Comprehensive analysis of cutaneous and uveal melanoma liver metastases
Hoefsmit, Esmee P, Rozeman, Elisa A, Van, Trieu My, Dimitriadis, Petros, Krijgsman, Oscar, Conway, Jordan W, Pires da Silva, Ines, van der Wal, Jacqueline E, Ketelaars, Steven L C, Bresser, Kaspar, Broeks, Annegien, Kerkhoven, Ron M, Reeves, Jason W, Warren, Sarah, Kvistborg, Pia, Scolyer, Richard A, Kapiteijn, Ellen W, Peeper, Daniel S, Long, Georgina V, Schumacher, Ton N M, Blank, Christian U
Published in Journal for immunotherapy of cancer (01.12.2020)
Published in Journal for immunotherapy of cancer (01.12.2020)
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Journal Article
Interferon-gamma signature as prognostic and predictive marker in macroscopic stage III melanoma
Versluis, Judith M, Blankenstein, Stephanie A, Dimitriadis, Petros, Wilmott, James S, Elens, Robert, Blokx, Willeke A M, van Houdt, Winan, Menzies, Alexander Maxwell, Schrage, Yvonne M, Wouters, Michel W J M, Sanders, Joyce, Broeks, Annegien, Scolyer, Richard A, Suijkerbuijk, Karijn P M, Long, Georgina V, Akkooi, Alexander C J van, Blank, Christian U
Published in Journal for immunotherapy of cancer (27.04.2024)
Published in Journal for immunotherapy of cancer (27.04.2024)
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Journal Article
Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors
Kaptein, Paulien, Jacoberger-Foissac, Celia, Dimitriadis, Petros, Voabil, Paula, de Bruijn, Marjolein, Brokamp, Simone, Reijers, Irene, Versluis, Judith, Nallan, Gahyathiri, Triscott, Hannah, McDonald, Elizabeth, Tay, Joshua, Long, Georgina V, Blank, Christian U, Thommen, Daniela S, Teng, Michele W L
Published in Science translational medicine (27.04.2022)
Published in Science translational medicine (27.04.2022)
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Journal Article
The impact of emotional distress on pathologic response and survival after neoadjuvant combination immune checkpoint blockade (ICB) in high-risk stage III melanoma
Reijers, Irene L.M., Fraterman, Itske, Dimitriadis, Petros, Broeks, Annegien, Gonzalez, Maria, Menzies, Alexander M., Kapiteijn, Ellen, Van Der Veldt, Astrid Aplonia Maria, Suijkerbuijk, Karijn, Hospers, Geke, Long, Georgina V., Blank, Christian U., van de Poll-Franse, Lonneke
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Revisiting the optimal neoadjuvant immunotherapy regimen in resectable stage III melanoma based on the interferon gamma signature: A pooled analysis
Lucas, Minke W., Dimitriadis, Petros, Reijers, Irene L.M., Menzies, Alexander M., Rozeman, Elisa A., Versluis, Judith M., Huang, Alexander Chan Chi, Cornelissen, Sten, Broeks, Annegien, Scolyer, Richard A., Mitchell, Tara C., Long, Georgina V., Blank, Christian U.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma
Reijers, Irene L M, Rao, Disha, Versluis, Judith M, Menzies, Alexander M, Dimitriadis, Petros, Wouters, Michel W, Spillane, Andrew J, Klop, Willem M C, Broeks, Annegien, Bosch, Linda J W, Lopez-Yurda, Marta, van Houdt, Winan J, Rawson, Robert V, Grijpink-Ongering, Lindsay G, Gonzalez, Maria, Cornelissen, Sten, Bouwman, Jasper, Sanders, Joyce, Plasmeijer, Elsemieke, Elshot, Yannick S, Scolyer, Richard A, van de Wiel, Bart A, Peeper, Daniel S, van Akkooi, Alexander C J, Long, Georgina V, Blank, Christian U
Published in The Journal of experimental medicine (01.05.2023)
Published in The Journal of experimental medicine (01.05.2023)
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Journal Article
The interferon-gamma (IFN-y) signature from baseline tumor material predicts pathologic response after neoadjuvant ipilimumab (IPI) + nivolumab (NIVO) in stage III melanoma
Reijers, Irene L.M., Dimitriadis, Petros, Rozeman, Elisa A., Krijgsman, Oscar, Cornelissen, Sten, Bosch, Linda J.W., Broeks, Annegien, Menzies, Alexander M., van de Wiel, Bart A., Scolyer, Richard A., Long, Georgina V., Blank, Christian U.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Acidity‐mediated induction of FoxP3+ regulatory T cells
Rao, Disha, Stunnenberg, Johanna A., Lacroix, Ruben, Dimitriadis, Petros, Kaplon, Joanna, Verburg, Fabienne, van Royen, Paula T., Hoefsmit, Esmée P., Renner, Kathrin, Blank, Christian U., Peeper, Daniel S.
Published in European journal of immunology (01.06.2023)
Published in European journal of immunology (01.06.2023)
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Journal Article
The prognostic value of the interferon-gamma (IFNγ) signature in patients with macroscopic stage III melanoma treated with and without adjuvant systemic therapy
Versluis, Judith M., Blankenstein, Stephanie, Dimitriadis, Petros, Sanders, Joyce, Hoefakker, Willem, Broeks, Annegien, van Houdt, Winan J., Schrage, Yvonne M., Wouters, Michel W.J.M., Van Akkooi, Alexander Christopher Jonathan, Blank, Christian U.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
IMPemBra, a phase 2 study comparing pembrolizumab with intermittent/short‐term dual MAPK pathway inhibition plus pembrolizumab in patients with melanoma harboring the BRAFV600 mutation: Three-year survival data and translational analyses
Rozeman, Elisa A., Versluis, Judith M., Hoefsmit, Esmée P, Dimitriadis, Petros, Grijpink-Ongering, Lindsay G., Sikorska, Karolina, van de Wiel, Bart A., Heeres, Birthe C, Flohil, Claudi, Kvistborg, Pia, van den Broek, Daan, Broeks, Annegien, de Groot, Jan Willem, Wilgenhof, Sofie, Vollebergh, Marieke A., van Thienen, Johannes V., Haanen, John B. A. G., Blank, Christian U.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Association between pretreatment emotional distress and neoadjuvant immune checkpoint blockade response in melanoma
Fraterman, Itske, Reijers, Irene L. M., Dimitriadis, Petros, Broeks, Annegien, Gonzalez, M., Menzies, A. M. M., Lopez-Yurda, Marta, Kapiteijn, Ellen, van der Veldt, Astrid A. M., Suijkerbuijk, Karijn P. M., Hospers, Geke A. P., Long, Georgina V., Blank, Christian U., van de Poll-Franse, Lonneke V.
Published in Nature medicine (01.12.2023)
Published in Nature medicine (01.12.2023)
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Journal Article
MeVa2.1.dOVA and MeVa2.2.dOVA: two novel BRAFV600E-driven mouse melanoma cell lines to study tumor immune resistance
Rao, Disha, Lacroix, Ruben, Rooker, Alex, Gomes, Tainá, Stunnenberg, Johanna A, Valenti, Mesele, Dimitriadis, Petros, Lin, Chun-Pu, de Bruijn, Beaunelle, Krijgsman, Oscar, Ligtenberg, Maarten A, Peeper, Daniel S, Blank, Christian U
Published in Melanoma research (01.02.2023)
Published in Melanoma research (01.02.2023)
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Journal Article
Abstract 3412: 36-months and 18-months relapse-free survival after (neo)adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma patients - update of the OpACIN and OpACIN-neo trials
Blank, Christian U., Versluis, Judith M., Rozeman, Elisa A., Menzies, Alexander M., Reijers, Irene L., Krijgsman, Oscar, Hoefsmit, Esmée P., van de Wiel, Bart A., Sikorska, Karolina, Bierman, Carolien, Dimitriadis, Petros, Gonzalez, Maria, Broeks, Annegien, Kerkhoven, Ron M., Spillane, Andrew J., Haanen, John B., van Houdt, Winan J., Saw, Robyn P., Eriksson, Hanna, van Akkooi, Alexander C., Scolyer, Richard A., Schumacher, Ton N., Long, Georgina V.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
The IMPemBra trial, a phase II study comparing pembrolizumab with intermittent/short‐term dual MAPK pathway inhibition plus pembrolizumab in melanoma patients harboring the BRAFV600 mutation
Rozeman, Elisa A., Versluis, Judith M., Sikorska, Karolina, Lacroix, Ruben, Grijpink-Ongering, Lindsay G, Heeres, Birthe, Van De Wiel, Bart A., Dimitriadis, Petros, Sari, Ayşegül, Heijmink, Stijn, Kvistborg, Pia, van den Broek, Daan, Broeks, Annegien, de Groot, Jan Willem, Wilgenhof, Sofie, Vollebergh, Marieke Anne, Van Thienen, Johannes V., Haanen, John B. A. G., Blank, Christian U.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Personalized combination of neoadjuvant domatinostat, nivolumab and ipilimumab in macroscopic stage III melanoma patients stratified according to the interferon-gamma signature: The DONIMI study
Reijers, Irene L.M., Dimitriadis, Petros, Rozeman, Elisa A., Versluis, Judith M., Broeks, Annegien, Bosch, Linda J.W., Bouwman, Jasper, Cornelissen, Sten, Krijgsman, Oscar, Gonzalez, Maria, Rao, Disha, Grijpink-Ongering, Lindsay G, van Dijk, Marloes, Spillane, Andrew, Scolyer, Richard A., Van De Wiel, Bart A., Menzies, Alexander M., Van Akkooi, Alexander Christopher Jonathan, Long, Georgina V., Blank, Christian U.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Twenty-four months RFS and updated toxicity data from OpACIN-neo: A study to identify the optimal dosing schedule of neoadjuvant ipilimumab (IPI) and nivolumab (NIVO) in stage III melanoma
Rozeman, Elisa A., Reijers, Irene L.M., Hoefsmit, Esmée P, Sikorska, Karolina, Krijgsman, Oscar, Van De Wiel, Bart A., Dimitriadis, Petros, Eriksson, Hanna, Gonzalez, Maria, Grijpink-Ongering, Lindsay G, Kerkhoven, Ron M., Broeks, Annegien, Klop, Willem M.C., Spillane, Andrew, Saw, Robyn PM, Van Akkooi, Alexander Christopher Jonathan, Scolyer, Richard A., Menzies, Alexander M., Long, Georgina V., Blank, Christian U.
Published in JOURNAL OF CLINICAL ONCOLOGY (20.05.2020)
Published in JOURNAL OF CLINICAL ONCOLOGY (20.05.2020)
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Journal Article
Conference Proceeding
IMPemBra: a phase 2 study comparing pembrolizumab with intermittent/short-term dual MAPK pathway inhibition plus pembrolizumab in patients with melanoma harboring the BRAFV600 mutation
Rozeman, Elisa A, Versluis, Judith M, Sikorska, Karolina, Hoefsmit, Esmée P, Dimitriadis, Petros, Rao, Disha, Lacroix, Ruben, Grijpink-Ongering, Lindsay G, Lopez-Yurda, Marta, Heeres, Birthe C, van de Wiel, Bart A, Flohil, Claudie, Sari, Aysegul, Heijmink, Stijn W T P J, van den Broek, Daan, Broeks, Annegien, de Groot, Jan Willem B, Vollebergh, Marieke A, Wilgenhof, Sofie, van Thienen, Johannes V, Haanen, John B A G, Blank, Christian U
Published in Journal for immunotherapy of cancer (01.07.2023)
Published in Journal for immunotherapy of cancer (01.07.2023)
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Journal Article