ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23
Blobel, Carl P, Weskamp, Gisela, Ford, Jill W, Sturgill, Jamie, Martin, Steve, Docherty, Andrew J P, Swendeman, Steven, Broadway, Neil, Hartmann, Dieter, Saftig, Paul, Umland, Shelby, Sehara-Fujisawa, Atsuko, Black, Roy A, Ludwig, Andreas, Becherer, J David, Conrad, Daniel H
Published in Nature Immunology (01.12.2006)
Published in Nature Immunology (01.12.2006)
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Journal Article
The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A
Willenbrock, Frances, Crabbe, Thomas, Slocombe, Patrick M, Sutton, Chris W, Docherty, Andrew J. P, Cockett, Mark I, O'Shea, Mark, Brocklehurst, Keith, Phillips, Ian R, Murphy, Gillian
Published in Biochemistry (Easton) (27.04.1993)
Published in Biochemistry (Easton) (27.04.1993)
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Journal Article
The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity
Murphy, Gillian, Houbrechts, Annick, Cockett, Mark I, Williamson, Richard A, O'Shea, Mark, Docherty, Andrew J. P
Published in Biochemistry (Easton) (01.08.1991)
Published in Biochemistry (Easton) (01.08.1991)
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Journal Article
Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family
Williamson, Richard A, Martorell, Gabriel, Carr, Mark D, Murphy, Gillian, Docherty, Andrew J. P, Freedman, Robert B, Feeney, James
Published in Biochemistry (Easton) (04.10.1994)
Published in Biochemistry (Easton) (04.10.1994)
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Journal Article
Different Domain Interactions Are Involved in the Binding of Tissue Inhibitors of Metalloproteinases to Stromelysin-1 and Gelatinase A
Nguyen, Quang, Willenbrock, Frances, Cockett, Mark I, O'Shea, Mark, Docherty, Andrew J. P, Murphy, Gillian
Published in Biochemistry (Easton) (01.03.1994)
Published in Biochemistry (Easton) (01.03.1994)
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Journal Article
Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity
Docherty, A J, Lyons, A, Smith, B J, Wright, E M, Stephens, P E, Harris, T J, Murphy, G, Reynolds, J J
Published in Nature (London) (01.11.1985)
Published in Nature (London) (01.11.1985)
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Journal Article
Biochemical characterization of matrilysin. Activation conforms to the stepwise mechanisms proposed for other matrix metalloproteinases
Crabbe, Thomas, Willenbrock, Frances, Eaton, Di, Hynds, Peter, Carne, Alexander F, Murphy, Gillian, Docherty, Andrew J. P
Published in Biochemistry (Easton) (01.09.1992)
Published in Biochemistry (Easton) (01.09.1992)
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Journal Article
Active gelatinase B is identified by histozymography in the cartilage resorption sites of developing long bones
Lee, Eunice R., Murphy, Gillian, El‐Alfy, Mohamed, Davoli, Maria Antonietta, Lamplugh, Lisa, Docherty, Andrew J., Leblond, Charles Philippe
Published in Developmental dynamics (01.07.1999)
Published in Developmental dynamics (01.07.1999)
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Journal Article
The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts
Hill, P A, Murphy, G, Docherty, A J, Hembry, R M, Millican, T A, Reynolds, J J, Meikle, M C
Published in Journal of cell science (01.11.1994)
Published in Journal of cell science (01.11.1994)
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Journal Article
Mutation of the Active Site Glutamic Acid of Human Gelatinase A: Effects on Latency, Catalysis, and the Binding of Tissue Inhibitor of Metalloproteinases-1
Crabbe, Thomas, Zucker, Stanley, Cockett, Mark I, Willenbrock, Frances, Tickle, Simon, O'Connell, James P, Scothern, Janeen M, Murphy, Gillian, Docherty, Andrew J. P
Published in Biochemistry (Easton) (01.05.1994)
Published in Biochemistry (Easton) (01.05.1994)
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Journal Article
Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13
O'Shea, Mark, Willenbrock, Frances, Williamson, Richard A, Cockett, Mark I, Freedman, Robert B, Reynolds, John J, Docherty, Andrew J. P, Murphy, Gillian
Published in Biochemistry (Easton) (27.10.1992)
Published in Biochemistry (Easton) (27.10.1992)
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Journal Article
Meltrin γ (ADAM-9) mediates cellular adhesion through α6β1 integrin, leading to a marked induction of fibroblast cell motility
Nath, Deepa, Slocombe, Patrick M., Webster, Ailsa, Stephens, Paul E., Docherty, Andrew J. P., Murphy, Gillian
Published in Journal of cell science (15.06.2000)
Published in Journal of cell science (15.06.2000)
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Journal Article
The metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesion
Schlomann, Uwe, Wildeboer, Dirk, Webster, Ailsa, Antropova, Olga, Zeuschner, Dagmar, Knight, C Graham, Docherty, Andrew J P, Lambert, Marc, Skelton, Lisa, Jockusch, Harald, Bartsch, Jörg W
Published in The Journal of biological chemistry (13.12.2002)
Published in The Journal of biological chemistry (13.12.2002)
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Journal Article
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs
Amour, Augustin, Knight, C.Graham, English, William R, Webster, Ailsa, Slocombe, Patrick M, Knäuper, Vera, Docherty, Andrew J.P, Becherer, J.David, Blobel, Carl P, Murphy, Gillian
Published in FEBS letters (31.07.2002)
Published in FEBS letters (31.07.2002)
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Journal Article
Dissecting the role of matrix metalloproteinases (MMP) and integrin αvβ3 in angiogenesis in vitro : Absence of hemopexin C domain bioactivity, but membrane-type 1-MMP and αvβ3 are critical
NISATO, Riccardo E, HOSSEINI, Ghamartaj, PEPPER, Michael S, SIRRENBERG, Christian, BUTLER, Georgina S, CRABBE, Thomas, DOCHERTY, Andrew J. P, WIESNER, Matthias, MURPHY, Gillian, OVERALL, Christopher M, GOODMAN, Simon L
Published in Cancer research (Chicago, Ill.) (15.10.2005)
Published in Cancer research (Chicago, Ill.) (15.10.2005)
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Journal Article
The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitor activity [Erratum to document cited in CA115(9):88133x]
Murphy, Gillian, Houbrechts, Annick, Cockett, Mark I, Williamson, Richard A, O'Shea, Mark, Docherty, Andrew J. P
Published in Biochemistry (Easton) (01.10.1991)
Published in Biochemistry (Easton) (01.10.1991)
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Journal Article
The matrix metalloproteinases and their inhibitors
Murphy, G, Docherty, A J
Published in American journal of respiratory cell and molecular biology (01.08.1992)
Published in American journal of respiratory cell and molecular biology (01.08.1992)
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Journal Article
Dissecting the role of matrix metalloproteinases (MMP) and integrin alpha(v)beta3 in angiogenesis in vitro: absence of hemopexin C domain bioactivity, but membrane-Type 1-MMP and alpha(v)beta3 are critical
Nisato, Riccardo E, Hosseini, Ghamartaj, Sirrenberg, Christian, Butler, Georgina S, Crabbe, Thomas, Docherty, Andrew J P, Wiesner, Matthias, Murphy, Gillian, Overall, Christopher M, Goodman, Simon L, Pepper, Michael S
Published in Cancer research (Chicago, Ill.) (15.10.2005)
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Published in Cancer research (Chicago, Ill.) (15.10.2005)
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