Search Results - "Diago, Oscar" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma

by Cloughesy, Timothy F, Landolfi, Joseph, Hogan, Daniel J, Bloomfield, Stephen, Carter, Bob, Chen, Clark C, Elder, J Bradley, Kalkanis, Steven N, Kesari, Santosh, Lai, Albert, Lee, Ian Y, Liau, Linda M, Mikkelsen, Tom, Nghiemphu, Phioanh Leia, Piccioni, David, Walbert, Tobias, Chu, Alice, Das, Asha, Diago, Oscar R, Gammon, Dawn, Gruber, Harry E, Hanna, Michelle, Jolly, Douglas J, Kasahara, Noriyuki, McCarthy, David, Mitchell, Leah, Ostertag, Derek, Robbins, Joan M, Rodriguez-Aguirre, Maria, Vogelbaum, Michael A
Published in Science translational medicine (01.06.2016)

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Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC

Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC

by Cloughesy, Timothy F, Landolfi, Joseph, Vogelbaum, Michael A, Ostertag, Derek, Elder, James B, Bloomfield, Stephen, Carter, Bob, Chen, Clark C, Kalkanis, Steven N, Kesari, Santosh, Lai, Albert, Lee, Ian Y, Liau, Linda M, Mikkelsen, Tom, Nghiemphu, Phioanh, Piccioni, David, Accomando, William, Diago, Oscar R, Hogan, Daniel J, Gammon, Dawn, Kasahara, Noriyuki, Kheoh, Thian, Jolly, Douglas J, Gruber, Harry E, Das, Asha, Walbert, Tobias
Published in Neuro-oncology (Charlottesville, Va.) (03.09.2018)

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Molecular Analyses Support the Safety and Activity of Retroviral Replicating Vector Toca 511 in Patients

Molecular Analyses Support the Safety and Activity of Retroviral Replicating Vector Toca 511 in Patients

by Hogan, Daniel J, Zhu, Jay-Jiguang, Diago, Oscar R, Gammon, Dawn, Haghighi, Ali, Lu, Guangrong, Das, Asha, Gruber, Harry E, Jolly, Douglas J, Ostertag, Derek
Published in Clinical cancer research (01.10.2018)

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Molecular and Immunologic Signatures are Related to Clinical Benefit from Treatment with Vocimagene Amiretrorepvec (Toca 511) and 5-Fluorocytosine (Toca FC) in Patients with Glioma

Molecular and Immunologic Signatures are Related to Clinical Benefit from Treatment with Vocimagene Amiretrorepvec (Toca 511) and 5-Fluorocytosine (Toca FC) in Patients with Glioma

by Accomando, William P, Rao, Aliz R, Hogan, Daniel J, Newman, Aaron M, Nakao, Aki, Alizadeh, Ash A, Diehn, Maximilian, Diago, Oscar R, Gammon, Dawn, Haghighi, Ali, Gruber, Harry E, Jolly, Douglas J, Ostertag, Derek
Published in Clinical cancer research (01.12.2020)

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Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model

Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model

by Huang, Tiffany T, Parab, Shraddha, Burnett, Ryan, Diago, Oscar, Ostertag, Derek, Hofman, Florence M, Espinoza, Fernando Lopez, Martin, Bryan, Ibañez, Carlos E, Kasahara, Noriyuki, Gruber, Harry E, Pertschuk, Daniel, Jolly, Douglas J, Robbins, Joan M
Published in Human gene therapy (01.02.2015)

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Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-Fluorouracil-Mediated Cytotoxicity in Multiple Human Cancer Types

Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-Fluorouracil-Mediated Cytotoxicity in Multiple Human Cancer Types

by Twitty, Chris G, Diago, Oscar R, Hogan, Daniel J, Burrascano, Cindy, Ibanez, Carlos E, Jolly, Douglas J, Ostertag, Derek
Published in Human gene therapy. Part B. Methods (01.02.2016)

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MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples

MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples

by McCarthy, David, Pulverer, Walter, Weinhaeusel, Andreas, Diago, Oscar R, Hogan, Daniel J, Ostertag, Derek, Hanna, Michelle M
Published in Epigenomics (01.06.2016)

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MicroRNA 142-3p attenuates spread of replicating retroviral vector in hematopoietic lineage-derived cells while maintaining an antiviral immune response

MicroRNA 142-3p attenuates spread of replicating retroviral vector in hematopoietic lineage-derived cells while maintaining an antiviral immune response

by Lin, Amy H, Timberlake, Nina, Logg, Christopher R, Liu, Yanzheng, Kamijima, Shuichi, Diago, Oscar, Wong, Kenneth, Gammon, Dawn K, Ostertag, Derek, Hacke, Katrin, Yang, Emily C, Gruber, Harry, Kasahara, Noriyuki, Jolly, Douglas J
Published in Human gene therapy (01.08.2014)

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ATIM-24. SYSTEMATIC IDENTIFICATION OF TOCA 511 RETROVIRUS INTEGRATION SITES AND MUTATION PROFILES IN TUMOR AND BLOOD SAMPLES FROM PATIENTS UNDERGOING INVESTIGATIONAL TREATMENT FOR RECURRENT HIGH GRADE GLIOMA CORRELATES WITH FAVORABLE CLINICAL SAFETY PROFILE

by Hogan, Daniel, Diago, Oscar
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)

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GENT-42. SIMULTANEOUS MEASUREMENT OF MGMT METHYLATION AND DETERMINATION OF IDH1 R132H AND CpG ISLAND METHYLATOR PHENOTYPE (CIMP) IN GLIOMAS USING COUPLED ABSCRIPTION PCR SIGNALING (CAPS)

GENT-42. SIMULTANEOUS MEASUREMENT OF MGMT METHYLATION AND DETERMINATION OF IDH1 R132H AND CpG ISLAND METHYLATOR PHENOTYPE (CIMP) IN GLIOMAS USING COUPLED ABSCRIPTION PCR SIGNALING (CAPS)

by McCarthy, David, Diago, Oscar, Hogan, Daniel, Ostertag, Derek, Hanna, Michelle
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)

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Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

by Perez, Omar D, Logg, Christopher R, Hiraoka, Kei, Diago, Oscar, Burnett, Ryan, Inagaki, Akihito, Jolson, Dawn, Amundson, Karin, Buckley, Taylor, Lohse, Dan, Lin, Amy, Burrascano, Cindy, Ibanez, Carlos, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J
Published in Molecular therapy (01.09.2012)

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Abstract 5630: Immune profile of tumor microenvironment helps predict response in patients treated with an investigational immunotherapeutic consisting of a retroviral replicating vector (Toca 511) and an extended-release formulation of 5-fluorocytosine (Toca FC)

by Ostertag, Derek, Accomando, William, Mitchell, Leah, Rodriguez-Aguirre, Maria, Hogan, Daniel, Diago, Oscar, Gammon, Dawn, Haghighi, Ali, Gruber, Harry, Das, Asha, Jolly, Douglas
Published in Cancer research (Chicago, Ill.) (01.07.2018)

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Abstract B010: Antitumor cellular immune response elicited by Toca 511 and Toca FC therapy in preclinical and clinical studies

Abstract B010: Antitumor cellular immune response elicited by Toca 511 and Toca FC therapy in preclinical and clinical studies

by Montellano, Tiffany T., Ostertag, Derek, Hogan, Daniel J., Diago, Oscar R., Gammon, Dawn, Haghighi, Ali, Accomando, William, Mitchell, Leah, Das, Asha, Gruber, Harry, Jolly, Douglas J.
Published in Molecular cancer therapeutics (01.01.2018)

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ATIM-26. IMMUNOLOGIC TRENDS ASSOCIATED WITH PATIENT OUTCOMES IN A PHASE 1 CLINICAL TRIAL OF TOCA 511 AND TOCA FC IN RECURRENT HIGH GRADE GLIOMA

ATIM-26. IMMUNOLOGIC TRENDS ASSOCIATED WITH PATIENT OUTCOMES IN A PHASE 1 CLINICAL TRIAL OF TOCA 511 AND TOCA FC IN RECURRENT HIGH GRADE GLIOMA

by Accomando, William, Cloughesy, Timothy, Kalkanis, Steven, Mikkelsen, Tom, Landolfi, Joseph, Carter, Bob, Chen, Clark, Vogelbaum, Michael, Elder, James, Piccioni, David, Walbert, Tobias, Hogan, Daniel, Diago, Oscar, Gammon, Dawn, Haghighi, Ali, Kheoh, Thian, Gruber, Harry, Jolly, Douglas, Ostertag, Derek
Published in Neuro-oncology (Charlottesville, Va.) (05.11.2018)

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227. Cancer Cell Susceptibility To Treatment With a Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Is Likely To Be Common

227. Cancer Cell Susceptibility To Treatment With a Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Is Likely To Be Common

by Twitty, Chris G., Diago, Oscar R., Hogan, Daniel, Burrascano, Cindy, Ibanez, Carlos E., Jolly, Douglas J., Ostertag, Derek
Published in Molecular therapy (01.05.2015)

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ATIM-25. IMMUNOLOGICAL ACTIVATION IN RESPONDING PATIENTS WITH RECURRENT HGG AFTER TREATMENT WITH TOCA 511 & TOCA FC: RESULTS FROM A PHASE 1 TRIAL

ATIM-25. IMMUNOLOGICAL ACTIVATION IN RESPONDING PATIENTS WITH RECURRENT HGG AFTER TREATMENT WITH TOCA 511 & TOCA FC: RESULTS FROM A PHASE 1 TRIAL

by Ostertag, Derek, Accomando, William, Hogan, Daniel, Diago, Oscar, Gammon, Dawn, Haghighi, Ali, Mitchell, Leah, Rodriguez-Aquirre, Maria, Cloughesy, Timothy, Kalkanis, Steven, Mikkelsen, Tom, Landolfi, Joseph, Chen, Clark, Vogelbaum, Michael, Gruber, Harry, Das, Asha, Jolly, Douglas
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)

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Abstract A085: Durable responses observed in recurrent high-grade glioma (rHGG) with Toca 511 and Toca FC treatment

Abstract A085: Durable responses observed in recurrent high-grade glioma (rHGG) with Toca 511 and Toca FC treatment

by Cloughesy, Timothy F., Landolfi, Joseph, Vogelbaum, Michael, Ostertag, Derek, Elder, Bradley, Carter, Bob, Chen, Clark C., Kalkanis, Steven, Kesari, Santosh, Lai, Albert, Lee, Ian, Liau, Linda, Mikkelsen, Tom, Nghiemphu, Leia, Piccioni, David, Accomando, William, Diago, Oscar, Hogan, Daniel, Jolly, Douglas J., Wood, Katie, Gruber, Harry, Das, Asha, Walbert, Tobias
Published in Molecular cancer therapeutics (01.01.2018)

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Improved Retroviral Replicating Vectors for Prodrug-Activator Gene Therapy of Cancer

Improved Retroviral Replicating Vectors for Prodrug-Activator Gene Therapy of Cancer

by Kasahara, Noriyuki, Logg, Christopher, Perez, Omar, Diago, Oscar, Burnett, Ryan, Inagaki, Aki, Lin, Amy, Burrascano, Cindy, Berger, Mitchel, Bankiewicz, Krystof
Published in Molecular therapy (01.09.2013)

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ATIM-02. DURABLE RESPONSES OBSERVED IN IDH1 WILDTYPE AND MUTANT RECURRENT HIGH GRADE GLIOMA (rHGG) WITH TOCA 511 & TOCA FC TREATMENT

ATIM-02. DURABLE RESPONSES OBSERVED IN IDH1 WILDTYPE AND MUTANT RECURRENT HIGH GRADE GLIOMA (rHGG) WITH TOCA 511 & TOCA FC TREATMENT

by Cloughesy, Timothy, Landolfi, Joseph, Vogelbaum, Michael, Ostertag, Derek, Elder, Bradley, Carter, Bob, Chen, Clark, Kalkanis, Steven, Lai, Albert, Mikkelsen, Tom, Nghiemphu, Phioanh, Piccioni, David, Accomando, William, Diago, Oscar, Hogan, Daniel, Jolly, Douglas, Wood, Katie, Yang, Liqiang, Gruber, Harry, Das, Asha, Walbert, Tobias
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)

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MethylMeter

MethylMeter

by McCarthy, David, Pulverer, Walter, Weinhaeusel, Andreas, Diago, Oscar R, Hogan, Daniel J, Ostertag, Derek, Hanna, Michelle M
Published in Epigenomics (01.06.2016)

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