3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice
Rathnayake, Athri D, Zheng, Jian, Kim, Yunjeong, Perera, Krishani Dinali, Mackin, Samantha, Meyerholz, David K, Kashipathy, Maithri M, Battaile, Kevin P, Lovell, Scott, Perlman, Stanley, Groutas, William C, Chang, Kyeong-Ok
Published in Science Translational Medicine (19.08.2020)
Published in Science Translational Medicine (19.08.2020)
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Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus‑2 3C-like Protease
Dampalla, Chamandi S., Rathnayake, Athri D., Galasiti Kankanamalage, Anushka C., Kim, Yunjeong, Perera, Krishani Dinali, Nguyen, Harry Nhat, Miller, Matthew J., Madden, Trent K., Picard, Hunter R., Thurman, Hayden A., Kashipathy, Maithri M., Liu, Lijun, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Published in Journal of medicinal chemistry (09.06.2022)
Published in Journal of medicinal chemistry (09.06.2022)
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The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2
Huang, Ruiqi, Warner Jenkins, Gabrielle, Kim, Yunjeong, Stanfield, Robyn L, Singh, Amrinder, Martinez-Yamout, Maria, Kroon, Gerard J, Torres, Jonathan L, Jackson, Abigail M, Kelley, Abigail, Shaabani, Namir, Zeng, Baisen, Bacica, Michael, Chen, Wen, Warner, Christopher, Radoicic, Jasmina, Joh, Joongho, Dinali Perera, Krishani, Sang, Huldah, Kim, Tae, Yao, Jianxiu, Zhao, Fangzhu, Sok, Devin, Burton, Dennis R, Allen, Jeff, Harriman, William, Mwangi, Waithaka, Chung, Donghoon, Teijaro, John R, Ward, Andrew B, Dyson, H Jane, Wright, Peter E, Wilson, Ian A, Chang, Kyeong-Ok, McGregor, Duncan, Smider, Vaughn V
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2023)
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Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus
Perera, Krishani Dinali, Johnson, David, Lovell, Scott, Groutas, William C, Chang, Kyeong-Ok, Kim, Yunjeong
Published in Microbiology spectrum (31.08.2022)
Published in Microbiology spectrum (31.08.2022)
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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
Dampalla, Chamandi S., Zheng, Jian, Perera, Krishani Dinali, Wong, Lok-Yin Roy, Meyerholz, David K., Nguyen, Harry Nhat, Kashipathy, Maithri M., Battaile, Kevin P., Lovell, Scott, Kim, Yunjeong, Perlman, Stanley, Groutas, William C., Chang, Kyeong-Ok
Published in Proceedings of the National Academy of Sciences - PNAS (20.07.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (20.07.2021)
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Interactions of viruses and the humoral innate immune response
Maloney, Bailey E., Perera, Krishani Dinali, Saunders, Danielle R.D., Shadipeni, Naemi, Fleming, Sherry D.
Published in Clinical immunology (Orlando, Fla.) (01.03.2020)
Published in Clinical immunology (Orlando, Fla.) (01.03.2020)
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Structure-Guided Design of Potent Inhibitors of SARS-CoV‑2 3CL Protease: Structural, Biochemical, and Cell-Based Studies
Dampalla, Chamandi S, Rathnayake, Athri D, Perera, Krishani Dinali, Jesri, Abdul-Rahman M, Nguyen, Harry Nhat, Miller, Matthew J, Thurman, Hayden A, Zheng, Jian, Kashipathy, Maithri M, Battaile, Kevin P, Lovell, Scott, Perlman, Stanley, Kim, Yunjeong, Groutas, William C, Chang, Kyeong-Ok
Published in Journal of medicinal chemistry (23.12.2021)
Published in Journal of medicinal chemistry (23.12.2021)
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Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor
Perera, Krishani Dinali, Rathnayake, Athri D., Liu, Hongwei, Pedersen, Niels C., Groutas, William C., Chang, Kyeong-Ok, Kim, Yunjeong
Published in Veterinary microbiology (01.10.2019)
Published in Veterinary microbiology (01.10.2019)
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Protease inhibitors broadly effective against feline, ferret and mink coronaviruses
Perera, Krishani Dinali, Galasiti Kankanamalage, Anushka C., Rathnayake, Athri D., Honeyfield, Amanda, Groutas, William, Chang, Kyeong-Ok, Kim, Yunjeong
Published in Antiviral research (01.12.2018)
Published in Antiviral research (01.12.2018)
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SARS-CoV-2 Omicron (B.1.1.529) Infection of Wild White-Tailed Deer in New York City
Vandegrift, Kurt J, Yon, Michele, Surendran Nair, Meera, Gontu, Abhinay, Ramasamy, Santhamani, Amirthalingam, Saranya, Neerukonda, Sabarinath, Nissly, Ruth H, Chothe, Shubhada K, Jakka, Padmaja, LaBella, Lindsey, Levine, Nicole, Rodriguez, Sophie, Chen, Chen, Sheersh Boorla, Veda, Stuber, Tod, Boulanger, Jason R, Kotschwar, Nathan, Aucoin, Sarah Grimké, Simon, Richard, Toal, Katrina L, Olsen, Randall J, Davis, James J, Bold, Dashzeveg, Gaudreault, Natasha N, Dinali Perera, Krishani, Kim, Yunjeong, Chang, Kyeong-Ok, Maranas, Costas D, Richt, Juergen A, Musser, James M, Hudson, Peter J, Kapur, Vivek, Kuchipudi, Suresh V
Published in Viruses (12.12.2022)
Published in Viruses (12.12.2022)
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Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies
Dampalla, Chamandi S., Nguyen, Harry Nhat, Rathnayake, Athri D., Kim, Yunjeong, Perera, Krishani Dinali, Madden, Trent K., Thurman, Hayden A., Machen, Alexandra J., Kashipathy, Maithri M., Liu, Lijun, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Published in ACS pharmacology & translational science (13.01.2023)
Published in ACS pharmacology & translational science (13.01.2023)
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Post-infection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
Dampalla, Chamandi S, Zhang, Jian, Perera, Krishani Dinali, Lok-Yin Roy Wong, Meyerholz, David K, Nguyen, Harry Nhat, Kashipathy, Maithri M, Battaile, Kevin P, Lovell, Scott, Kim, Yunjeong, Perlman, Stanley, Groutas, William C, Chang, Kyeong-Ok
Published in bioRxiv (05.02.2021)
Published in bioRxiv (05.02.2021)
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