A socio-spatial analysis of pedestrian falls in Aotearoa New Zealand
Watkins, A., Curl, A., Mavoa, S., Tomintz, M., Todd, V., Dicker, B.
Published in Social science & medicine (1982) (01.11.2021)
Published in Social science & medicine (1982) (01.11.2021)
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Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial
Morales-Ramirez, Javier, Bogner, Johannes R, Molina, Jean-Michel, Lombaard, Johan, Dicker, Ira B, Stock, David A, DeGrosky, Michelle, Gartland, Margaret, Pene Dumitrescu, Teodora, Min, Sherene, Llamoso, Cyril, Joshi, Samit R, Lataillade, Max
Published in PloS one (23.10.2018)
Published in PloS one (23.10.2018)
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Mechanistic Studies and Modeling Reveal the Origin of Differential Inhibition of Gag Polymorphic Viruses by HIV-1 Maturation Inhibitors
Lin, Zeyu, Cantone, Joseph, Lu, Hao, Nowicka-Sans, Beata, Protack, Tricia, Yuan, Tian, Yang, Hong, Liu, Zheng, Drexler, Dieter, Regueiro-Ren, Alicia, Meanwell, Nicholas A, Cockett, Mark, Krystal, Mark, Lataillade, Max, Dicker, Ira B
Published in PLoS pathogens (01.11.2016)
Published in PLoS pathogens (01.11.2016)
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Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors
Naidu, B. Narasimhulu, Sorenson, Margaret E., Patel, Manoj, Ueda, Yasutsugu, Banville, Jacques, Beaulieu, Francis, Bollini, Sagarika, Dicker, Ira B., Higley, Helen, Lin, Zeyu, Pajor, Lori, Parker, Dawn D., Terry, Brian J., Zheng, Ming, Martel, Alain, Meanwell, Nicholas A., Krystal, Mark, Walker, Michael A.
Published in Bioorganic & medicinal chemistry letters (01.02.2015)
Published in Bioorganic & medicinal chemistry letters (01.02.2015)
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Changes to the HIV Long Terminal Repeat and to HIV Integrase Differentially Impact HIV Integrase Assembly, Activity, and the Binding of Strand Transfer Inhibitors
Dicker, Ira B., Samanta, Himadri K., Li, Zhufang, Hong, Yang, Tian, Yuan, Banville, Jacques, Remillard, Roger R., Walker, Michael A., Langley, David R., Krystal, Mark
Published in The Journal of biological chemistry (26.10.2007)
Published in The Journal of biological chemistry (26.10.2007)
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An Oral Vaccine against NMDAR1 with Efficacy in Experimental Stroke and Epilepsy
During, Matthew J., Symes, Charles W., Lawlor, Patricia A., Lin, John, Dunning, Jane, Fitzsimons, Helen L., Poulsen, David, Leone, Paola, Xu, Ruian, Dicker, Bridget L., Lipski, Janusz, Young, Deborah
Published in Science (American Association for the Advancement of Science) (25.02.2000)
Published in Science (American Association for the Advancement of Science) (25.02.2000)
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Biochemical Analysis of HIV-1 Integrase Variants Resistant to Strand Transfer Inhibitors
Dicker, Ira B., Terry, Brian, Lin, Zeyu, Li, Zhufang, Bollini, Sagarika, Samanta, Himadri K., Gali, Volodymyr, Walker, Michael A., Krystal, Mark R.
Published in The Journal of biological chemistry (29.08.2008)
Published in The Journal of biological chemistry (29.08.2008)
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Generation and Characterization of Torudokimab (LY3375880): A Monoclonal Antibody That Neutralizes Interleukin-33
Okragly, Angela J, Corwin, Katie Brannon, Elia, Marikka, He, Dongmei, Schroeder, Oliver, Zhang, Qing, Shiyanova, Tatiyana, Bright, Stuart, Dicker, Sarah B, Chlewicki, Lukasz, Truhlar, Stephanie ME, Davies, Julian, Patel, Chetan N, Benschop, Robert J
Published in Journal of inflammation research (01.01.2021)
Published in Journal of inflammation research (01.01.2021)
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Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes
XU, R, JANSON, C. G, LEONE, P, CHEN, Q, DICKER, B, DURING, M. J, MASTAKOV, M, LAWLOR, P, YOUNG, D, MOURAVLEV, A, FITZSIMONS, H, CHOI, K-L, MA, H, DRAGUNOW, M
Published in Gene therapy (01.09.2001)
Published in Gene therapy (01.09.2001)
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Identification and Characterization of BMS-955176, a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Antiviral Spectrum, and Gag Polymorphic Coverage
Nowicka-Sans, Beata, Protack, Tricia, Lin, Zeyu, Li, Zhufang, Zhang, Sharon, Sun, Yongnian, Samanta, Himadri, Terry, Brian, Liu, Zheng, Chen, Yan, Sin, Ny, Sit, Sing-Yuen, Swidorski, Jacob J, Chen, Jie, Venables, Brian L, Healy, Matthew, Meanwell, Nicholas A, Cockett, Mark, Hanumegowda, Umesh, Regueiro-Ren, Alicia, Krystal, Mark, Dicker, Ira B
Published in Antimicrobial agents and chemotherapy (01.07.2016)
Published in Antimicrobial agents and chemotherapy (01.07.2016)
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Discovery and Optimization of Novel Pyrazolopyrimidines as Potent and Orally Bioavailable Allosteric HIV‑1 Integrase Inhibitors
Li, Guo, Meanwell, Nicholas A, Krystal, Mark R, Langley, David R, Naidu, B. Narasimhulu, Sivaprakasam, Prasanna, Lewis, Hal, Kish, Kevin, Khan, Javed A, Ng, Alicia, Trainor, George L, Cianci, Christopher, Dicker, Ira B, Walker, Michael A, Lin, Zeyu, Protack, Tricia, Discotto, Linda, Jenkins, Susan, Gerritz, Samuel W, Pendri, Annapurna
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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Second Generation Inhibitors of HIV‑1 Maturation
Regueiro-Ren, Alicia, Dicker, Ira B, Hanumegowda, Umesh, Meanwell, Nicholas A
Published in ACS medicinal chemistry letters (14.03.2019)
Published in ACS medicinal chemistry letters (14.03.2019)
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Antiviral Activity, Safety, and Exposure–Response Relationships of GSK3532795, a Second-Generation Human Immunodeficiency Virus Type 1 Maturation Inhibitor, Administered as Monotherapy or in Combination With Atazanavir With or Without Ritonavir in a Phase 2a Randomized, Dose-Ranging, Controlled Trial (AI468002)
Hwang, Carey, Schürmann, Dirk, Sobotha, Christian, Boffito, Marta, Sevinsky, Heather, Ray, Neelanjana, Ravindran, Palanikumar, Xiao, Hong, Keicher, Christian, Hüser, Andreas, Krystal, Mark, Dicker, Ira B., Grasela, Dennis, Lataillade, Max
Published in Clinical infectious diseases (01.08.2017)
Published in Clinical infectious diseases (01.08.2017)
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Design and exploration of C-3 benzoic acid bioisosteres and alkyl replacements in the context of GSK3532795 (BMS-955176) that exhibit broad spectrum HIV-1 maturation inhibition
Swidorski, Jacob J., Jenkins, Susan, Hanumegowda, Umesh, Parker, Dawn D., Beno, Brett R., Protack, Tricia, Ng, Alicia, Gupta, Anuradha, Shanmugam, Yoganand, Dicker, Ira B., Krystal, Mark, Meanwell, Nicholas A., Regueiro-Ren, Alicia
Published in Bioorganic & medicinal chemistry letters (15.03.2021)
Published in Bioorganic & medicinal chemistry letters (15.03.2021)
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Scaffold modifications to the 4-(4,4-dimethylpiperidinyl) 2,6-dimethylpyridinyl class of HIV-1 allosteric integrase inhibitors
Parcella, Kyle, Patel, Manoj, Tu, Yong, Eastman, Kyle, Peese, Kevin, Gillis, Eric, Belema, Makonen, Dicker, Ira B., McAuliffe, Brian, Ding, Bo, Falk, Paul, Simmermacher, Jean, Parker, Dawn D., Sivaprakasam, Prasanna, Khan, Javed A., Kish, Kevin, Lewis, Hal, Hanumegowda, Umesh, Jenkins, Susan, Kadow, John F., Krystal, Mark, Meanwell, Nicholas A., Naidu, B. Narasimhulu
Published in Bioorganic & medicinal chemistry (01.08.2022)
Published in Bioorganic & medicinal chemistry (01.08.2022)
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Heterocycle amide isosteres: An approach to overcoming resistance for HIV-1 integrase strand transfer inhibitors
Peese, Kevin M., Naidu, B. Narasimhulu, Patel, Manoj, Li, Chen, Langley, David R., Terry, Brian, Protack, Tricia, Gali, Volodymyr, Lin, Zeyu, Samanta, Himadri K., Zheng, Ming, Jenkins, Susan, Dicker, Ira B., Krystal, Mark R., Meanwell, Nicholas A., Walker, Michael A.
Published in Bioorganic & medicinal chemistry letters (01.02.2020)
Published in Bioorganic & medicinal chemistry letters (01.02.2020)
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The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor
Naidu, B. Narasimhulu, Walker, Michael A., Sorenson, Margaret E., Ueda, Yasutsugu, Matiskella, John D., Connolly, Timothy P., Dicker, Ira B., Lin, Zeyu, Bollini, Sagarika, Terry, Brian J., Higley, Helen, Zheng, Ming, Parker, Dawn D., Wu, Dedong, Adams, Stephen, Krystal, Mark R., Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (01.07.2018)
Published in Bioorganic & medicinal chemistry letters (01.07.2018)
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