Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma
Sharpe, Hayley J., Pau, Gregoire, Dijkgraaf, Gerrit J., Basset-Seguin, Nicole, Modrusan, Zora, Januario, Thomas, Tsui, Vickie, Durham, Alison B., Dlugosz, Andrzej A., Haverty, Peter M., Bourgon, Richard, Tang, Jean Y., Sarin, Kavita Y., Dirix, Luc, Fisher, David C., Rudin, Charles M., Sofen, Howard, Migden, Michael R., Yauch, Robert L., de Sauvage, Frederic J.
Published in Cancer cell (09.03.2015)
Published in Cancer cell (09.03.2015)
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Basal Cell Carcinoma Preferentially Arises from Stem Cells within Hair Follicle and Mechanosensory Niches
Peterson, Shelby C., Eberl, Markus, Vagnozzi, Alicia N., Belkadi, Abdelmadjid, Veniaminova, Natalia A., Verhaegen, Monique E., Bichakjian, Christopher K., Ward, Nicole L., Dlugosz, Andrzej A., Wong, Sunny Y.
Published in Cell stem cell (02.04.2015)
Published in Cell stem cell (02.04.2015)
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Obesity accelerates hair thinning by stem cell-centric converging mechanisms
Morinaga, Hironobu, Mohri, Yasuaki, Grachtchouk, Marina, Asakawa, Kyosuke, Matsumura, Hiroyuki, Oshima, Motohiko, Takayama, Naoya, Kato, Tomoki, Nishimori, Yuriko, Sorimachi, Yuriko, Takubo, Keiyo, Suganami, Takayoshi, Iwama, Atsushi, Iwakura, Yoichiro, Dlugosz, Andrzej A., Nishimura, Emi K.
Published in Nature (London) (08.07.2021)
Published in Nature (London) (08.07.2021)
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Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles
Grunberg, Nil, Pevsner-Fischer, Meirav, Goshen-Lago, Tal, Diment, Judith, Stein, Yaniv, Lavon, Hagar, Mayer, Shimrit, Levi-Galibov, Oshrat, Friedman, Gil, Ofir-Birin, Yifat, Syu, Li-Jyun, Migliore, Cristina, Shimoni, Eyal, Stemmer, Salomon M, Brenner, Baruch, Dlugosz, Andrzej A, Lyden, David, Regev-Rudzki, Neta, Ben-Aharon, Irit, Scherz-Shouval, Ruth
Published in Cancer research (Chicago, Ill.) (01.04.2021)
Published in Cancer research (Chicago, Ill.) (01.04.2021)
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Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin
Coulombe, Pierre A, DePianto, Daryle, Kerns, Michelle L, Dlugosz, Andrzej A
Published in Nature genetics (01.10.2010)
Published in Nature genetics (01.10.2010)
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Dual and opposing roles of primary cilia in medulloblastoma development
Alvarez-Buylla, Arturo, Han, Young-Goo, Kim, Hong Joo, Dlugosz, Andrzej A, Ellison, David W, Gilbertson, Richard J
Published in Nature medicine (01.09.2009)
Published in Nature medicine (01.09.2009)
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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis
Reiter, Jeremy F, Wong, Sunny Y, Seol, Allen D, So, Po-Lin, Ermilov, Alexandre N, Bichakjian, Christopher K, Epstein, Ervin H, Dlugosz, Andrzej A
Published in Nature medicine (01.09.2009)
Published in Nature medicine (01.09.2009)
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Hedgehog/Ras interactions regulate early stages of pancreatic cancer
Pasca di Magliano, Marina, Sekine, Shigeki, Ermilov, Alexandre, Ferris, Jenny, Dlugosz, Andrzej A, Hebrok, Matthias
Published in Genes & development (15.11.2006)
Published in Genes & development (15.11.2006)
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Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
Veniaminova, Natalia A., Jia, Yunlong Y., Hartigan, Adrien M., Huyge, Thomas J., Tsai, Shih-Ying, Grachtchouk, Marina, Nakagawa, Seitaro, Dlugosz, Andrzej A., Atwood, Scott X., Wong, Sunny Y.
Published in Cell reports (Cambridge) (26.09.2023)
Published in Cell reports (Cambridge) (26.09.2023)
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Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling
Ermilov, Alexandre N, Kumari, Archana, Li, Libo, Joiner, Ariell M, Grachtchouk, Marina A, Allen, Benjamin L, Dlugosz, Andrzej A, Mistretta, Charlotte M
Published in PLoS genetics (28.11.2016)
Published in PLoS genetics (28.11.2016)
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Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin
Veniaminova, Natalia A., Grachtchouk, Marina, Doane, Owen J., Peterson, Jamie K., Quigley, David A., Lull, Madison V., Pyrozhenko, Daryna V., Nair, Raji R., Patrick, Matthew T., Balmain, Allan, Dlugosz, Andrzej A., Tsoi, Lam C., Wong, Sunny Y.
Published in Developmental cell (04.11.2019)
Published in Developmental cell (04.11.2019)
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Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation
Harms, Paul W, Collie, Angela M B, Hovelson, Daniel H, Cani, Andi K, Verhaegen, Monique E, Patel, Rajiv M, Fullen, Douglas R, Omata, Kei, Dlugosz, Andrzej A, Tomlins, Scott A, Billings, Steven D
Published in Modern pathology (01.03.2016)
Published in Modern pathology (01.03.2016)
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Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice
Verhaegen, Monique E, Harms, Paul W, Van Goor, Julia J, Arche, Jacob, Patrick, Matthew T, Wilbert, Dawn, Zabawa, Haley, Grachtchouk, Marina, Liu, Chia-Jen, Hu, Kevin, Kelly, Michael C, Chen, Ping, Saunders, Thomas L, Weidinger, Stephan, Syu, Li-Jyun, Runge, John S, Gudjonsson, Johann E, Wong, Sunny Y, Brownell, Isaac, Cieslik, Marcin, Udager, Aaron M, Chinnaiyan, Arul M, Tsoi, Lam C, Dlugosz, Andrzej A
Published in The Journal of clinical investigation (01.04.2022)
Published in The Journal of clinical investigation (01.04.2022)
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Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations
Grachtchouk, Marina, Pero, Joanna, Yang, Steven H, Ermilov, Alexandre N, Michael, L Evan, Wang, Aiqin, Wilbert, Dawn, Patel, Rajiv M, Ferris, Jennifer, Diener, James, Allen, Mary, Lim, Seokchun, Syu, Li-Jyun, Verhaegen, Monique, Dlugosz, Andrzej A
Published in The Journal of clinical investigation (01.05.2011)
Published in The Journal of clinical investigation (01.05.2011)
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Corrigendum to “Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma” [Neoplasia, Volume 21, Issue 3 (2019) 322–330]
Choi, Jae Eun, Verhaegen, Monique E., Yazdani, Sahr, Malik, Rohit, Harms, Paul W., Mangelberger, Doris, Tien, Jean, Cao, Xuhong, Wang, Yuping, Cieślik, Marcin, Gurkan, Jonathan, Yazdani, Mishaal, Jing, Xiaojun, Juckette, Kristin, Su, Fengyun, Wang, Rui, Zhou, Bing, Apel, Ingrid J., Wang, Shaomeng, Dlugosz, Andrzej A., Chinnaiyan, Arul M.
Published in Neoplasia (New York, N.Y.) (01.09.2024)
Published in Neoplasia (New York, N.Y.) (01.09.2024)
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Corrigendum to “Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma” [Neoplasia, Volume 21, Issue 3 (2019) 322–330]
Choi, Jae Eun, Verhaegen, Monique E., Yazdani, Sahr, Malik, Rohit, Harms, Paul W., Mangelberger, Doris, Tien, Jean, Cao, Xuhong, Wang, Yuping, Cieślik, Marcin, Gurkan, Jonathan, Yazdani, Mishaal, Jing, Xiaojun, Juckette, Kristin, Su, Fengyun, Wang, Rui, Zhou, Bing, Apel, Ingrid J., Wang, Shaomeng, Dlugosz, Andrzej A., Chinnaiyan, Arul M.
Published in Neoplasia (New York, N.Y.) (01.05.2024)
Published in Neoplasia (New York, N.Y.) (01.05.2024)
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Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis
Di Girolamo, Daniela, Ambrosio, Raffaele, De Stefano, Maria A, Mancino, Giuseppina, Porcelli, Tommaso, Luongo, Cristina, Di Cicco, Emery, Scalia, Giulia, Vecchio, Luigi Del, Colao, Annamaria, Dlugosz, Andrzej A, Missero, Caterina, Salvatore, Domenico, Dentice, Monica
Published in The Journal of clinical investigation (01.06.2016)
Published in The Journal of clinical investigation (01.06.2016)
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Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance
Liu, Hong Xiang, Ermilov, Alexandre, Grachtchouk, Marina, Li, Libo, Gumucio, Deborah L., Dlugosz, Andrzej A., Mistretta, Charalotte M.
Published in Developmental biology (01.10.2013)
Published in Developmental biology (01.10.2013)
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Distinct Gene Expression Profiles of Viral- and Nonviral-Associated Merkel Cell Carcinoma Revealed by Transcriptome Analysis
Harms, Paul W., Patel, Rajiv M., Verhaegen, Monique E., Giordano, Thomas J., Nash, Kevin T., Johnson, Craig N., Daignault, Stephanie, Thomas, Dafydd G., Gudjonsson, Johann E., Elder, James T., Dlugosz, Andrzej A., Johnson, Timothy M., Fullen, Douglas R., Bichakjian, Christopher K.
Published in Journal of investigative dermatology (01.04.2013)
Published in Journal of investigative dermatology (01.04.2013)
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Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease
Trieu, Kenneth G., Tsai, Shih-Ying, Eberl, Markus, Ju, Virginia, Ford, Noah C., Doane, Owen J., Peterson, Jamie K., Veniaminova, Natalia A., Grachtchouk, Marina, Harms, Paul W., Swartling, Fredrik J., Dlugosz, Andrzej A., Wong, Sunny Y.
Published in Cell reports (Cambridge) (03.05.2022)
Published in Cell reports (Cambridge) (03.05.2022)
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