Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State
Indurthi, Dinesh C, Lewis, Trevor M, Ahring, Philip K, Balle, Thomas, Chebib, Mary, Absalom, Nathan L
Published in PloS one (23.08.2016)
Published in PloS one (23.08.2016)
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Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Activity for the Treatment of Neurodegenerative Disorders
Kowal, Natalia, Indurthi, Dinesh, Ahring, Philip, Chebib, Mary, Olafsdottir, Elin, Balle, Thomas
Published in Molecules (Basel, Switzerland) (27.01.2019)
Published in Molecules (Basel, Switzerland) (27.01.2019)
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CHRFAM7A: A human specific fusion gene, accounts for the translational gap for cholinergic strategies in Alzheimer's disease
Szigeti, Kinga, Ihnatovych, Ivanna, Birkaya, Barbara, Chen, Ziqiang, Ouf, Aya, Indurthi, Dinesh C., Bard, Jonathan E., Kann, Julien, Adams, Alexandrea, Chaves, Lee, Sule, Norbert, Reisch, Joan S., Pavlik, Valory, Benedict, Ralph H.B., Auerbach, Anthony, Wilding, Gregory
Published in EBioMedicine (01.09.2020)
Published in EBioMedicine (01.09.2020)
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Clostridia: the importance of their exceptional substrate and metabolite diversity for biofuel and biorefinery applications
Tracy, Bryan P, Jones, Shawn W, Fast, Alan G, Indurthi, Dinesh C, Papoutsakis, Eleftherios T
Published in Current opinion in biotechnology (01.06.2012)
Published in Current opinion in biotechnology (01.06.2012)
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Journal Article
Novel Approach for the Search for Chemical Scaffolds with Dual Activity with Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor-A Perspective for the Treatment of Neurodegenerative Disorders
Kowal, Natalia M, Indurthi, Dinesh C, Ahring, Philip K, Chebib, Mary, Olafsdottir, Elin S, Balle, Thomas
Published in Molecules (Basel, Switzerland) (27.01.2019)
Published in Molecules (Basel, Switzerland) (27.01.2019)
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Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry
Indurthi, Dinesh C., Qudah, Taima, Liao, Vivian W., Ahring, Philip K., Lewis, Trevor M., Balle, Thomas, Chebib, Mary, Absalom, Nathan L.
Published in Pharmacological research (01.01.2019)
Published in Pharmacological research (01.01.2019)
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Small RNAs in the genus Clostridium
Chen, Yili, Indurthi, Dinesh C, Jones, Shawn W, Papoutsakis, Eleftherios T
Published in mBio (25.01.2011)
Published in mBio (25.01.2011)
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Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1
Indurthi, Dinesh C., Pera, Elena, Kim, Hye-Lim, Chu, Cindy, McLeod, Malcolm D., Michael McIntosh, J., Absalom, Nathan L., Chebib, Mary
Published in Biochemical pharmacology (01.05.2014)
Published in Biochemical pharmacology (01.05.2014)
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CHRFAM7A diversifies human immune adaption through Ca2+ signalling and actin cytoskeleton reorganization
Szigeti, Kinga, Ihnatovych, Ivanna, Notari, Emily, Dorn, Ryu P., Maly, Ivan, He, Muye, Birkaya, Barbara, Prasad, Shreyas, Byrne, Robin Schwartz, Indurthi, Dinesh C., Nimmer, Erik, Heo, Yuna, Retfalvi, Kolos, Chaves, Lee, Sule, Norbert, Hofmann, Wilma A., Auerbach, Anthony, Wilding, Gregory, Bae, Yongho, Reynolds, Jessica
Published in EBioMedicine (01.05.2024)
Published in EBioMedicine (01.05.2024)
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Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis
Crown, Scott B, Indurthi, Dinesh C, Ahn, Woo Suk, Choi, Jungik, Papoutsakis, Eleftherios T, Antoniewicz, Maciek R
Published in Biotechnology journal (01.03.2011)
Published in Biotechnology journal (01.03.2011)
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Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4–α4 interface
Ahring, Philip K., Olsen, Jeppe A., Nielsen, Elsebet Ø., Peters, Dan, Pedersen, Martin H.F., Rohde, Line A., Kastrup, Jette S., Shahsavar, Azadeh, Indurthi, Dinesh C., Chebib, Mary, Gajhede, Michael, Balle, Thomas
Published in Neuropharmacology (01.05.2015)
Published in Neuropharmacology (01.05.2015)
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Journal Article
Ligand Binding at the α4-α4 Agonist-Binding Site of the α4β2 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State
Indurthi, Dinesh C., Lewis, Trevor M., Ahring, Philip K., Balle, Thomas, Chebib, Mary, Absalom, Nathan L.
Published in PloS one (23.08.2016)
Published in PloS one (23.08.2016)
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Journal Article
Lower Tubulin Expression in Glioblastoma Stem Cells Attenuates Efficacy of Microtubule-Targeting Agents
Abbassi, Ramzi H, Recasens, Ariadna, Indurthi, Dinesh C, Johns, Terrance G, Stringer, Brett W, Day, Bryan W, Munoz, Lenka
Published in ACS pharmacology & translational science (13.12.2019)
Published in ACS pharmacology & translational science (13.12.2019)
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Journal Article
Gain-of-function GABRB3 variants identified in vigabatrin-hypersensitive epileptic encephalopathies
Absalom, Nathan L, Liao, Vivian W Y, Kothur, Kavitha, Indurthi, Dinesh C, Bennetts, Bruce, Troedson, Christopher, Mohammad, Shekeeb S, Gupta, Sachin, McGregor, Iain S, Bowen, Michael T, Lederer, Damien, Mary, Sandrine, De Waele, Liesbeth, Jansen, Katrien, Gill, Deepak, Kurian, Manju A, McTague, Amy, Møller, Rikke S, Ahring, Philip K, Dale, Russell C, Chebib, Mary
Published in Brain communications (01.01.2020)
Published in Brain communications (01.01.2020)
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Journal Article
Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors
Petersen, Ida Nymann, Crestey, François, Jensen, Anders A, Indurthi, Dinesh C, Pedersen, Henrik, Andreasen, Jesper T, Balle, Thomas, Kristensen, Jesper L
Published in ACS medicinal chemistry letters (09.04.2015)
Published in ACS medicinal chemistry letters (09.04.2015)
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Journal Article
Exploiting ligand selectivity to understand allosteric receptor opening
Indurthi, Dinesh C., Balle, Thomas, Ahring, Philip K., Chebib, Mary, Lewis, Trever M., Absalom, Nathan L.
Published in Biochemical pharmacology (15.10.2015)
Published in Biochemical pharmacology (15.10.2015)
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