Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase
Walker, John K., Selness, Shaun R., Devraj, Rajesh V., Hepperle, Michael E., Naing, Win, Shieh, Huey, Kurambail, Ravi, Yang, Syaulan, Flynn, Daniel L., Benson, Alan G., Messing, Dean M., Dice, Tom, Kim, Tina, Lindmark, R.J., Monahan, Joseph B., Portanova, Joseph
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
Get full text
Journal Article
Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS)
Carron, Chris P, Trujillo, John I, Olson, Kirk L, Huang, Wei, Hamper, Bruce C, Dice, Tom, Neal, Bradley E, Pelc, Matthew J, Day, Jacqueline E, Rohrer, Douglas C, Kiefer, James R, Moon, Joseph B, Schweitzer, Barbara A, Blake, Tanisha D, Turner, Steve R, Woerndle, Rhonda, Case, Brenda L, Bono, Christine P, Dilworth, Vickie M, Funckes-Shippy, Christie L, Hood, Becky L, Jerome, Gina M, Kornmeier, Christine M, Radabaugh, Melissa R, Williams, Melanie L, Davies, Michael S, Wegner, Craig D, Welsch, Dean J, Abraham, William M, Warren, Chad J, Dowty, Martin E, Hua, Fengmei, Zutshi, Anup, Yang, Jerry Z, Thorarensen, Atli
Published in ACS medicinal chemistry letters (13.05.2010)
Published in ACS medicinal chemistry letters (13.05.2010)
Get full text
Journal Article
Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade
LINDMARK RICHARD, FENTON RICK, NEUMANN WILLIAM L, LONG SCOTT A, CASE BRENDA, RUEPPEL MELVIN L, TRUJILLO JOHN I, DICE TOM, ZENG QINGPING, PARLOW JOHN J, HAYES MICHAEL J, FRANKLIN GARY W, WANG CHINGNG, SOUTH MICHAEL S, WOOD RHONDA, HUANG HORNGIH, KUSTURIN CARRIE, JONES DARIN E, HUANG WEI, REITZ DAVID B, MAHONEY MATTHEW W
Year of Publication 10.10.2006
Get full text
Year of Publication 10.10.2006
Patent
Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade
South, Michael S, Parlow, John J, Jones, Darin E, Case, Brenda, Dice, Tom, Lindmark, Richard, Hayes, Michael J, Rueppel, Melvin L, Fenton, Rick, Franklin, Gary W, Huang, Horng-Chih, Huang, Wei, Kusturin, Carrie, Long, Scott A, Neumann, William L, Reitz, David B, Trujillo, John I, Wang, Ching-Cheng, Wood, Rhonda, Zeng, Qingping, Mahoney, Matthew W
Year of Publication 10.10.2006
Get full text
Year of Publication 10.10.2006
Patent
SUBSTITUIERTE POLYZYKLISCHE ARYL UND HETEROARYLPYRAZINONE ZUR SELEKTIVEN HEMMUNG VON DER BLUTGERINNUNGSKASKADE
FENTON, RICK, WOOD, RHONDA, ZENG, LINDMARK, RICHARD, SOUTH, S, DICE, TOM, HAYES, J, MAHONEY, W, CASE, BRENDA, REITZ, DAVID B, JONES, E, WANG, CHINGNG, FRANKLIN, W, HUANG, WEI, HUANG, HORNGIH, TRUJILLO, I, LONG, A, RUEPPEL, L, NEUMANN, L, PARLOW, J, KUSTURIN, CARRIE
Year of Publication 09.03.2006
Get full text
Year of Publication 09.03.2006
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
TRUJILLO, JOHN I, NEUMANN, WILLIAM L, ZENG, QUINGPING, HAYES, MICHAEL J, FENTON, RICK, WOOD, RHONDA, LINDMARK, RICHARD, DICE, TOM, PARLOW, JOHN J, CASE, BRENDA, REITZ, DAVID B, LONG, SCOTT A, WANG, CHINGNG, FRANKLIN, GARY W, JONES, DARIN E, HUANG, WEI, HUANG, HORNGIH, RUEPPEL, MELVIN L, KUSTURIN, CARRIE, SOUTH, MICHAEL S
Year of Publication 19.10.2005
Get full text
Year of Publication 19.10.2005
Patent
SUBSTITUIERTE POLYZYKLISCHE ARYL UND HETEROARYLPYRAZINONE ZUR SELEKTIVEN HEMMUNG VON DER BLUTGERINNUNGSKASKADE
FENTON, RICK, WOOD, RHONDA, LONG, SCOTT, A, LINDMARK, RICHARD, HAYES, MICHAEL, J, TRUJILLO, JOHN, I, DICE, TOM, MAHONEY, MATTHEW, W, CASE, BRENDA, REITZ, DAVID B, PARLOW, JOHN, J, WANG, CHINGNG, ZENG, QINGPING, SOUTH, MICHAEL, S, HUANG, WEI, HUANG, HORNGIH, NEUMANN, WILLIAM, L, JONES, DARIN, E, FRANKLIN, GARY, W, RUEPPEL, MELVIN, L, KUSTURIN, CARRIE
Year of Publication 15.04.2005
Get full text
Year of Publication 15.04.2005
Patent
SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
FENTON, RICK, WOOD, RHONDA, LONG, SCOTT, A, LINDMARK, RICHARD, HAYES, MICHAEL, J, TRUJILLO, JOHN, I, DICE, TOM, MAHONEY, MATTHEW, W, CASE, BRENDA, REITZ, DAVID B, PARLOW, JOHN, J, WANG, CHINGNG, SOUTH, MICHAEL, S, HUANG, WEI, HUANG, HORNGIH, NEUMANN, WILLIAM, L, JONES, DARIN, E, FRANKLIN, GARY, W, RUEPPEL, MELVIN, L, KUSTURIN, CARRIE
Year of Publication 06.04.2005
Get full text
Year of Publication 06.04.2005
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
TRUJILLO, JOHN I, NEUMANN, WILLIAM L, HAYES, MICHAEL J, FENTON, RICK, WOOD, RHONDA, LINDMARK, RICHARD, DICE, TOM, PARLOW, JOHN J, CASE, BRENDA, LONG, SCOTT A, WANG, CHINGNG, EITZ, DAVID B, ZENG, QINGPING, FRANKLIN, GARY W, HUANG, WEI, JONES, DARIN E, HUANG, HORNGIH, RUEPPEL, MELVINL, KUSTURIN, CARRIE, SOUTH, MICHAEL S
Year of Publication 24.03.2005
Get full text
Year of Publication 24.03.2005
Patent
SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYLPYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
FENTON, RICK, WOOD, RHONDA, LONG, SCOTT, A, LINDMARK, RICHARD, HAYES, MICHAEL, J, TRUJILLO, JOHN, I, DICE, TOM, JONES, DANN, E, MAHONEY, MATTHEW, W, CASE, BRENDA, PARLOW, JOHN, J, WANG, CHINGNG, REITZ, DADID, B, ZENG, QINGPING, SOUTH, MICHAEL, S, HUANG, WEI, HUANG, HORNGIH, NEUMANN, WILLIAM, L, FRANKLIN, GARY, W, RUEPPEL, MELVIN, L, KUSTURIN, CARRIE
Year of Publication 28.10.2004
Get full text
Year of Publication 28.10.2004
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
GARY W. FRANKLIN, JOHN J. PARLOW, MELVIN L. RUEPPEL, HORNGIH HUANG, RHONDA WOOD, CURRIE KUSTURIN, RICK FENTON, CHINGNG WANG, QINGPING ZENG, BRENDA CASE, DAVID B. REITZ, WILLIAM L. NEUMANN, MATTHEWS W. MAHONEY, MICHAEL S. SOUTH, MICHAEL J. HAYES, WEI HUANG, SCOTT A. LONG, TOM DICE, DARIN E. JONES, JOHN I. TRUJILLO, RICHARD LINDMARK
Year of Publication 29.09.2004
Get full text
Year of Publication 29.09.2004
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
GARY W. FRANKLIN, JOHN J. PARLOW, MELVIN L. RUEPPEL, CARRIE KUSTURIN, HORNGIH HUANG, RHONDA WOOD, RICK FENTON, DANN E. JONES, CHINGNG WANG, MATTHEW W. MAHONEY, QINGPING ZENG, BRENDA CASE, DAVID B. REITZ, WILLIAM L NEUMANN, MICHAEL S. SOUTH, MICHAEL J. HAYES, WEI HUANG, SCOTT A. LONG, TOM DICE, JOHN I. TRUJILLO, RICHARD LINDMARK
Year of Publication 22.07.2004
Get full text
Year of Publication 22.07.2004
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
South, Michael, Parlow, John, Jones, Darin, Case, Brenda, Dice, Tom, Lindmark, Richard, Hayes, Michael, Rueppel, Melvin, Huang, Horng-Chih, Huang, Wei, Long, Scott, Mahoney, Matthew, Neumann, William, Reitz, David, Trujillo, John, Wang, Ching-Cheng, Wood, Rhonda, Zeng, Qingping, Fenton, Rick, Franklin, Gary, Kusturin, Carrie
Year of Publication 27.05.2004
Get full text
Year of Publication 27.05.2004
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
LINDMARK RICHARD, NEUMANN WILLIAM L, FENTON RICK, LONG SCOTT A, CASE BRENDA, RUEPPEL MELVIN L, TRUJILLO JOHN I, DICE TOM, ZENG QINGPING, PARLOW JOHN J, HAYES MICHAEL J, WANG CHINGNG, FRANKLIN GARY W, SOUTH MICHAEL S, WOOD RHONDA, HUANG HORNGIH, KUSTURIN CARRIE, JONES DARIN E, HUANG WEI, REITZ DAVID B, MAHONEY MATTHEW W
Year of Publication 27.05.2004
Get full text
Year of Publication 27.05.2004
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
GARY W. FRANKLIN, JOHN J. PARLOW, MELVIN L. RUEPPEL, CARRIE KUSTURIN, HORNGIH HUANG, RHONDA WOOD, RICK FENTON, CHINGNG WANG, MATTHEW W. MAHONEY, QINGPING ZENG, BRENDA CASE, DAVID B. REITZ, WILLIAM L. NEUMANN, MICHAEL S. SOUTH, MICHAEL J. HAYES, WEI HUANG, SCOTT A. LONG, TOM DICE, DARIN E. JONES, JOHN I. TRUJILLO, RICHARD LINDMARK
Year of Publication 26.05.2004
Get full text
Year of Publication 26.05.2004
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
LINDMARK RICHARD, REITZ DAVID, NEUMANN WILLIAM L, FENTON RICK, LONG SCOTT A, CASE BRENDA, RUEPPEL MELVIN L, TRUJILLO JOHN I, SOUTH MICHAEL, DICE TOM, ZENG QINGPING, PARLOW JOHN J, HAYES MICHAEL J, WANG CHINGNG, FRANKLIN GARY W, WOOD RHONDA, HUANG HORNGIH, KUSTURIN CARRIE, JONES DARIN E, HUANG WEI, MAHONEY MATTHEW
Year of Publication 16.12.2003
Get full text
Year of Publication 16.12.2003
Patent
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
South, Michael, Parlow, John J, Jones, Darin E, Case, Brenda, Dice, Tom, Lindmark, Richard, Hayes, Michael J, Rueppel, Melvin L, Huang, Horng-Chih, Huang, Wei, Long, Scott A, Mahoney, Matthew, Neumann, William L, Reitz, David, Trujillo, John I, Wang, Ching-Cheng, Wood, Rhonda, Zeng, Qingping, Fenton, Rick, Franklin, Gary W, Kusturin, Carrie
Year of Publication 16.12.2003
Get full text
Year of Publication 16.12.2003
Patent
SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
LINDMARK RICHARD, FENTON RICK, NEUMANN WILLIAM L, LONG SCOTT A, CASE BRENDA, RUEPPEL MELVIN L, TRUJILLO JOHN I, DICE TOM, PARLOW JOHN J, HAYES MICHAEL J, FRANKLIN GARY W, WANG CHINGNG, SOUTH MICHAEL S, WOOD RHONDA, HUANG HORNGIH, KUSTURIN CARRIE, HUANG WEI, REITZ DAVID B, MAHONEY MATTHEW W, JONES DANN E, ZENG QINGPENG
Year of Publication 25.08.2003
Get full text
Year of Publication 25.08.2003
Patent
SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
FENTON, RICK, WOOD, RHONDA, LONG, SCOTT, A, LINDMARK, RICHARD, HAYES, MICHAEL, J, TRUJILLO, JOHN, I, DICE, TOM, MAHONEY, MATTHEW, W, CASE, BRENDA, PARLOW, JOHN, J, WANG, CHINGNG, SOUTH, MICHAEL, S, HUANG, WEI, HUANG, HORNGIH, NEUMANN, WILLIAM, L, JONES, DARIN, E, FRANKLIN, GARY, W, RUEPPEL, MELVIN, L, KUSTURIN, CARRIE, REITZ, DAVID
Year of Publication 19.03.2003
Get full text
Year of Publication 19.03.2003
Patent