High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms
Melby, Jake A, Brown, Kyle A, Gregorich, Zachery R, Roberts, David S, Chapman, Emily A, Ehlers, Lauren E, Gao, Zhan, Larson, Eli J, Jin, Yutong, Lopez, Justin R, Hartung, Jared, Zhu, Yanlong, McIlwain, Sean J, Wang, Daojing, Guo, Wei, Diffee, Gary M, Ge, Ying
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2023)
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Top-down Mass Spectrometry of Sarcomeric Protein Post-translational Modifications from Non-human Primate Skeletal Muscle
Jin, Yutong, Diffee, Gary M., Colman, Ricki J., Anderson, Rozalyn M., Ge, Ying
Published in Journal of the American Society for Mass Spectrometry (01.12.2019)
Published in Journal of the American Society for Mass Spectrometry (01.12.2019)
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Geroprotector drugs and exercise: friends or foes on healthy longevity?
Elliehausen, Christian J, Anderson, Rozalyn M, Diffee, Gary M, Rhoads, Timothy W, Lamming, Dudley W, Hornberger, Troy A, Konopka, Adam R
Published in BMC biology (08.12.2023)
Published in BMC biology (08.12.2023)
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Journal Article
Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of the Sarcomeric Subproteome[S]
Lin, Ziqing, Wei, Liming, Cai, Wenxuan, Zhu, Yanlong, Tucholski, Trisha, Mitchell, Stanford D., Guo, Wei, Ford, Stephen P., Diffee, Gary M., Ge, Ying
Published in Molecular & cellular proteomics (01.03.2019)
Published in Molecular & cellular proteomics (01.03.2019)
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Sarco/endoplasmic reticulum calcium ATPase activity is unchanged despite increased myofilament calcium sensitivity in Zucker type 2 diabetic fatty rat heart
Ng, Yann Huey, Lamberts, Regis R., Jones, Peter P., Sammut, Ivan A., Diffee, Gary M., Wilkins, Gerard T., Baldi, James C.
Published in Scientific reports (07.10.2022)
Published in Scientific reports (07.10.2022)
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Journal Article
Top-Down Proteomics Reveals Myofilament Proteoform Heterogeneity among Various Rat Skeletal Muscle Tissues
Melby, Jake A, Jin, Yutong, Lin, Ziqing, Tucholski, Trisha, Wu, Zhijie, Gregorich, Zachery R, Diffee, Gary M, Ge, Ying
Published in Journal of proteome research (03.01.2020)
Published in Journal of proteome research (03.01.2020)
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Mass Spectrometry-Based Multiomics Identifies Metabolic Signatures of Sarcopenia in Rhesus Monkey Skeletal Muscle
Pergande, Melissa R., Osterbauer, Katie J., Buck, Kevin M., Roberts, David S., Wood, Nina N., Balasubramanian, Priya, Mann, Morgan W., Rossler, Kalina J., Diffee, Gary M., Colman, Ricki J., Anderson, Rozalyn M., Ge, Ying
Published in Journal of proteome research (02.08.2024)
Published in Journal of proteome research (02.08.2024)
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Adiponectin receptor agonist AdipoRon improves skeletal muscle function in aged mice
Balasubramanian, Priya, Schaar, Anne E, Gustafson, Grace E, Smith, Alex B, Howell, Porsha R, Greenman, Angela, Baum, Scott, Colman, Ricki J, Lamming, Dudley W, Diffee, Gary M, Anderson, Rozalyn M
Published in eLife (17.03.2022)
Published in eLife (17.03.2022)
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Journal Article
Treadmill running increases the calcium sensitivity of myofilaments in diabetic rats
Greenman, Angela C, Diffee, Gary M, Power, Amelia S, Wilkins, Gerard T, Gold, Olivia M S, Erickson, Jeffrey R, Baldi, James C
Published in Journal of applied physiology (1985) (01.06.2022)
Published in Journal of applied physiology (1985) (01.06.2022)
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Journal Article
Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications (PTMs) in Skeletal Muscles Identified by Top-down Proteomics
Wei, Liming, Gregorich, Zachery R., Lin, Ziqing, Cai, Wenxuan, Jin, Yutong, McKiernan, Susan H., McIlwain, Sean, Aiken, Judd M., Moss, Richard L., Diffee, Gary M., Ge, Ying
Published in Molecular & cellular proteomics (01.01.2018)
Published in Molecular & cellular proteomics (01.01.2018)
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Journal Article
Top-Down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light-Chain Phosphorylation That Contributes to Sarcopenic Muscle Dysfunction
Gregorich, Zachery R, Peng, Ying, Cai, Wenxuan, Jin, Yutong, Wei, Liming, Chen, Albert J, McKiernan, Susan H, Aiken, Judd M, Moss, Richard L, Diffee, Gary M, Ge, Ying
Published in Journal of proteome research (05.08.2016)
Published in Journal of proteome research (05.08.2016)
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Journal Article
The carbon monoxide prodrug oCOm‐21 increases Ca2+ sensitivity of the cardiac myofilament
Payne, Fergus M., Nie, Samantha, Diffee, Gary M., Wilkins, Gerard T., Larsen, David S., Harrison, Joanne C., Baldi, James C., Sammut, Ivan A.
Published in Physiological reports (01.03.2024)
Published in Physiological reports (01.03.2024)
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Journal Article
Increased myofilament calcium sensitivity is associated with decreased cardiac troponin I phosphorylation in the diabetic rat heart
Greenman, Angela C., Diffee, Gary M., Power, Amelia S., Wilkins, Gerard T., Gold, Olivia M. S., Erickson, Jeffrey R., Baldi, James C.
Published in Experimental physiology (01.11.2021)
Published in Experimental physiology (01.11.2021)
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Journal Article
Sex-Specific Skeletal Muscle Fatigability and Decreased Mitochondrial Oxidative Capacity in Adult Rats Exposed to Postnatal Hyperoxia
Tetri, Laura H, Diffee, Gary M, Barton, Gregory P, Braun, Rudolf K, Yoder, Hannah E, Haraldsdottir, Kristin, Eldridge, Marlowe W, Goss, Kara N
Published in Frontiers in physiology (29.03.2018)
Published in Frontiers in physiology (29.03.2018)
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Sex differences in skeletal muscle alterations in a model of colorectal cancer
Greenman, Angela C., Albrecht, Dawn M., Halberg, Richard B., Diffee, Gary M.
Published in Physiological reports (01.03.2020)
Published in Physiological reports (01.03.2020)
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Journal Article
Moderate intensity, but not high intensity, treadmill exercise training alters power output properties in myocardium from aged rats
Chung, Eunhee, Diffee, Gary M
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.11.2012)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.11.2012)
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Journal Article
Effect of Age and Exercise on the Viscoelastic Properties of Rat Tail Tendon
LaCroix, Andrew S., Duenwald-Kuehl, Sarah E., Brickson, Stacey, Akins, Tiffany L., Diffee, Gary, Aiken, Judd, Vanderby, Ray, Lakes, Roderic S.
Published in Annals of biomedical engineering (01.06.2013)
Published in Annals of biomedical engineering (01.06.2013)
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Journal Article
The carbon monoxide prodrug oCOm-21 increases Ca 2+ sensitivity of the cardiac myofilament
Payne, Fergus M, Nie, Samantha, Diffee, Gary M, Wilkins, Gerard T, Larsen, David S, Harrison, Joanne C, Baldi, James C, Sammut, Ivan A
Published in Physiological reports (01.03.2024)
Published in Physiological reports (01.03.2024)
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Journal Article
Mitochondrial and Metabolic Gene Expression in the Aged Rat Heart
Barton, Gregory P, Sepe, Joseph J, McKiernan, Susan H, Aiken, Judd M, Diffee, Gary M
Published in Frontiers in physiology (23.08.2016)
Published in Frontiers in physiology (23.08.2016)
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