Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis
Chakraborty, Debomita, Šumová, Barbora, Mallano, Tatjana, Chen, Chih-Wei, Distler, Alfiya, Bergmann, Christina, Ludolph, Ingo, Horch, Raymund E, Gelse, Kolja, Ramming, Andreas, Distler, Oliver, Schett, Georg, Šenolt, Ladislav, Distler, Jörg H W
Published in Nature communications (24.10.2017)
Published in Nature communications (24.10.2017)
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Journal Article
Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis
Huang, Jingang, Beyer, Christian, Palumbo-Zerr, Katrin, Zhang, Yun, Ramming, Andreas, Distler, Alfiya, Gelse, Kolja, Distler, Oliver, Schett, Georg, Wollin, Lutz, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.05.2016)
Published in Annals of the rheumatic diseases (01.05.2016)
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Journal Article
Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss
Lin, Neng-Yu, Chen, Chih-Wei, Kagwiria, Rosebeth, Liang, Ruifang, Beyer, Christian, Distler, Alfiya, Luther, Julia, Engelke, Klaus, Schett, Georg, Distler, Jörg HW
Published in Annals of the rheumatic diseases (01.06.2016)
Published in Annals of the rheumatic diseases (01.06.2016)
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Journal Article
Signature of circulating microRNAs in osteoarthritis
Beyer, Christian, Zampetaki, Anna, Lin, Neng-Yu, Kleyer, Arnd, Perricone, Carlo, Iagnocco, Annamaria, Distler, Alfiya, Langley, Sarah R, Gelse, Kolja, Sesselmann, Stefan, Lorenzini, Rolando, Niemeier, Andreas, Swoboda, Bernd, Distler, Jörg H W, Santer, Peter, Egger, Georg, Willeit, Johann, Mayr, Manuel, Schett, Georg, Kiechl, Stefan
Published in Annals of the rheumatic diseases (01.03.2015)
Published in Annals of the rheumatic diseases (01.03.2015)
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Journal Article
Author Correction: Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis
Chakraborty, Debomita, Šumová, Barbora, Mallano, Tatjana, Chen, Chih-Wei, Distler, Alfiya, Bergmann, Christina, Ludolph, Ingo, Horch, Raymund E, Gelse, Kolja, Ramming, Andreas, Distler, Oliver, Schett, Georg, Šenolt, Ladislav, Distler, Jörg H W
Published in Nature communications (08.12.2021)
Published in Nature communications (08.12.2021)
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Journal Article
Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies
Dees, Clara, Beyer, Christian, Distler, Alfiya, Soare, Alina, Zhang, Yun, Palumbo-Zerr, Katrin, Distler, Oliver, Schett, Georg, Sandner, Peter, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.08.2015)
Published in Annals of the rheumatic diseases (01.08.2015)
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Journal Article
Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis
Krämer, Marlene, Dees, Clara, Huang, Jingang, Schlottmann, Inga, Palumbo-Zerr, Katrin, Zerr, Pawel, Gelse, Kolja, Beyer, Christian, Distler, Alfiya, Marquez, Victor E, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.04.2013)
Published in Annals of the rheumatic diseases (01.04.2013)
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Journal Article
Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability
Distler, Alfiya, Lang, Veronika, Del Vecchio, Tina, Huang, Jingang, Zhang, Yun, Beyer, Christian, Lin, Neng-Yu, Palumbo-Zerr, Katrin, Distler, Oliver, Schett, Georg, Distler, Jörg HW
Published in Annals of the rheumatic diseases (01.06.2014)
Published in Annals of the rheumatic diseases (01.06.2014)
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Journal Article
Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease
Zerr, Pawel, Palumbo-Zerr, Katrin, Distler, Alfiya, Tomcik, Michal, Vollath, Stefan, Munoz, Luis E., Beyer, Christian, Dees, Clara, Egberts, Friederike, Tinazzi, Ilaria, Del Galdo, Francesco, Distler, Oliver, Schett, Georg, Spriewald, Bernd M., Distler, Jörg H.W.
Published in Blood (04.10.2012)
Published in Blood (04.10.2012)
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Journal Article
Cardiomyopathy in Murine Models of Systemic Sclerosis
Venalis, Paulius, Kumánovics, Gábor, Schulze‐Koops, Hendrik, Distler, Alfiya, Dees, Clara, Zerr, Pawel, Palumbo‐Zerr, Katrin, Czirják, László, Mackevic, Zygmunt, Lundberg, Ingrid E., Distler, Oliver, Schett, Georg, Distler, Jörg H. W.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2015)
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Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis
Palumbo-Zerr, Katrin, Zerr, Pawel, Distler, Alfiya, Fliehr, Judith, Mancuso, Rossella, Huang, Jingang, Mielenz, Dirk, Tomcik, Michal, Fürnrohr, Barbara G, Scholtysek, Carina, Dees, Clara, Beyer, Christian, Krönke, Gerhard, Metzger, Daniel, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Nature medicine (01.02.2015)
Published in Nature medicine (01.02.2015)
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The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis
Dees, Clara, Schlottmann, Inga, Funke, Robin, Distler, Alfiya, Palumbo-Zerr, Katrin, Zerr, Pawel, Lin, Neng-Yu, Beyer, Christian, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.06.2014)
Published in Annals of the rheumatic diseases (01.06.2014)
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Journal Article
Vitamin D receptor regulates TGF-β signalling in systemic sclerosis
Zerr, Pawel, Vollath, Stefan, Palumbo-Zerr, Katrin, Tomcik, Michal, Huang, Jingang, Distler, Alfiya, Beyer, Christian, Dees, Clara, Gela, Kolja, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.03.2015)
Published in Annals of the rheumatic diseases (01.03.2015)
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Journal Article
Autophagy regulates TNFα-mediated joint destruction in experimental arthritis
Lin, Neng-Yu, Beyer, Christian, Gießl, Andreas, Kireva, Trayana, Scholtysek, Carina, Uderhardt, Stefan, Munoz, Luis Enrique, Dees, Clara, Distler, Alfiya, Wirtz, Stefan, Krönke, Gerhard, Spencer, Brian, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.05.2013)
Published in Annals of the rheumatic diseases (01.05.2013)
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Journal Article
Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis
Maurer, Britta, Distler, Alfiya, Suliman, Yossra A, Gay, Renate E, Michel, Beat A, Gay, Steffen, Distler, Jörg H W, Distler, Oliver
Published in Annals of the rheumatic diseases (01.10.2014)
Published in Annals of the rheumatic diseases (01.10.2014)
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Journal Article
JAK1-dependent transphosphorylation of JAK2 limits the antifibrotic effects of selective JAK2 inhibitors on long-term treatment
Zhang, Yun, Liang, Ruifang, Chen, Chih-Wei, Mallano, Tatjana, Dees, Clara, Distler, Alfiya, Reich, Adam, Bergmann, Christina, Ramming, Andreas, Gelse, Kolja, Mielenz, Dirk, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.08.2017)
Published in Annals of the rheumatic diseases (01.08.2017)
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Journal Article
Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse
Ledein, Laetitia, Léger, Bertrand, Dees, Clara, Beyer, Christian, Distler, Alfiya, Vettori, Serena, Boukaiba, Rachid, Bidouard, Jean Pierre, Schaefer, Matthias, Pernerstorfer, Josef, Ruetten, Hartmut, Jagerschmidt, Alexandre, Janiak, Philip, Distler, Jörg H.W., Distler, Oliver, Illiano, Stéphane
Published in British journal of pharmacology (01.09.2020)
Published in British journal of pharmacology (01.09.2020)
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Journal Article
Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling
Beyer, Christian, Zenzmaier, Christoph, Palumbo-Zerr, Katrin, Mancuso, Rossella, Distler, Alfiya, Dees, Clara, Zerr, Pawel, Huang, Jingang, Maier, Christiane, Pachowsky, Milena L, Friebe, Andreas, Sandner, Peter, Distler, Oliver, Schett, Georg, Berger, Peter, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.07.2015)
Published in Annals of the rheumatic diseases (01.07.2015)
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Journal Article
Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis
Beyer, Christian, Reichert, Helena, Akan, Hümeyra, Mallano, Tatjana, Schramm, Amelie, Dees, Clara, Palumbo-Zerr, Katrin, Lin, Neng Yu, Distler, Alfiya, Gelse, Kolja, Varga, John, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.07.2013)
Published in Annals of the rheumatic diseases (01.07.2013)
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Journal Article
Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling
Distler, Alfiya, Deloch, Lisa, Huang, Jingang, Dees, Clara, Lin, Neng-Yu, Palumbo-Zerr, Katrin, Beyer, Christian, Weidemann, Alexander, Distler, Oliver, Schett, Georg, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.09.2013)
Published in Annals of the rheumatic diseases (01.09.2013)
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