Multicenter, randomized, double-blind, active comparator and placebo-controlled trial of a corticotropin-releasing factor receptor-1 antagonist in generalized anxiety disorder
Coric, Vladimir, Feldman, Howard H., Oren, Dan A., Shekhar, Anantha, Pultz, Joseph, Dockens, Randy C., Wu, Xiaoling, Gentile, Kimberly A., Huang, Shu-Pang, Emison, Eileen, Delmonte, Terrye, D'Souza, Bernadette B., Zimbroff, Daniel L., Grebb, Jack A., Goddard, Andrew W., Stock, Elyse G.
Published in Depression and anxiety (01.05.2010)
Published in Depression and anxiety (01.05.2010)
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Journal Article
Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study of the Oral γ-Secretase Inhibitor BMS-708163 (Avagacestat): Tolerability Profile, Pharmacokinetic Parameters, and Pharmacodynamic Markers
Tong, Gary, MD, PhD, Wang, Jun-Sheng, PhD, Sverdlov, Oleksandr, PhD, Huang, Shu-Pang, PhD, Slemmon, Randy, PhD, Croop, Robert, MD, Castaneda, Lorna, MS, Gu, Huidong, MS, Wong, Oi, BS, Li, Hewei, MD, PhD, Berman, Robert M., MD, Smith, Christina, DPhil, Albright, Charles F., PhD, Dockens, Randy C., PhD
Published in Clinical therapeutics (01.03.2012)
Published in Clinical therapeutics (01.03.2012)
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Journal Article
6-Hydroxybuspirone Is a Major Active Metabolite of Buspirone: Assessment of Pharmacokinetics and 5-Hydroxytryptamine1A Receptor Occupancy in Rats
WONG, Harvey, DOCKENS, Randy C, PAJOR, Lori, YEOLA, Suresh, GRACE, James E, STARK, Arlene D, TAUB, Rebecca A, YOCCA, Frank D, ZACZEK, Robert C, LI, Yu-Wen
Published in Drug metabolism and disposition (01.08.2007)
Published in Drug metabolism and disposition (01.08.2007)
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Journal Article
Disposition and Metabolism of [14C]Brasofensine in Rats, Monkeys, and Humans
Zhu, Mingshe, Whigan, Daisy B, Chang, Shu Y, Dockens, Randy C
Published in Drug metabolism and disposition (01.01.2008)
Published in Drug metabolism and disposition (01.01.2008)
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Journal Article
Pre-absorption physicochemical compatibility assessment of 8-drug metabolic cocktail
Tye, Ching Kim, Wang, Zhanbin, Dockens, Randy C., Vakkalagadda, Blisse, Wang, Chunlei, Zhang, Yingru, Su, Ching Chiang, Hageman, Michael J.
Published in International journal of pharmaceutics (05.12.2016)
Published in International journal of pharmaceutics (05.12.2016)
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Journal Article
Pharmacodynamics of selective inhibition of γ-secretase by avagacestat
Albright, Charles F, Dockens, Randy C, Meredith, Jr, Jere E, Olson, Richard E, Slemmon, Randy, Lentz, Kimberley A, Wang, Jun-Sheng, Denton, R Rex, Pilcher, Gary, Rhyne, Paul W, Raybon, Joseph J, Barten, Donna M, Burton, Catherine, Toyn, Jeremy H, Sankaranarayanan, Sethu, Polson, Craig, Guss, Valerie, White, Randy, Simutis, Frank, Sanderson, Thomas, Gillman, Kevin W, Starrett, Jr, John E, Bronson, Joanne, Sverdlov, Oleksandr, Huang, Shu-Pang, Castaneda, Lorna, Feldman, Howard, Coric, Vlad, Zaczek, Robert, Macor, John E, Houston, John, Berman, Robert M, Tong, Gary
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
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Journal Article
In vitro and in vivo metabolism and pharmacokinetics of BMS-562086, a potent and orally bioavailable corticotropin-releasing factor-1 receptor antagonist
Zhou, Lian, Dockens, Randy C, Liu-Kreyche, Peggy, Grossman, Scott J, Iyer, Ramaswamy A
Published in Drug metabolism and disposition (01.06.2012)
Published in Drug metabolism and disposition (01.06.2012)
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Journal Article
Effects of Single Doses of Avagacestat (BMS-708163) on Cerebrospinal Fluid Aβ Levels in Healthy Young Men
Tong, Gary, Castaneda, Lorna, Wang, Jun-Sheng, Sverdlov, Oleksandr, Huang, Shu-Pang, Slemmon, Randy, Gu, Huidong, Wong, Oi, Li, Hewei, Berman, Robert M., Smith, Christina, Albright, Charles, Dockens, Randy C.
Published in Clinical drug investigation (01.11.2012)
Published in Clinical drug investigation (01.11.2012)
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Journal Article
Development of oral extended release formulations of 6-hydroxybuspirone
Nicholson, Sarah J., Timmins, Peter, Dockens, Randy C., Connor, Alyson, Croop, Robert, Ferrie, Peter, Zeng, Jianing, Dennis, Andrew B., Wilding, Ian
Published in Biopharmaceutics & drug disposition (01.12.2012)
Published in Biopharmaceutics & drug disposition (01.12.2012)
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Journal Article
Pharmacokinetics of a newly identified active metabolite of buspirone after administration of buspirone over its therapeutic dose range
Dockens, Randy C, Salazar, Daniel E, Fulmor, I Edgar, Wehling, Michele, Arnold, Mark E, Croop, Robert
Published in Journal of clinical pharmacology (01.11.2006)
Published in Journal of clinical pharmacology (01.11.2006)
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Journal Article
Brasofensine treatment for Parkinson's disease in combination with levodopa/carbidopa
Frackiewicz, Edyta J, Jhee, Stanford S, Shiovitz, Thomas M, Webster, Jonathan, Topham, Christine, Dockens, Randy C, Whigan, Daisy, Salazar, Daniel E, Cutler, Neal R
Published in The Annals of pharmacotherapy (01.02.2002)
Published in The Annals of pharmacotherapy (01.02.2002)
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Journal Article
Comparison of pharmacokinetics of Lanoteplase and alteplase during acute myocardial infarction
KOSTIS, John B, DOCKERS, Randy C, WEN CHYI SHYU, LIAO, Wei-Chi, THADANI, Udho, BETHALA, Vasnath, PEPINE, Carl, LEIMBACH, Wayne, VACHHARAJANI, Nimish, RAYMOND, Ralph H, STOUFFER, Bruce C, TAY, Lee K
Published in Clinical pharmacokinetics (2002)
Published in Clinical pharmacokinetics (2002)
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Journal Article
Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study of the Oral [gamma]-Secretase Inhibitor BMS-708163 (Avagacestat): Tolerability Profile, Pharmacokinetic Parameters, and Pharmacodynamic Markers
Tong, Gary, Wang, Jun-Sheng, Sverdlov, Oleksandr, Huang, Shu-Pang, Slemmon, Randy, Croop, Robert, Castaneda, Lorna, Gu, Huidong, Wong, Oi, Li, Hewei, Berman, Robert M, Smith, Christina, Albright, Charles F, Dockens, Randy C
Published in Clinical therapeutics (01.03.2012)
Published in Clinical therapeutics (01.03.2012)
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Journal Article
Anticonvulsant activity of some 4-aminobenzamides
Clark, C. Randall, Wells, Martha J. M, Sansom, Ricky T, Norris, George N, Dockens, Randy C, Ravis, William R
Published in Journal of medicinal chemistry (01.06.1984)
Published in Journal of medicinal chemistry (01.06.1984)
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Journal Article
Effects of Single Doses of Avagacestat (BMS-708163) on Cerebrospinal Fluid Aß Levels in Healthy Young Men
Tong, Gary, Castaneda, Lorna, Wang, Jun-Sheng, Sverdlov, Oleksandr, Huang, Shu-Pang, Slemmon, Randy, Gu, Huidong, Wong, Oi, Li, Hewei, Berman, Robert M, Smith, Christina, Albright, Charles, Dockens, Randy C
Published in Clinical drug investigation (01.11.2012)
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Published in Clinical drug investigation (01.11.2012)
Journal Article
6-Hydroxybuspirone Is a Major Active Metabolite of Buspirone: Assessment of Pharmacokinetics and 5-Hydroxytryptamine sub(1A) Receptor Occupancy in Rats
Wong, Harvey, Dockens, Randy C, Pajor, Lori, Yeola, Suresh, Grace, James EJr, Stark, Arlene D, Taub, Rebecca A, Yocca, Frank D, Zaczek, Robert C, Li, Yu-Wen
Published in Drug metabolism and disposition (01.08.2007)
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Published in Drug metabolism and disposition (01.08.2007)
Journal Article
6-Hydroxybuspirone Is a Major Active Metabolite of Buspirone: Assessment of Pharmacokinetics and 5-Hydroxytryptamine 1A Receptor Occupancy in Rats
Wong, Harvey, Dockens, Randy C., Pajor, Lori, Yeola, Suresh, Grace, James E., Stark, Arlene D., Taub, Rebecca A., Yocca, Frank D., Zaczek, Robert C., Li, Yu-Wen
Published in Drug metabolism and disposition (01.08.2007)
Published in Drug metabolism and disposition (01.08.2007)
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Journal Article
Disposition of Radiolabeled Ifetroban in Rats, Dogs, Monkeys, and Humans
DOCKENS, R. C, SANTONE, K. S, MITROKA, J. G, MORRISON, R. A, JEMAL, M, GREENE, D. S, BARBHAIYA, R. H
Published in Drug metabolism and disposition (01.08.2000)
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Published in Drug metabolism and disposition (01.08.2000)
Journal Article