (04.04.2008)
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Biochemistry and Protein Interactions of the CYREN Microprotein
Xie, Lina, Bowman, Marianne E., Louie, Gordon V., Zhang, Cheng, Ardejani, Maziar S., Huang, Xuemei, Chu, Qian, Donaldson, Cynthia J., Vaughan, Joan M., Shan, Huanqi, Powers, Evan T., Kelly, Jeffery W., Lyumkis, Dimitry, Noel, Joseph P., Saghatelian, Alan
Published in Biochemistry (Easton) (07.11.2023)
Published in Biochemistry (Easton) (07.11.2023)
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HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective
Chu, Qian, Diedrich, Jolene K, Vaughan, Joan M, Donaldson, Cynthia J, Nunn, Michael F, Lee, Kuo-Fen, Saghatelian, Alan
Published in Journal of the American Chemical Society (03.08.2016)
Published in Journal of the American Chemical Society (03.08.2016)
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AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice
Erikci Ertunc, Meric, Kok, Bernard P., Parsons, William H., Wang, Justin G., Tan, Dan, Donaldson, Cynthia J., Pinto, Antonio F.M., Vaughan, Joan M., Ngo, Nhi, Lum, Kenneth M., Henry, Cassandra L., Coppola, Aundrea R., Niphakis, Micah J., Cravatt, Benjamin F., Saez, Enrique, Saghatelian, Alan
Published in The Journal of biological chemistry (01.05.2020)
Published in The Journal of biological chemistry (01.05.2020)
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A class of anti-inflammatory lipids decrease with aging in the central nervous system
Tan, Dan, Konduri, Srihari, Erikci Ertunc, Meric, Zhang, Pan, Wang, Justin, Chang, Tina, Pinto, Antonio F. M., Rocha, Andrea, Donaldson, Cynthia J., Vaughan, Joan M., Ludwig, Raissa G., Willey, Elizabeth, Iyer, Manasi, Gray, Peter C., Maher, Pamela, Allen, Nicola J., Zuchero, J. Bradley, Dillin, Andrew, Mori, Marcelo A., Kohama, Steven G., Siegel, Dionicio, Saghatelian, Alan
Published in Nature chemical biology (01.02.2023)
Published in Nature chemical biology (01.02.2023)
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Cocaine- and Amphetamine-Regulated Transcript Is Localized in Pituitary Lactotropes and Is Regulated during Lactation
Smith, Sean M, Vaughan, Joan M, Donaldson, Cynthia J, Fernandez, Rosette E, Li, Chien, Chen, Alon, Vale, Wylie W
Published in Endocrinology (Philadelphia) (01.03.2006)
Published in Endocrinology (Philadelphia) (01.03.2006)
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Data-Driven Synthesis of Proteolysis-Resistant Peptide Hormones
Prothiwa, Michaela, Syed, Ismail, Huising, Mark O, van der Meulen, Talitha, Donaldson, Cynthia J, Trauger, Sunia A, Kahn, Barbara B, Saghatelian, Alan
Published in Journal of the American Chemical Society (24.12.2014)
Published in Journal of the American Chemical Society (24.12.2014)
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Characterization of a Pachymedusa dacnicolor-Sauvagine analog as a new high-affinity radioligand for corticotropin-releasing factor receptor studies
Perrin, Marilyn H, Tan, Laura A, Vaughan, Joan M, Lewis, Kathy A, Donaldson, Cynthia J, Miller, Charleen, Erchegyi, Judit, Rivier, Jean E, Sawchenko, Paul E
Published in The Journal of pharmacology and experimental therapeutics (01.05.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2015)
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