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Published in The Journal of biological chemistry (27.06.2014)
Published in The Journal of biological chemistry (27.06.2014)
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Simov, Vladimir, Altman, Michael D., Bianchi, Elisabetta, DelRizzo, Sonia, DiNunzio, Edward N., Feng, Guo, Goldenblatt, Peter, Ingenito, Raffaele, Johnson, Scott A., Mansueto, My Sam, Mayhood, Todd, Mortison, Jonathan D., Serebrov, Victor, Sondey, Christopher, Sriraman, Venkat, Tucker, Thomas J., Walji, Abbas, Wan, Hui, Yue, Yingzi, Stoeck, Alexander, DiMauro, Erin F.
Published in European journal of medicinal chemistry (15.11.2021)
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Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab
Hernandez, Lorraine D., Kroh, Heather K., Hsieh, Edward, Yang, Xiaoyu, Beaumont, Maribel, Sheth, Payal R., DiNunzio, Edward, Rutherford, Stacey A., Ohi, Melanie D., Ermakov, Grigori, Xiao, Li, Secore, Susan, Karczewski, Jerzy, Racine, Fred, Mayhood, Todd, Fischer, Paul, Sher, Xinwei, Gupta, Pulkit, Lacy, D. Borden, Therien, Alex G.
Published in Journal of molecular biology (07.04.2017)
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Morris, Erick J, Jha, Sharda, Restaino, Clifford R, Dayananth, Priya, Zhu, Hugh, Cooper, Alan, Carr, Donna, Deng, Yongi, Jin, Weihong, Black, Stuart, Long, Brian, Liu, Jenny, Dinunzio, Edward, Windsor, William, Zhang, Rumin, Zhao, Shuxia, Angagaw, Minilik H, Pinheiro, Elaine M, Desai, Jagdish, Xiao, Li, Shipps, Gerald, Hruza, Alan, Wang, James, Kelly, Joe, Paliwal, Sunil, Gao, Xiaolei, Babu, Boga Sobhana, Zhu, Liang, Daublain, Pierre, Zhang, Ling, Lutterbach, Bart A, Pelletier, Marc R, Philippar, Ulrike, Siliphaivanh, Phieng, Witter, David, Kirschmeier, Paul, Bishop, W Robert, Hicklin, Daniel, Gilliland, D Gary, Jayaraman, Lata, Zawel, Leigh, Fawell, Stephen, Samatar, Ahmed A
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Chang, Wonsuk, Altman, Michael D, Lesburg, Charles A, Perera, Samanthi A, Piesvaux, Jennifer A, Schroeder, Gottfried K, Wyss, Daniel F, Cemerski, Saso, Chen, Yiping, DiNunzio, Edward, Haidle, Andrew M, Ho, Thu, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny E, Lacey, Brian M, Laskey, Jason, Lim, Jongwon, Long, Brian J, Ma, Yanhong, Maddess, Matthew L, Pan, Bo-Sheng, Presland, Jeremy P, Spooner, Edward, Steinhuebel, Dietrich, Truong, Quang, Zhang, Zhibo, Fu, Jianmin, Addona, George H, Northrup, Alan B, Parmee, Emma, Tata, James R, Bennett, David Jonathan, Cumming, Jared N, Siu, Tony, Trotter, B. Wesley
Published in Journal of medicinal chemistry (14.04.2022)
Published in Journal of medicinal chemistry (14.04.2022)
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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9
Petrilli, Whitney L., Adam, Gregory C., Erdmann, Roman S., Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P., Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M., Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P., Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M., Strack, Alison M., Youm, Hyewon, Zhao, Kake, Zink, Deborah L., Zokian, Hratch, Addona, George H., Akinsanya, Karen, Tata, James R., Xiong, Yusheng, Imbriglio, Jason E.
Published in Cell chemical biology (16.01.2020)
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Fragment-based screening approach reveals non-orthosteric pockets in the search for allosteric inhibitors of tau-tubulin kinase 1
Hayes, Robert P., DiNunzio, Edward, Yazdani, Mahdieh, Sikorska, Justyna, Chen, Yili, Tyagarajan, Sriram, Park, Younghee, Lee, Amy, Reyes, Cesar, Burschowsky, Daniel, Zebisch, Matthias, Ou, Yangsi, Bukhtiyarova, Marina, Niroomand, Shahriar, Tian, Yuan, Stachel, Shawn, Su, Hua, Hicks, Jacqueline D., Wyss, Daniel F.
Published in Acta crystallographica. Section A, Foundations and advances (07.07.2023)
Published in Acta crystallographica. Section A, Foundations and advances (07.07.2023)
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Broad coverage of genetically diverse strains of Clostridium difficile by actoxumab and bezlotoxumab predicted by in vitro neutralization and epitope modeling
Hernandez, Lorraine D, Racine, Fred, Xiao, Li, DiNunzio, Edward, Hairston, Nichelle, Sheth, Payal R, Murgolo, Nicholas J, Therien, Alex G
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Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy
Skudlarek, Jason W., Cooke, Andrew J., Mitchell, Helen J., Babaoglu, Kerim, Shaw, Anthony W., Tong, Ling, Nomland, Ashley B., Labroli, Marc, Sha, Deyou, Mulhearn, James J., Wu, Chengwei, Li, Sarah W., Beshore, Douglas C., Hughes, Jonathan M. E., Jouffroy, Matthieu, Wang, Hao, Balibar, Carl J., Painter, Ronald E., Shen, Pamela, Lange, Henry S., Ishchenko, Andrii, Chen, Yun-Ting, Klein, Daniel J., Tracy, Rodger W., Miller, Randy R., Cabalu, Tamara D., Wu, Zhe, Leithead, Andrew, Scapin, Giovanna, Hruza, Alan W., Dzhekieva, Liudmila, Bukhtiyarova, Marina, Homsher, Michelle F., Xu, Min, Bahnck-Teets, Carolyn, McKenney, David, Buevich, Alexei V., Liu, Jian, Zhang, Li-Kang, Meng, Tao, Kelly, Terri, DiNunzio, Edward, Soisson, Stephen, Cheng, Robert K. Y., Hennig, Michael, Raheem, Izzat, Walker, Scott S.
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Published in Journal of medicinal chemistry (12.09.2024)
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Plotkin, Michael A., Labroli, Marc, Schubert, Jeffrey, Shaw, Anthony, Schlegel, Kelly-Ann S., Berger, Richard, Cooke, Andrew J., Hayes, Robert P., Armacost, Kira A., Kinek, Keith, Krosky, Paula, Burlein, Christine, Meng, Shi, DiNunzio, Edward, Murray, Edward M., Agrawal, Sony, Madeira, Maria, Flattery, Amy, Yao, Huifang, Leithead, Andrew, Rose, William A, Cox, Christopher, Tellers, David M., McKenna, Philip M., Raheem, Izzat
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Published in ACS medicinal chemistry letters (08.08.2024)
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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9
Petrilli, Whitney L, Adam, Gregory C, Erdmann, Roman S, Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P, Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M, Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P, Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M, Strack, AlisonM, Youm, Hyewon, Zhao, Kake, Zink, Deborah L, Zokian, Hratch, Addona, George H, Akinsanya, Karen, Tata, James R, Xiong, Yusheng, Imbriglio, Jason E
Published in Cell chemical biology (18.02.2021)
Published in Cell chemical biology (18.02.2021)
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Elucidation of DnaE as the Antibacterial Target of the Natural Product, Nargenicin
Painter, Ronald E., Adam, Gregory C., Arocho, Marta, DiNunzio, Edward, Donald, Robert G.K., Dorso, Karen, Genilloud, Olga, Gill, Charles, Goetz, Michael, Hairston, Nichelle N., Murgolo, Nicholas, Nare, Bakela, Olsen, David B., Powles, Maryann, Racine, Fred, Su, Jing, Vicente, Francisca, Wisniewski, Douglas, Xiao, Li, Hammond, Milton, Young, Katherine
Published in Chemistry & biology (22.10.2015)
Published in Chemistry & biology (22.10.2015)
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