Structural and dynamic requirements for optimal activity of the essential bacterial enzyme dihydrodipicolinate synthase
Reboul, C F, Porebski, B T, Griffin, M D W, Dobson, R C J, Perugini, M A, Gerrard, J A, Buckle, A M
Published in PLoS computational biology (01.06.2012)
Published in PLoS computational biology (01.06.2012)
Get full text
Journal Article
Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis
Domigan, L.J., Scally, S.W., Fogg, M.J., Hutton, C.A., Perugini, M.A., Dobson, R.C.J., Muscroft-Taylor, A.C., Gerrard, J.A., Devenish, S.R.A.
Published in Biochimica et biophysica acta (01.10.2009)
Published in Biochimica et biophysica acta (01.10.2009)
Get full text
Journal Article
Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
Horne, Christopher R., Venugopal, Hariprasad, Panjikar, Santosh, Wood, David M., Henrickson, Amy, Brookes, Emre, North, Rachel A., Murphy, James M., Friemann, Rosmarie, Griffin, Michael D. W., Ramm, Georg, Demeler, Borries, Dobson, Renwick C. J.
Published in Nature communications (31.03.2021)
Published in Nature communications (31.03.2021)
Get full text
Journal Article
N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization
Currie, Michael J., Manjunath, Lavanyaa, Horne, Christopher R., Rendle, Phillip M., Subramanian, Ramaswamy, Friemann, Rosmarie, Fairbanks, Antony J., Muscroft-Taylor, Andrew C., North, Rachel A., Dobson, Renwick C.J.
Published in The Journal of biological chemistry (01.10.2021)
Published in The Journal of biological chemistry (01.10.2021)
Get full text
Journal Article
The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
Coombes, David, Davies, James S., Newton-Vesty, Michael C., Horne, Christopher R., Setty, Thanuja G., Subramanian, Ramaswamy, Moir, James W.B., Friemann, Rosmarie, Panjikar, Santosh, Griffin, Michael D.W., North, Rachel A., Dobson, Renwick C.J.
Published in The Journal of biological chemistry (06.03.2020)
Published in The Journal of biological chemistry (06.03.2020)
Get full text
Journal Article
Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth
Bozzola, Tiago, Scalise, Mariafrancesca, Larsson, Christer U., Newton-Vesty, Michael C., Rovegno, Caterina, Mitra, Ankita, Cramer, Jonathan, Wahlgren, Weixiao Yuan, Radhakrishnan Santhakumari, Partha, Johnsson, Richard E., Schwardt, Oliver, Ernst, Beat, Friemann, Rosmarie, Dobson, Renwick C. J., Indiveri, Cesare, Schelin, Jenny, Nilsson, Ulf J., Ellervik, Ulf
Published in ACS chemical biology (15.07.2022)
Published in ACS chemical biology (15.07.2022)
Get full text
Journal Article