TP53 gain-of-function mutation promotes inflammation in glioblastoma
Ham, Seok Won, Jeon, Hee-Young, Jin, Xiong, Kim, Eun-Jung, Kim, Jun-Kyum, Shin, Yong Jae, Lee, Yeri, Kim, Se Hoon, Lee, Seon Yong, Seo, Sunyoung, Park, Min Gi, Kim, Hye-Mi, Nam, Do-Hyun, Kim, Hyunggee
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Published in Cell death and differentiation (01.03.2019)
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MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
Oldrini, Barbara, Vaquero-Siguero, Nuria, Mu, Quanhua, Kroon, Paula, Zhang, Ying, Galán-Ganga, Marcos, Bao, Zhaoshi, Wang, Zheng, Liu, Hanjie, Sa, Jason K., Zhao, Junfei, Kim, Hoon, Rodriguez-Perales, Sandra, Nam, Do-Hyun, Verhaak, Roel G. W., Rabadan, Raul, Jiang, Tao, Wang, Jiguang, Squatrito, Massimo
Published in Nature communications (04.08.2020)
Published in Nature communications (04.08.2020)
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Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma
Kim, Kyu-Tae, Lee, Hye Won, Lee, Hae-Ock, Song, Hye Jin, Jeong, Da Eun, Shin, Sang, Kim, Hyunho, Shin, Yoojin, Nam, Do-Hyun, Jeong, Byong Chang, Kirsch, David G, Joo, Kyeung Min, Park, Woong-Yang
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Published in Genome Biology (29.04.2016)
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ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages
Yin, Jinlong, Kim, Sung Soo, Choi, Eunji, Oh, Young Taek, Lin, Weiwei, Kim, Tae-Hoon, Sa, Jason K, Hong, Jun Hee, Park, Se Hwan, Kwon, Hyung Joon, Jin, Xiong, You, Yeonhee, Kim, Ji Hye, Kim, Hyunggee, Son, Jaekyoung, Lee, Jeongwu, Nam, Do-Hyun, Choi, Kui Son, Shi, Bingyang, Gwak, Ho-Shin, Yoo, Heon, Iavarone, Antonio, Kim, Jong Heon, Park, Jong Bae
Published in Nature communications (12.06.2020)
Published in Nature communications (12.06.2020)
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Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient
Lee, Hye Won, Chung, Woosung, Lee, Hae-Ock, Jeong, Da Eun, Jo, Areum, Lim, Joung Eun, Hong, Jeong Hee, Nam, Do-Hyun, Jeong, Byong Chang, Park, Se Hoon, Joo, Kyeung-Min, Park, Woong-Yang
Published in Genome medicine (27.05.2020)
Published in Genome medicine (27.05.2020)
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Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy
Bastola, Soniya, Pavlyukov, Marat S., Yamashita, Daisuke, Ghosh, Sadashib, Cho, Heejin, Kagaya, Noritaka, Zhang, Zhuo, Minata, Mutsuko, Lee, Yeri, Sadahiro, Hirokazu, Yamaguchi, Shinobu, Komarova, Svetlana, Yang, Eddy, Markert, James, Nabors, Louis B., Bhat, Krishna, Lee, James, Chen, Qin, Crossman, David K., Shin-Ya, Kazuo, Nam, Do-Hyun, Nakano, Ichiro
Published in Nature communications (16.09.2020)
Published in Nature communications (16.09.2020)
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Clonal evolution of glioblastoma under therapy
Wang, Jiguang, Cazzato, Emanuela, Ladewig, Erik, Frattini, Veronique, Rosenbloom, Daniel I S, Zairis, Sakellarios, Abate, Francesco, Liu, Zhaoqi, Elliott, Oliver, Shin, Yong-Jae, Lee, Jin-Ku, Lee, In-Hee, Park, Woong-Yang, Eoli, Marica, Blumberg, Andrew J, Lasorella, Anna, Nam, Do-Hyun, Finocchiaro, Gaetano, Iavarone, Antonio, Rabadan, Raul
Published in Nature genetics (01.07.2016)
Published in Nature genetics (01.07.2016)
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Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells
Kim, Kyu-Tae, Lee, Hye Won, Lee, Hae-Ock, Kim, Sang Cheol, Seo, Yun Jee, Chung, Woosung, Eum, Hye Hyeon, Nam, Do-Hyun, Kim, Junhyong, Joo, Kyeung Min, Park, Woong-Yang
Published in Genome Biology (19.06.2015)
Published in Genome Biology (19.06.2015)
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Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor
Hu, Huimin, Mu, Quanhua, Bao, Zhaoshi, Chen, Yiyun, Liu, Yanwei, Chen, Jing, Wang, Kuanyu, Wang, Zheng, Nam, Yoonhee, Jiang, Biaobin, Sa, Jason K., Cho, Hee-Jin, Her, Nam-Gu, Zhang, Chuanbao, Zhao, Zheng, Zhang, Ying, Zeng, Fan, Wu, Fan, Kang, Xun, Liu, Yuqing, Qian, Zenghui, Wang, Zhiliang, Huang, Ruoyu, Wang, Qiangwei, Zhang, Wei, Qiu, Xiaoguang, Li, Wenbin, Nam, Do-Hyun, Fan, Xiaolong, Wang, Jiguang, Jiang, Tao
Published in Cell (29.11.2018)
Published in Cell (29.11.2018)
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Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma
deCarvalho, Ana C, Kim, Hoon, Poisson, Laila M, Winn, Mary E, Mueller, Claudius, Cherba, David, Koeman, Julie, Seth, Sahil, Protopopov, Alexei, Felicella, Michelle, Zheng, Siyuan, Multani, Asha, Jiang, Yongying, Zhang, Jianhua, Nam, Do-Hyun, Petricoin, Emanuel F, Chin, Lynda, Mikkelsen, Tom, Verhaak, Roel G W
Published in Nature genetics (01.05.2018)
Published in Nature genetics (01.05.2018)
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SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma
Son, Myung Jin, Woolard, Kevin, Nam, Do-Hyun, Lee, Jeongwu, Fine, Howard A.
Published in Cell stem cell (08.05.2009)
Published in Cell stem cell (08.05.2009)
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Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
Kim, Eunhee, Kim, Misuk, Woo, Dong-Hun, Shin, Yongjae, Shin, Jihye, Chang, Nakho, Oh, Young Taek, Kim, Hong, Rheey, Jingeun, Nakano, Ichiro, Lee, Cheolju, Joo, Kyeung Min, Rich, Jeremy N., Nam, Do-Hyun, Lee, Jeongwu
Published in Cancer cell (10.06.2013)
Published in Cancer cell (10.06.2013)
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Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
Sa, Jason K, Chang, Nakho, Lee, Hye Won, Cho, Hee Jin, Ceccarelli, Michele, Cerulo, Luigi, Yin, Jinlong, Kim, Sung Soo, Caruso, Francesca P, Lee, Mijeong, Kim, Donggeon, Oh, Young Taek, Lee, Yeri, Her, Nam-Gu, Min, Byeongkwi, Kim, Hye-Jin, Jeong, Da Eun, Kim, Hye-Mi, Kim, Hyunho, Chung, Seok, Woo, Hyun Goo, Lee, Jeongwu, Kong, Doo-Sik, Seol, Ho Jun, Lee, Jung-Il, Kim, Jinho, Park, Woong-Yang, Wang, Qianghu, Sulman, Erik P, Heimberger, Amy B, Lim, Michael, Park, Jong Bae, Iavarone, Antonio, Verhaak, Roel G W, Nam, Do-Hyun
Published in Genome Biology (26.08.2020)
Published in Genome Biology (26.08.2020)
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Phase 1 study of capmatinib in MET‐positive solid tumor patients: Dose escalation and expansion of selected cohorts
Bang, Yung‐Jue, Su, Wu‐Chou, Schuler, Martin, Nam, Do‐Hyun, Lim, Wan Teck, Bauer, Todd M., Azaro, Analia, Poon, Ronnie Tung Ping, Hong, David, Lin, Chia‐Chi, Akimov, Mikhail, Ghebremariam, Samson, Zhao, Sylvia, Giovannini, Monica, Ma, Brigette
Published in Cancer science (01.02.2020)
Published in Cancer science (01.02.2020)
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Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2
Wang, Jia, Cheng, Peng, Pavlyukov, Marat S, Yu, Hai, Zhang, Zhuo, Kim, Sung-Hak, Minata, Mutsuko, Mohyeldin, Ahmed, Xie, Wanfu, Chen, Dongquan, Goidts, Violaine, Frett, Brendan, Hu, Wenhao, Li, Hongyu, Shin, Yong Jae, Lee, Yeri, Nam, Do-Hyun, Kornblum, Harley I, Wang, Maode, Nakano, Ichiro
Published in The Journal of clinical investigation (01.08.2017)
Published in The Journal of clinical investigation (01.08.2017)
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Molecular changes in solitary fibrous tumor progression
Park, Hyung Kyu, Yu, Dan Bi, Sung, Minjung, Oh, Ensel, Kim, Mingi, Song, Ji-Young, Lee, Mi-Sook, Jung, Kyungsoo, Noh, Ka-Won, An, Sungbin, Song, Kyoung, Nam, Do-Hyun, Kim, Yu Jin, Choi, Yoon-La
Published in Journal of molecular medicine (Berlin, Germany) (01.10.2019)
Published in Journal of molecular medicine (Berlin, Germany) (01.10.2019)
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The molecular landscape of glioma in patients with Neurofibromatosis 1
D'Angelo, Fulvio, Ceccarelli, Michele, Tala, Garofano, Luciano, Zhang, Jing, Frattini, Véronique, Caruso, Francesca P, Lewis, Genevieve, Alfaro, Kristin D, Bauchet, Luc, Berzero, Giulia, Cachia, David, Cangiano, Mario, Capelle, Laurent, de Groot, John, DiMeco, Francesco, Ducray, François, Farah, Walid, Finocchiaro, Gaetano, Goutagny, Stéphane, Kamiya-Matsuoka, Carlos, Lavarino, Cinzia, Loiseau, Hugues, Lorgis, Véronique, Marras, Carlo E, McCutcheon, Ian, Nam, Do-Hyun, Ronchi, Susanna, Saletti, Veronica, Seizeur, Romuald, Slopis, John, Suñol, Mariona, Vandenbos, Fanny, Varlet, Pascale, Vidaud, Dominique, Watts, Colin, Tabar, Viviane, Reuss, David E, Kim, Seung-Ki, Meyronet, David, Mokhtari, Karima, Salvador, Hector, Bhat, Krishna P, Eoli, Marica, Sanson, Marc, Lasorella, Anna, Iavarone, Antonio
Published in Nature Medicine (01.01.2019)
Published in Nature Medicine (01.01.2019)
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Spatiotemporal Evolution of the Primary Glioblastoma Genome
Kim, Jinkuk, Lee, In-Hee, Cho, Hee Jin, Park, Chul-Kee, Jung, Yang-Soon, Kim, Yanghee, Nam, So Hee, Kim, Byung Sup, Johnson, Mark D., Kong, Doo-Sik, Seol, Ho Jun, Lee, Jung-Il, Joo, Kyeung Min, Yoon, Yeup, Park, Woong-Yang, Lee, Jeongwu, Park, Peter J., Nam, Do-Hyun
Published in Cancer cell (14.09.2015)
Published in Cancer cell (14.09.2015)
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FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2
Lee, Yeri, Kim, Kang Ho, Kim, Dong Geon, Cho, Hee Jin, Kim, Yeonghwan, Rheey, Jinguen, Shin, Kayoung, Seo, Yun Jee, Choi, Yeon-Sook, Lee, Jung-Il, Lee, Jeongwu, Joo, Kyeung Min, Nam, Do-Hyun
Published in PloS one (07.10.2015)
Published in PloS one (07.10.2015)
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Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities
Oh, Sejin, Yeom, Jeonghun, Cho, Hee Jin, Kim, Ju-Hwa, Yoon, Seon-Jin, Kim, Hakhyun, Sa, Jason K., Ju, Shinyeong, Lee, Hwanho, Oh, Myung Joon, Lee, Wonyeop, Kwon, Yumi, Li, Honglan, Choi, Seunghyuk, Han, Jang Hee, Chang, Jong Hee, Choi, Eunsuk, Kim, Jayeon, Her, Nam-Gu, Kim, Se Hoon, Kang, Seok-Gu, Paek, Eunok, Nam, Do-Hyun, Lee, Cheolju, Kim, Hyun Seok
Published in Nature communications (03.07.2020)
Published in Nature communications (03.07.2020)
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