Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles
Flaumenhaft, Robert, Dilks, James R., Richardson, Jennifer, Alden, Eva, Patel-Hett, Sunita R., Battinelli, Elisabeth, Klement, Giannoula L., Sola-Visner, Martha, Italiano, Joseph E.
Published in Blood (29.01.2009)
Published in Blood (29.01.2009)
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Journal Article
Endobrevin/VAMP-8–dependent dense granule release mediates thrombus formation in vivo
Graham, Gwenda J., Ren, Qiansheng, Dilks, James R., Blair, Price, Whiteheart, Sidney W., Flaumenhaft, Robert
Published in Blood (30.07.2009)
Published in Blood (30.07.2009)
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Journal Article
Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1
Dowal, Louisa, Sim, Derek S, Dilks, James R, Blair, Price, Beaudry, Sarah, Denker, Bradley M, Koukos, Georgios, Kuliopulos, Athan, Flaumenhaft, Robert
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2011)
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Journal Article
Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar
Aisiku, Omozuanvbo, Peters, Christian G., De Ceunynck, Karen, Ghosh, Chandra C., Dilks, James R., Fustolo-Gunnink, Susanna F., Huang, Mingdong, Dockendorff, Chris, Parikh, Samir M., Flaumenhaft, Robert
Published in Blood (19.03.2015)
Published in Blood (19.03.2015)
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Journal Article
The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation
Revollo, Leila, Merrill-Skoloff, Glenn, De Ceunynck, Karen, Dilks, James R., Guo, Shihui, Bordoli, Mattia R., Peters, Christian G., Noetzli, Leila, Ionescu, Andreia, Rosen, Vicki, Italiano, Joseph E., Whitman, Malcolm, Flaumenhaft, Robert
Published in Blood (06.01.2022)
Published in Blood (06.01.2022)
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Journal Article
The Platelet Actin Cytoskeleton Associates with SNAREs and Participates in α-Granule Secretion
Woronowicz, Kamil, Dilks, James R, Rozenvayn, Nataliya, Dowal, Louisa, Blair, Price S, Peters, Christian G, Woronowicz, Lucyna, Flaumenhaft, Robert
Published in Biochemistry (Easton) (01.06.2010)
Published in Biochemistry (Easton) (01.06.2010)
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Journal Article
Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents
Jasuja, Reema, Passam, Freda H, Kennedy, Daniel R, Kim, Sarah H, van Hessem, Lotte, Lin, Lin, Bowley, Sheryl R, Joshi, Sucharit S, Dilks, James R, Furie, Bruce, Furie, Barbara C, Flaumenhaft, Robert
Published in The Journal of clinical investigation (01.06.2012)
Published in The Journal of clinical investigation (01.06.2012)
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Journal Article
Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Exocytosis
Koseoglu, Secil, Dilks, James R, Peters, Christian G, Fitch-Tewfik, Jennifer L, Fadel, Nathalie A, Jasuja, Reema, Italiano, Joseph E, Haynes, Christy L, Flaumenhaft, Robert
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2013)
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Journal Article
The actin cytoskeleton differentially regulates platelet α-granule and dense-granule secretion
Flaumenhaft, Robert, Dilks, James R., Rozenvayn, Nataliya, Monahan-Earley, Rita A., Feng, Dian, Dvorak, Ann M.
Published in Blood (15.05.2005)
Published in Blood (15.05.2005)
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Journal Article
Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor
Dockendorff, Chris, Aisiku, Omozuanvbo, VerPlank, Lynn, Dilks, James R, Smith, Daniel A, Gunnink, Susanna F, Dowal, Louisa, Negri, Joseph, Palmer, Michelle, MacPherson, Lawrence, Schreiber, Stuart L, Flaumenhaft, Robert
Published in ACS medicinal chemistry letters (08.03.2012)
Published in ACS medicinal chemistry letters (08.03.2012)
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Journal Article
Effects Of Biased PAR1 Ligands On Platelets and Endothelial Cells
Aisiku, Omozuanvbo R., Peters, Christian G., Gunnink, Suzanne, Dilks, James R., Dockendorff, Chris, Flaumenhaft, Robert
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation
Bekendam, Roelof H, Srila, Gopal, Bendapudi, Pavan K, Dilks, James R, Lin, Lin, Bowley, Sheryl, Stopa, Jack, Huang, Mingdong, Furie, Bruce, Croce, Kevin, Flaumenhaft, Robert
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Acyl-Protein Thioesterase 1 Functions in Palmitoylation/Depalmitoylation Cycles of G Proteins and Regulates Platelet Activation
Dowal, Louisa M., Dilks, James R., Fadel, Nathalie A., Aisiku, Omozuanvbo R., Merrill-Skoloff, Glenn, Flaumenhaft, Robert C.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
An Allosteric Modulator of PAR1 Demonstrates Selective Inhibition of G Protein Coupling and Impairs Thrombus Formation In Vivo
Aisiku, Omozuanvbo R, Dockendorff, Chris, Gunnick, Suzanne F, Smith, Daniel A., Dilks, James R., Dowal, Louisa M., Flaumenhaft, Robert C.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Secretion and Thrombus Formation In Vivo
Flaumenhaft, Robert C., Koseoglu, Secil, Dilks, James R., Peters, Christian G., Fadel, Nathalie A., Jasuja, Reema, Haynes, Christy L.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Development Of Second Generation Thiol Isomerase Inhibitors To Prevent Thrombus Formation
Kennedy, Daniel R, Nag, Partha P, Galinski, Christine N., Bowley, Sheryl, Bekendam, Roelof H., Dilks, James R., Scalise, Alissa A, van Hessem, Lotte, Pu, Jun, Pilyugina, Tatiana, Dandapani, Sivaraman, Munoz, Benito, Flaumenhaft, Robert
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
The Platelet Actin Cytoskeleton Associates Directly with Syntaxin-4 and Participates in α-Granule Secretion
Flaumenhaft, Robert, Dilks, James R., Rozenvayn, Nataliya, Woronowicz, Kamil
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
A Chemical Genetic Analysis of Platelet Activation Identifies An Antithrombotic Allosteric Modulator That Acts through Helix 8 of Par1
Dowal, Louisa M., Sim, Derek, Dilks, James R, Blair, Price, Beaudry, Sarah, Denker, Bradley, Koukos, George, Kuliopulos, Athan, Flaumenhaft, Robert
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Journal Article
Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents
Jasuja, Reema, Passam, Freda H, Kennedy, Daniel R, Kim, Sarah H, van Hessem, Lotte, Lin, Lin, Bowley, Sheryl R, Joshi, Sucharit S, Dilks, James R, Furie, Bruce, Furie, Barbara C, Flaumenhaft, Robert
Published in The Journal of clinical investigation (01.06.2012)
Published in The Journal of clinical investigation (01.06.2012)
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Journal Article