p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway
Duran, Angeles, Amanchy, Ramars, Linares, Juan F., Joshi, Jayashree, Abu-Baker, Shadi, Porollo, Aleksey, Hansen, Malene, Moscat, Jorge, Diaz-Meco, Maria T.
Published in Molecular cell (07.10.2011)
Published in Molecular cell (07.10.2011)
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Journal Article
p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
Duran, Angeles, Hernandez, Eloy D., Reina-Campos, Miguel, Castilla, Elias A., Subramaniam, Shankar, Raghunandan, Sindhu, Roberts, Lewis R., Kisseleva, Tatiana, Karin, Michael, Diaz-Meco, Maria T., Moscat, Jorge
Published in Cancer cell (10.10.2016)
Published in Cancer cell (10.10.2016)
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Journal Article
Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
Valencia, Tania, Kim, Ji Young, Abu-Baker, Shadi, Moscat-Pardos, Jorge, Ahn, Christopher S., Reina-Campos, Miguel, Duran, Angeles, Castilla, Elias A., Metallo, Christian M., Diaz-Meco, Maria T., Moscat, Jorge
Published in Cancer cell (14.07.2014)
Published in Cancer cell (14.07.2014)
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Journal Article
Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration
Ramesh Babu, J, Lamar Seibenhener, M, Peng, Junmin, Strom, Anna-Lena, Kemppainen, Robert, Cox, Nancy, Zhu, Haining, Wooten, Michael C, Diaz-Meco, María T, Moscat, Jorge, Wooten, Marie W
Published in Journal of neurochemistry (01.07.2008)
Published in Journal of neurochemistry (01.07.2008)
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Journal Article
Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCζ in Tumorigenesis
Ma, Li, Tao, Yongzhen, Duran, Angeles, Llado, Victoria, Galvez, Anita, Barger, Jennifer F., Castilla, Elias A., Chen, Jing, Yajima, Tomoko, Porollo, Aleksey, Medvedovic, Mario, Brill, Laurence M., Plas, David R., Riedl, Stefan J., Leitges, Michael, Diaz-Meco, Maria T., Richardson, Adam D., Moscat, Jorge
Published in Cell (31.01.2013)
Published in Cell (31.01.2013)
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Journal Article
Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade
Linares, Juan F., Duran, Angeles, Reina-Campos, Miguel, Aza-Blanc, Pedro, Campos, Alex, Moscat, Jorge, Diaz-Meco, Maria T.
Published in Cell reports (Cambridge) (25.08.2015)
Published in Cell reports (Cambridge) (25.08.2015)
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Journal Article
Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ
Llado, Victoria, Nakanishi, Yuki, Duran, Angeles, Reina-Campos, Miguel, Shelton, Phillip M., Linares, Juan F., Yajima, Tomoko, Campos, Alex, Aza-Blanc, Pedro, Leitges, Michael, Diaz-Meco, Maria T., Moscat, Jorge
Published in Cell reports (Cambridge) (10.02.2015)
Published in Cell reports (Cambridge) (10.02.2015)
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Journal Article
Essential Role of Sequestosome 1/p62 in Regulating Accumulation of Lys63-ubiquitinated Proteins
Wooten, Marie W., Geetha, Thangiah, Babu, J. Ramesh, Seibenhener, M. Lamar, Peng, Junmin, Cox, Nancy, Diaz-Meco, Maria-T., Moscat, Jorge
Published in The Journal of biological chemistry (14.03.2008)
Published in The Journal of biological chemistry (14.03.2008)
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Journal Article
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
Zhong, Zhenyu, Umemura, Atsushi, Sanchez-Lopez, Elsa, Liang, Shuang, Shalapour, Shabnam, Wong, Jerry, He, Feng, Boassa, Daniela, Perkins, Guy, Ali, Syed Raza, McGeough, Matthew D., Ellisman, Mark H., Seki, Ekihiro, Gustafsson, Asa B., Hoffman, Hal M., Diaz-Meco, Maria T., Moscat, Jorge, Karin, Michael
Published in Cell (25.02.2016)
Published in Cell (25.02.2016)
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Journal Article
A Macrophage NBR1-MEKK3 Complex Triggers JNK-Mediated Adipose Tissue Inflammation in Obesity
Hernandez, Eloy D., Lee, Sang Jun, Kim, Ji Young, Duran, Angeles, Linares, Juan F., Yajima, Tomoko, Müller, Timo D., Tschöp, Matthias H., Smith, Steven R., Diaz-Meco, Maria T., Moscat, Jorge
Published in Cell metabolism (02.09.2014)
Published in Cell metabolism (02.09.2014)
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Journal Article
p62 Is Required for Stem Cell/Progenitor Retention through Inhibition of IKK/NF-κB/Ccl4 Signaling at the Bone Marrow Macrophage-Osteoblast Niche
Chang, Kyung Hee, Sengupta, Amitava, Nayak, Ramesh C., Duran, Angeles, Lee, Sang Jun, Pratt, Ronald G., Wellendorf, Ashley M., Hill, Sarah E., Watkins, Marcus, Gonzalez-Nieto, Daniel, Aronow, Bruce J., Starczynowski, Daniel T., Civitelli, Roberto, Diaz-Meco, Maria T., Moscat, Jorge, Cancelas, Jose A.
Published in Cell reports (Cambridge) (24.12.2014)
Published in Cell reports (Cambridge) (24.12.2014)
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Journal Article
A functional role for the p62-ERK1 axis in the control of energy homeostasis and adipogenesis
Lee, Sang Jun, Pfluger, Paul T, Kim, Ji Young, Nogueiras, Ruben, Duran, Angeles, Pagès, Gilles, Pouysségur, Jacques, Tschöp, Matthias H, Diaz-Meco, Maria T, Moscat, Jorge
Published in EMBO reports (01.03.2010)
Published in EMBO reports (01.03.2010)
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Journal Article
p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells
Umemura, Atsushi, He, Feng, Taniguchi, Koji, Nakagawa, Hayato, Yamachika, Shinichiro, Font-Burgada, Joan, Zhong, Zhenyu, Subramaniam, Shankar, Raghunandan, Sindhu, Duran, Angeles, Linares, Juan F., Reina-Campos, Miguel, Umemura, Shiori, Valasek, Mark A., Seki, Ekihiro, Yamaguchi, Kanji, Koike, Kazuhiko, Itoh, Yoshito, Diaz-Meco, Maria T., Moscat, Jorge, Karin, Michael
Published in Cancer cell (13.06.2016)
Published in Cancer cell (13.06.2016)
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Journal Article
NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly
He, Feng, Antonucci, Laura, Yamachika, Shinichiro, Zhang, Zechuan, Taniguchi, Koji, Umemura, Atsushi, Hatzivassiliou, Georgia, Roose-Girma, Merone, Reina-Campos, Miguel, Duran, Angeles, Diaz-Meco, Maria T., Moscat, Jorge, Sun, Beicheng, Karin, Michael
Published in Journal of hepatology (01.06.2020)
Published in Journal of hepatology (01.06.2020)
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