Detailed analysis of Mdivi-1 effects on complex I and respiratory supercomplex assembly
Marx, Nico, Ritter, Nadine, Disse, Paul, Seebohm, Guiscard, Busch, Karin B.
Published in Scientific reports (24.08.2024)
Published in Scientific reports (24.08.2024)
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Journal Article
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids
Renner, Henrik, Grabos, Martha, Becker, Katharina J, Kagermeier, Theresa E, Wu, Jie, Otto, Mandy, Peischard, Stefan, Zeuschner, Dagmar, TsyTsyura, Yaroslav, Disse, Paul, Klingauf, Jürgen, Leidel, Sebastian A, Seebohm, Guiscard, Schöler, Hans R, Bruder, Jan M
Published in eLife (03.11.2020)
Published in eLife (03.11.2020)
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Journal Article
Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix Formation
Disse, Paul, Aymanns, Isabel, Mücher, Lena, Sandmann, Sarah, Varghese, Julian, Ritter, Nadine, Strutz-Seebohm, Nathalie, Seebohm, Guiscard, Peischard, Stefan
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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Journal Article
Pharmacological Potential of 3-Benzazepines in NMDAR-Linked Pathophysiological Processes
Ritter, Nadine, Disse, Paul, Wünsch, Bernhard, Seebohm, Guiscard, Strutz-Seebohm, Nathalie
Published in Biomedicines (05.05.2023)
Published in Biomedicines (05.05.2023)
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Journal Article
MAPT genotype-dependent mitochondrial aberration and ROS production trigger dysfunction and death in cortical neurons of patients with hereditary FTLD
Korn, Lisanne, Speicher, Anna M., Schroeter, Christina B., Gola, Lukas, Kaehne, Thilo, Engler, Alexander, Disse, Paul, Fernández-Orth, Juncal, Csatári, Júlia, Naumann, Michael, Seebohm, Guiscard, Meuth, Sven G., Schöler, Hans R., Wiendl, Heinz, Kovac, Stjepana, Pawlowski, Matthias
Published in Redox biology (01.02.2023)
Published in Redox biology (01.02.2023)
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Journal Article
A novel fluorescent labeling compound for GluN2A containing N-methyl-d-aspartate receptors identified by autodisplay-based screening
Dombovski, Alexander, Steigerwald, Ruben, Ritter, Nadine, Disse, Paul, Goerges, Gunnar, Osthues, Jana, Aymanns, Isabel, Dilkaute, Carina, Schreiber, Julian, Düfer, Martina, Seebohm, Guiscard, Wünsch, Bernhard, Jose, Joachim
Published in Journal of pharmaceutical analysis (01.07.2024)
Published in Journal of pharmaceutical analysis (01.07.2024)
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Journal Article
Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis
Rohrbeck, Matthias, Hoerr, Verena, Piccini, Ilaria, Greber, Boris, Schulte, Jan Sebastian, Hübner, Sara-Sophie, Jeworutzki, Elena, Theiss, Carsten, Matschke, Veronika, Stypmann, Jörg, Unger, Andreas, Ho, Huyen Tran, Disse, Paul, Strutz-Seebohm, Nathalie, Faber, Cornelius, Müller, Frank Ulrich, Ludwig, Stephan, Rescher, Ursula, Linke, Wolfgang A, Klingel, Karin, Busch, Karin, Peischard, Stefan, Seebohm, Guiscard
Published in Cells (Basel, Switzerland) (01.02.2023)
Published in Cells (Basel, Switzerland) (01.02.2023)
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Journal Article
Unveiling the Complex problem with Mdivi-1
Marx, Nico, Ritter, Nadine, Disse, Paul, Seebohm, Guiscard, Busch, Karin B.
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2024)
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2024)
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Journal Article
Interfering with mitochondrial dynamics during neuronal differentiation alters the organization of the mitochondrial inner membrane
Marx, Nico, Disse, Paul, Aymanns, Isabel, Seebohm, Guiscard, Busch, Karin B.
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2022)
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2022)
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Journal Article
Evaluation of SK-N-SH Cells as a Model for NMDA Receptor Induced Toxicity
Goerges, Gunnar, Disse, Paul, Peischard, Stefan, Ritter, Nadine, Brenker, Christoph, Seebohm, Guiscard, Strutz-Seebohm, Nathalie, Schreiber, Julian A
Published in Cellular physiology and biochemistry (30.08.2024)
Published in Cellular physiology and biochemistry (30.08.2024)
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Journal Article
Indazole as a Phenol Bioisostere: Structure–Affinity Relationships of GluN2B-Selective NMDA Receptor Antagonists
Lüken, Judith, Goerges, Gunnar, Ritter, Nadine, Disse, Paul, Schreiber, Julian A., Schmidt, Judith, Frehland, Bastian, Schepmann, Dirk, Seebohm, Guiscard, Wünsch, Bernhard
Published in Journal of medicinal chemistry (24.08.2023)
Published in Journal of medicinal chemistry (24.08.2023)
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Journal Article
Negative allosteric modulators of NMDA receptors with GluN2B subunit: synthesis of β-aminoalcohols by epoxide opening and subsequent rearrangement
Korff, Marvin, Lüken, Judith, Schmidt, Judith, Schepmann, Dirk, Goerges, Gunnar, Ritter, Nadine, Disse, Paul, Schreiber, Julian A, Seebohm, Guiscard, Wnsch, Bernhard
Published in Organic & biomolecular chemistry (27.09.2023)
Published in Organic & biomolecular chemistry (27.09.2023)
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Journal Article
A novel NMDA receptor test model based on hiPSC-derived neural cells
Disse, Paul, Aymanns, Isabel, Ritter, Nadine, Peischard, Stefan, Korn, Lisanne, Wiendl, Heinz, Pawlowski, Matthias, Kovac, Stjepana, Meuth, Sven G., Budde, Thomas, Strutz-Seebohm, Nathalie, Wünsch, Bernhard, Seebohm, Guiscard
Published in Biological chemistry (28.03.2023)
Published in Biological chemistry (28.03.2023)
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Journal Article
Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system
Peischard, Stefan, Möller, Melina, Disse, Paul, Ho, Huyen Tran, Verkerk, Arie O., Strutz-Seebohm, Nathalie, Budde, Thomas, Meuth, Sven G., Schweizer, Patrick A., Morris, Silke, Mücher, Lena, Eisner, Verónica, Thomas, Dierk, Klingel, Karin, Busch, Karin, Seebohm, Guiscard
Published in Cellular and molecular life sciences : CMLS (01.08.2022)
Published in Cellular and molecular life sciences : CMLS (01.08.2022)
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Journal Article
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination
Kapell, Hannah, Fazio, Luca, Dyckow, Julia, Schwarz, Sophia, Cruz-Herranz, Andrés, Mayer, Christina, Campos, Joaquin, D'Este, Elisa, Möbius, Wiebke, Cordano, Christian, Pröbstel, Anne-Katrin, Gharagozloo, Marjan, Zulji, Amel, Narayanan Naik, Venu, Delank, Anna, Cerina, Manuela, Müntefering, Thomas, Lerma-Martin, Celia, Sonner, Jana K, Sin, Jung Hyung, Disse, Paul, Rychlik, Nicole, Sabeur, Khalida, Chavali, Manideep, Srivastava, Rajneesh, Heidenreich, Matthias, Fitzgerald, Kathryn C, Seebohm, Guiscard, Stadelmann, Christine, Hemmer, Bernhard, Platten, Michael, Jentsch, Thomas J, Engelhardt, Maren, Budde, Thomas, Nave, Klaus-Armin, Calabresi, Peter A, Friese, Manuel A, Green, Ari J, Acuna, Claudio, Rowitch, David H, Meuth, Sven G, Schirmer, Lucas
Published in The Journal of clinical investigation (01.04.2023)
Published in The Journal of clinical investigation (01.04.2023)
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Journal Article
Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives
Ritter, Nadine, Disse, Paul, Aymanns, Isabel, Mücher, Lena, Schreiber, Julian A., Brenker, Christoph, Strünker, Timo, Schepmann, Dirk, Budde, Thomas, Strutz-Seebohm, Nathalie, Ametamey, Simon M., Wünsch, Bernhard, Seebohm, Guiscard
Published in Molecular neurobiology (01.12.2023)
Published in Molecular neurobiology (01.12.2023)
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Journal Article
Optimized synthesis and pharmacological evaluation of HCN channel inhibitor EC18
Patberg, Marius, Oniani, Tengiz, Disse, Paul, Peischard, Stefan, Vinnenberg, Laura, Zobeiri, Mehrnoush, Romanelli, Maria N., Epping, Lisa, Wiendl, Heinz, Meuth, Sven G., Hundehege, Petra, Seebohm, Guiscard, Budde, Thomas, Junker, Anna
Published in Archiv der Pharmazie (Weinheim) (01.06.2023)
Published in Archiv der Pharmazie (Weinheim) (01.06.2023)
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