A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
Sharma, Amitabh, Menche, Jörg, Huang, C Chris, Ort, Tatiana, Zhou, Xiaobo, Kitsak, Maksim, Sahni, Nidhi, Thibault, Derek, Voung, Linh, Guo, Feng, Ghiassian, Susan Dina, Gulbahce, Natali, Baribaud, Frédéric, Tocker, Joel, Dobrin, Radu, Barnathan, Elliot, Liu, Hao, Panettieri, Jr, Reynold A, Tantisira, Kelan G, Qiu, Weiliang, Raby, Benjamin A, Silverman, Edwin K, Vidal, Marc, Weiss, Scott T, Barabási, Albert-László
Published in Human molecular genetics (01.06.2015)
Published in Human molecular genetics (01.06.2015)
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Journal Article
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
Greenawalt, Danielle M, Dobrin, Radu, Chudin, Eugene, Hatoum, Ida J, Suver, Christine, Beaulaurier, John, Zhang, Bin, Castro, Victor, Zhu, Jun, Sieberts, Solveig K, Wang, Susanna, Molony, Cliona, Heymsfield, Steven B, Kemp, Daniel M, Reitman, Marc L, Lum, Pek Yee, Schadt, Eric E, Kaplan, Lee M
Published in Genome research (01.07.2011)
Published in Genome research (01.07.2011)
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Journal Article
High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors
Di Narzo, Antonio F, Telesco, Shannon E, Brodmerkel, Carrie, Argmann, Carmen, Peters, Lauren A, Li, Katherine, Kidd, Brian, Dudley, Joel, Cho, Judy, Schadt, Eric E, Kasarskis, Andrew, Dobrin, Radu, Hao, Ke
Published in PLoS genetics (27.01.2017)
Published in PLoS genetics (27.01.2017)
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Journal Article
The Arrestin Domain-Containing 3 Protein Regulates Body Mass and Energy Expenditure
Patwari, Parth, Emilsson, Valur, Schadt, Eric E., Chutkow, William A., Lee, Samuel, Marsili, Alessandro, Zhang, Yongzhao, Dobrin, Radu, Cohen, David E., Larsen, P. Reed, Zavacki, Ann Marie, Fong, Loren G., Young, Stephen G., Lee, Richard T.
Published in Cell metabolism (02.11.2011)
Published in Cell metabolism (02.11.2011)
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Journal Article
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes
Zhong, Hua, Beaulaurier, John, Lum, Pek Yee, Molony, Cliona, Yang, Xia, Macneil, Douglas J, Weingarth, Drew T, Zhang, Bin, Greenawalt, Danielle, Dobrin, Radu, Hao, Ke, Woo, Sangsoon, Fabre-Suver, Christine, Qian, Su, Tota, Michael R, Keller, Mark P, Kendziorski, Christina M, Yandell, Brian S, Castro, Victor, Attie, Alan D, Kaplan, Lee M, Schadt, Eric E
Published in PLoS genetics (06.05.2010)
Published in PLoS genetics (06.05.2010)
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Journal Article
High-Throughput Identification of the Plasma Proteomic Signature of Inflammatory Bowel Disease
Di Narzo, Antonio F, Brodmerkel, Carrie, Telesco, Shannon E, Argmann, Carmen, Peters, Lauren A, Li, Katherine, Kidd, Brian, Dudley, Joel, Cho, Judy, Schadt, Eric E, Kasarskis, Andrew, Dobrin, Radu, Hao, Ke
Published in Journal of Crohn's and colitis (30.03.2019)
Published in Journal of Crohn's and colitis (30.03.2019)
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Journal Article
Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs
Zhang, Xiaoling, Gierman, Hinco J, Levy, Daniel, Plump, Andrew, Dobrin, Radu, Goring, Harald H H, Curran, Joanne E, Johnson, Matthew P, Blangero, John, Kim, Stuart K, O'Donnell, Christopher J, Emilsson, Valur, Johnson, Andrew D
Published in BMC genomics (27.06.2014)
Published in BMC genomics (27.06.2014)
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Journal Article
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network
Dobrin, Radu, Beg, Qasim K, Barabási, Albert-László, Oltvai, Zoltán N
Published in BMC bioinformatics (30.01.2004)
Published in BMC bioinformatics (30.01.2004)
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Journal Article
A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients
Peters, Lauren A, Friedman, Joshua R, Stojmirovic, Aleksandar, Hagen, Jacob, Houten, Sander, Dodatko, Tetyana, Amaro, Mariana P, Restrepo, Paula, Chai, Zhi, Rodrigo Mora, J, Raymond, Holly A, Curran, Mark, Dobrin, Radu, Das, Anuk, Xiong, Huabao, Schadt, Eric E, Argmann, Carmen, Losic, Bojan
Published in Communications biology (24.01.2023)
Published in Communications biology (24.01.2023)
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Journal Article
Dissecting cis regulation of gene expression in human metabolic tissues
Dobrin, Radu, Greenawalt, Danielle M, Hu, Guanghui, Kemp, Daniel M, Kaplan, Lee M, Schadt, Eric E, Emilsson, Valur
Published in PloS one (31.08.2011)
Published in PloS one (31.08.2011)
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Journal Article
Ppargamma2 is a key driver of longevity in the mouse
Argmann, Carmen, Dobrin, Radu, Heikkinen, Sami, Auburtin, Aurélie, Pouilly, Laurent, Cock, Terrie-Anne, Koutnikova, Hana, Zhu, Jun, Schadt, Eric E, Auwerx, Johan
Published in PLoS genetics (01.12.2009)
Published in PLoS genetics (01.12.2009)
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Journal Article
A Comparison of Partitioning Strategies for Fixed Points Based Limited Preemptive Scheduling
Markovic, Filip, Carlson, Jan, Dobrin, Radu
Published in IEEE transactions on industrial informatics (01.02.2019)
Published in IEEE transactions on industrial informatics (01.02.2019)
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Journal Article
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
Zhang, Bin, Gaiteri, Chris, Bodea, Liviu-Gabriel, Wang, Zhi, McElwee, Joshua, Podtelezhnikov, Alexei A., Zhang, Chunsheng, Xie, Tao, Tran, Linh, Dobrin, Radu, Fluder, Eugene, Clurman, Bruce, Melquist, Stacey, Narayanan, Manikandan, Suver, Christine, Shah, Hardik, Mahajan, Milind, Gillis, Tammy, Mysore, Jayalakshmi, MacDonald, Marcy E., Lamb, John R., Bennett, David A., Molony, Cliona, Stone, David J., Gudnason, Vilmundur, Myers, Amanda J., Schadt, Eric E., Neumann, Harald, Zhu, Jun, Emilsson, Valur
Published in Cell (25.04.2013)
Published in Cell (25.04.2013)
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Journal Article
A functional genomics predictive network model identifies regulators of inflammatory bowel disease
Peters, Lauren A, Perrigoue, Jacqueline, Mortha, Arthur, Iuga, Alina, Song, Won-Min, Neiman, Eric M, Llewellyn, Sean R, Di Narzo, Antonio, Kidd, Brian A, Telesco, Shannon E, Zhao, Yongzhong, Stojmirovic, Aleksandar, Sendecki, Jocelyn, Shameer, Khader, Miotto, Riccardo, Losic, Bojan, Shah, Hardik, Lee, Eunjee, Wang, Minghui, Faith, Jeremiah J, Kasarskis, Andrew, Brodmerkel, Carrie, Curran, Mark, Das, Anuk, Friedman, Joshua R, Fukui, Yoshinori, Humphrey, Mary Beth, Iritani, Brian M, Sibinga, Nicholas, Tarrant, Teresa K, Argmann, Carmen, Hao, Ke, Roussos, Panos, Zhu, Jun, Zhang, Bin, Dobrin, Radu, Mayer, Lloyd F, Schadt, Eric E
Published in Nature genetics (01.10.2017)
Published in Nature genetics (01.10.2017)
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Journal Article
Dissecting self-renewal in stem cells with RNA interference
Ivanova, Natalia, Lemischka, Ihor R, Dobrin, Radu, Lu, Rong, Kotenko, Iulia, Levorse, John, DeCoste, Christina, Schafer, Xenia, Lun, Yi
Published in Nature (03.08.2006)
Published in Nature (03.08.2006)
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Journal Article
NDEx, the Network Data Exchange
Pratt, Dexter, Chen, Jing, Welker, David, Rivas, Ricardo, Pillich, Rudolf, Rynkov, Vladimir, Ono, Keiichiro, Miello, Carol, Hicks, Lyndon, Szalma, Sandor, Stojmirovic, Aleksandar, Dobrin, Radu, Braxenthaler, Michael, Kuentzer, Jan, Demchak, Barry, Ideker, Trey
Published in Cell systems (28.10.2015)
Published in Cell systems (28.10.2015)
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Journal Article
Cache-aware response time analysis for real-time tasks with fixed preemption points
Markovic, Filip, Carlson, Jan, Dobrin, Radu
Published in 2020 IEEE Real-Time and Embedded Technology and Applications Symposium (RTAS) (01.04.2020)
Published in 2020 IEEE Real-Time and Embedded Technology and Applications Symposium (RTAS) (01.04.2020)
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