First-in-Human Evaluation of Safety, Pharmacokinetics and Muscle Glycogen Lowering of a Novel Glycogen Synthase 1 Inhibitor for the Treatment of Pompe Disease
Ullman, Julie C, Dick, Ryan A, Linzner, Daniela, Minga, Todd, Tep, Samnang, Satterfield, Terrence F, Xi, Yannan, Beattie, David T, Marmon, Tonya, Neutel, Joel M, Chung, Bernard, Leeds, Janet M, Noonberg, Sarah B, Green, Eric M, Bernstein, Harold S
Published in Clinical pharmacology and therapeutics (22.10.2024)
Published in Clinical pharmacology and therapeutics (22.10.2024)
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Journal Article
Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus
Gilmore, Sarah A, Tam, Danny, Cheung, Tara L, Snyder, Chelsea, Farand, Julie, Dick, Ryan, Matles, Mike, Feng, Joy Y, Ramirez, Ricardo, Li, Li, Yu, Helen, Xu, Yili, Barnes, Dwight, Czerwieniec, Gregg, Brendza, Katherine M, Appleby, Todd C, Birkus, Gabriel, Willkom, Madeleine, Kobayashi, Tetsuya, Paoli, Eric, Labelle, Marc, Boesen, Thomas, Tay, Chin H, Delaney, 4th, William E, Notte, Gregory T, Schmitz, Uli, Feierbach, Becket
Published in PloS one (07.12.2022)
Published in PloS one (07.12.2022)
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Journal Article
Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders
Ullman, Julie C, Mellem, Kevin T, Xi, Yannan, Ramanan, Vyas, Merritt, Hanne, Choy, Rebeca, Gujral, Tarunmeet, Young, Lyndsay E A, Blake, Kerrigan, Tep, Samnang, Homburger, Julian R, O'Regan, Adam, Ganesh, Sandya, Wong, Perryn, Satterfield, Terrence F, Lin, Baiwei, Situ, Eva, Yu, Cecile, Espanol, Bryan, Sarwaikar, Richa, Fastman, Nathan, Tzitzilonis, Christos, Lee, Patrick, Reiton, Daniel, Morton, Vivian, Santiago, Pam, Won, Walter, Powers, Hannah, Cummings, Beryl B, Hoek, Maarten, Graham, Robert R, Chandriani, Sanjay J, Bainer, Russell, DePaoli-Roach, Anna A, Roach, Peter J, Hurley, Thomas D, Sun, Ramon C, Gentry, Matthew S, Sinz, Christopher, Dick, Ryan A, Noonberg, Sarah B, Beattie, David T, Morgans, Jr, David J, Green, Eric M
Published in Science translational medicine (17.01.2024)
Published in Science translational medicine (17.01.2024)
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Journal Article
Enzymes and Inhibitors in Neonicotinoid Insecticide Metabolism
Shi, Xueyan, Dick, Ryan A, Ford, Kevin A, Casida, John E
Published in Journal of agricultural and food chemistry (10.06.2009)
Published in Journal of agricultural and food chemistry (10.06.2009)
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Journal Article
Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus
Sarah A Gilmore, Danny Tam, Tara L Cheung, Chelsea Snyder, Julie Farand, Ryan Dick, Mike Matles, Joy Y Feng, Ricardo Ramirez, Li Li, Helen Yu, Yili Xu, Dwight Barnes, Gregg Czerwieniec, Katherine M Brendza, Todd C Appleby, Gabriel Birkus, Madeleine Willkom, Tetsuya Kobayashi, Eric Paoli, Marc Labelle, Thomas Boesen, Chin H Tay, William E Delaney, Gregory T Notte, Uli Schmitz, Becket Feierbach
Published in PloS one (07.12.2022)
Published in PloS one (07.12.2022)
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Journal Article
Discovery of Hepatitis B Virus Surface Antigen Suppressor GS-8873
Kato, Darryl, Choy, Regina Wai-Yan, Canales, Eda, Dick, Ryan A., Lake, April D., Shapiro, Nathan D., Chin, Elbert, Li, Jiayao, Zhang, Jennifer R., Wu, Qiaoyin, Saito, Roland D., Metobo, Sammy, Aktoudianakis, Evangelos, Schroeder, Scott D., Yang, Zheng-Yu, Glatt, Dylan M., Balsitis, Scott, Gamelin, Lindsay, Yu, Mei, Cheng, Guofeng, Delaney, William E., Link, John O.
Published in ACS medicinal chemistry letters (11.04.2024)
Published in ACS medicinal chemistry letters (11.04.2024)
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Journal Article
Nitroso-Imidacloprid Irreversibly Inhibits Rabbit Aldehyde Oxidase
Dick, Ryan A, Kanne, David B, Casida, John E
Published in Chemical research in toxicology (01.12.2007)
Published in Chemical research in toxicology (01.12.2007)
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Journal Article
Identification of Aldehyde Oxidase as the Neonicotinoid Nitroreductase
Dick, Ryan A, Kanne, David B, Casida, John E
Published in Chemical research in toxicology (01.02.2005)
Published in Chemical research in toxicology (01.02.2005)
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Journal Article
Neonicotinoid Nitroguanidine Insecticide Metabolites: Synthesis and Nicotinic Receptor Potency of Guanidines, Aminoguanidines, and Their Derivatives
Kanne, David B, Dick, Ryan A, Tomizawa, Motohiro, Casida, John E
Published in Chemical research in toxicology (01.09.2005)
Published in Chemical research in toxicology (01.09.2005)
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Journal Article
Emergency department charges may be associated with mortality in patients with severe sepsis and septic shock: a cohort study
Mohr, Nicholas M, Dick-Perez, Ryan, Ahmed, Azeemuddin, Harland, Karisa K, Shane, Dan, Miller, Daniel, Miyake, Christine, Kannedy, Levi, Fuller, Brian M, Torner, James C
Published in BMC emergency medicine (29.12.2018)
Published in BMC emergency medicine (29.12.2018)
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Journal Article
A Modern VLF Receiver for use in an Array for VLF Imaging of the D-Region
Cannon, James M., Marshall, Robert A., Dick, Ryan, Fragomeni, Bennett, Wankmueller, Sebastian, Orlandella, Sophia
Published in 2024 United States National Committee of URSI National Radio Science Meeting (USNC-URSI NRSM) (09.01.2024)
Published in 2024 United States National Committee of URSI National Radio Science Meeting (USNC-URSI NRSM) (09.01.2024)
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Conference Proceeding
Structure−Function Relationships of Human Liver Cytochromes P450 3A: Aflatoxin B1 Metabolism as a Probe
Wang, Huifen, Dick, Ryan, Yin, Hequn, Licad-Coles, Estefania, Kroetz, Deanna L, Szklarz, Grazyna, Harlow, Greg, Halpert, James R, Correia, Maria Almira
Published in Biochemistry (Easton) (08.09.1998)
Published in Biochemistry (Easton) (08.09.1998)
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Journal Article
Biomechanical Considerations in the Orthodontic Treatment of a Patient with Stabilised Stage IV Grade C Generalised Periodontitis: A Case Report
Sum, Fung Hou Kumoi Mineaki Howard, Shan, Zhiyi, Chan, Yat Him Dave, Chu, Ryan Julian Dick Hei, Pelekos, George, She, Tsang Tsang
Published in Bioengineering (Basel) (01.04.2024)
Published in Bioengineering (Basel) (01.04.2024)
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Journal Article